2A9J
 
 | |
3HO1
 | | Crystal structure of T. thermophilus Argonaute N546 mutant protein complexed with DNA guide strand and 12-nt RNA target strand | | 分子名称: | 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*T*AP*GP*T)-3', 5'-R(P*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', MAGNESIUM ION, ... | | 著者 | Wang, Y, Li, H, Sheng, G, Patel, D.J. | | 登録日 | 2009-06-01 | | 公開日 | 2009-10-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
|
|
143D
 | |
3HVR
 | | Crystal structure of T. thermophilus Argonaute complexed with DNA guide strand and 19-nt RNA target strand with two Mg2+ at the cleavage site | | 分子名称: | 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*TP*GP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', Argonaute, ... | | 著者 | Wang, Y, Li, H, Sheng, G, Patel, D.J. | | 登録日 | 2009-06-16 | | 公開日 | 2009-10-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.211 Å) | | 主引用文献 | Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
|
|
3HM9
 | | Crystal structure of T. thermophilus Argonaute complexed with DNA guide strand and 19-nt RNA target strand | | 分子名称: | 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', Argonaute, ... | | 著者 | Wang, Y, Li, H, Sheng, G, Patel, D.J. | | 登録日 | 2009-05-28 | | 公開日 | 2009-10-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
|
|
3HXM
 | | Structure of an argonaute complexed with guide DNA and target RNA duplex containing two mismatches. | | 分子名称: | Argonaute, DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), MAGNESIUM ION, ... | | 著者 | Wang, Y, Li, H, Sheng, G, Patel, D.J. | | 登録日 | 2009-06-21 | | 公開日 | 2009-10-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
|
|
6LX3
 | | Cryo-EM structure of human secretory immunoglobulin A | | 分子名称: | Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor | | 著者 | Wang, Y, Wang, G, Li, Y, Xiao, J. | | 登録日 | 2020-02-10 | | 公開日 | 2020-05-27 | | 最終更新日 | 2020-07-22 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
|
|
5EX7
 | | Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA | | 分子名称: | Brain tumor protein, RNA (5'-R(P*UP*UP*UP*GP*UP*UP*GP*U)-3') | | 著者 | Wang, Y, Yu, Z, Wang, M, Liu, C.P, Yang, N, Xu, R.M. | | 登録日 | 2015-11-23 | | 公開日 | 2015-12-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA
To Be Published
|
|
4X3O
 | | Sirt2 in complex with a myristoyl peptide | | 分子名称: | 1,2-ETHANEDIOL, NAD-dependent protein deacetylase sirtuin-2, ZINC ION, ... | | 著者 | Wang, Y, Zhang, W.Z, Hao, Q. | | 登録日 | 2014-12-01 | | 公開日 | 2016-01-13 | | 最終更新日 | 2022-04-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure.
Cell Chem Biol, 24, 2017
|
|
4X3P
 | | Sirt2 in complex with a myristoyl peptide | | 分子名称: | 1,2-ETHANEDIOL, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NAD-dependent protein deacetylase sirtuin-2, ... | | 著者 | Wang, Y, Zhang, W, Hao, Q. | | 登録日 | 2014-12-01 | | 公開日 | 2016-01-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure.
Cell Chem Biol, 24, 2017
|
|
4XCH
 | |
3K64
 | | Crystal structure of FBF-2/fem-3 PME complex | | 分子名称: | 5'-R(*UP*GP*UP*GP*UP*CP*AP*UP*U)-3', Fem-3 mRNA-binding factor 2 | | 著者 | Wang, Y, Opperman, L, Wickens, M, Hall, T.M.T. | | 登録日 | 2009-10-08 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3K61
 | | Crystal structure of FBF-2/fog-1 FBEa complex | | 分子名称: | 5'-R(*UP*GP*UP*AP*AP*AP*AP*UP*C)-3', Fem-3 mRNA-binding factor 2 | | 著者 | Wang, Y, Opperman, L, Wickens, M, Hall, T.M.T. | | 登録日 | 2009-10-08 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
179D
 | |
186D
 | |
3K62
 | | Crystal structure of FBF-2/gld-1 FBEb complex | | 分子名称: | 5'-R(*UP*GP*UP*GP*UP*UP*AP*UP*C)-3', Fem-3 mRNA-binding factor 2 | | 著者 | Wang, Y, Opperman, L, Wickens, M, Hall, T.M.T. | | 登録日 | 2009-10-08 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
5CA1
 | | Crystal structure of T2R-TTL-Nocodazole complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | | 著者 | Wang, Y, Yu, Y, Chen, Q, Yang, J. | | 登録日 | 2015-06-29 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
|
|
6LXW
 | | Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA | | 分子名称: | Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor, ... | | 著者 | Wang, Y, Wang, G, Li, Y, Xiao, J. | | 登録日 | 2020-02-12 | | 公開日 | 2020-05-27 | | 最終更新日 | 2020-07-22 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
|
|
5C8Y
 | | Crystal structure of T2R-TTL-Plinabulin complex | | 分子名称: | (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y, Yu, Y, Chen, Q, Yang, J. | | 登録日 | 2015-06-26 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.594 Å) | | 主引用文献 | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
|
|
5CA0
 | | Crystal structure of T2R-TTL-Lexibulin complex | | 分子名称: | 1-ethyl-3-[2-methoxy-4-(5-methyl-4-{[(1S)-1-(pyridin-3-yl)butyl]amino}pyrimidin-2-yl)phenyl]urea, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y, Yu, Y, Chen, Q, Yang, J. | | 登録日 | 2015-06-29 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
|
|
3K5Q
 | | Crystal structure of FBF-2/FBE complex | | 分子名称: | 5'-R(P*UP*GP*UP*AP*CP*UP*AP*UP*A)-3', Fem-3 mRNA-binding factor 2 | | 著者 | Wang, Y, Opperman, L, Wickens, M, Hall, T.M.T. | | 登録日 | 2009-10-07 | | 公開日 | 2009-11-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3K5Z
 | | Crystal structure of FBF-2/gld-1 FBEa G4A mutant complex | | 分子名称: | 5'-R(*UP*GP*UP*AP*CP*CP*AP*UP*A)-3', Fem-3 mRNA-binding factor 2 | | 著者 | Wang, Y, Opperman, L, Wickens, M, Hall, T.M.T. | | 登録日 | 2009-10-08 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3K5Y
 | | Crystal structure of FBF-2/gld-1 FBEa complex | | 分子名称: | 5'-R(*UP*GP*UP*GP*CP*CP*AP*UP*A)-3', Fem-3 mRNA-binding factor 2 | | 著者 | Wang, Y, Opperman, L, Wickens, M, Hall, T.M.T. | | 登録日 | 2009-10-08 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
5CB4
 | | Crystal structure of T2R-TTL-Tivantinib complex | | 分子名称: | (3R,4R)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y, Yu, Y, Chen, Q, Yang, J. | | 登録日 | 2015-06-30 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.193 Å) | | 主引用文献 | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
|
|
2F90
 | | Crystal structure of bisphosphoglycerate mutase in complex with 3-phosphoglycerate and AlF4- | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, TETRAFLUOROALUMINATE ION | | 著者 | Wang, Y, Liu, L, Wei, Z, Gong, W. | | 登録日 | 2005-12-05 | | 公開日 | 2006-10-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase
J.Biol.Chem., 281, 2006
|
|
