6U9U
 
 | | Structure of GM9_TH8seq732127 FAB | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, GM9_TH8seq732127 FAB heavy chain, ... | | 著者 | Singh, S, Liban, T.J, Pancera, M. | | 登録日 | 2019-09-09 | | 公開日 | 2019-11-06 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
J.Exp.Med., 217, 2020
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6U3Z
 | | Structure of VD20_5A4 Fab | | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Dionne, G, Shapiro, L. | | 登録日 | 2019-08-22 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.99002314 Å) | | 主引用文献 | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
J.Exp.Med., 217, 2020
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8G8A
 | | Crystal structure of DH1317.8 Fab in complex with HIV proximal MPER peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1317.8 heavy chain, DH1317.8 light chain, ... | | 著者 | Janus, B.M, Astavans, A, Ofek, G. | | 登録日 | 2023-02-17 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
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8G8C
 | | Crystal structure of DH1322.1 Fab in complex with HIV proximal MPER peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1322.1 heavy chain, DH1322.1 light chain, ... | | 著者 | Niyongabo, A, Janus, B.M, Ofek, G. | | 登録日 | 2023-02-17 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
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8G8D
 | | Crystal structure of DH1346 Fab in complex with HIV proximal MPER peptide | | 分子名称: | DH1346 heavy chain, DH1346 light chain, FLUORIDE ION, ... | | 著者 | Niyongabo, A, Janus, B.M, Ofek, G. | | 登録日 | 2023-02-17 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
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1QPF
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1QPL
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5V3R
 | | CHMP4C in complex with ALIX BRO1 | | 分子名称: | Charged multivesicular body protein 4c, Programmed cell death 6-interacting protein | | 著者 | Wenzel, D.M, Alam, S.L, Sundquist, W.I. | | 登録日 | 2017-03-08 | | 公開日 | 2018-09-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.906 Å) | | 主引用文献 | A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5WA1
 | | CHMP4C A232T in complex with ALIX BRO1 | | 分子名称: | Charged multivesicular body protein 4c, Programmed cell death 6-interacting protein | | 著者 | Wenzel, D.M, Alam, S.L, Sundquist, W.I. | | 登録日 | 2017-06-24 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.868 Å) | | 主引用文献 | A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7UB0
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7UB6
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7UB5
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8CP6
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8DKF
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5USJ
 | | Crystal Structure of human KRAS G12D mutant in complex with GDPNP | | 分子名称: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Huang, C.S, Kaplan, A, Stockwell, B.R, Tong, L. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Multivalent Small-Molecule Pan-RAS Inhibitors.
Cell, 168, 2017
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5US4
 | | Crystal structure of human KRAS G12D mutant in complex with GDP | | 分子名称: | GLYCEROL, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Tran, T, Kaplan, A, Stockwell, B.R, Tong, L. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Multivalent Small-Molecule Pan-RAS Inhibitors.
Cell, 168, 2017
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5UQW
 | | Crystal structure of human KRAS G12V mutant in complex with GDP | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Huang, C.S, Kaplan, A, Stockwell, B.R, Tong, L. | | 登録日 | 2017-02-08 | | 公開日 | 2017-03-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Multivalent Small-Molecule Pan-RAS Inhibitors.
Cell, 168, 2017
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7KDE
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8BXJ
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8C2Q
 | | Silver ion-bound structure of the silver specific chaperone SilF needed for bacterial silver resistance | | 分子名称: | Copper ABC transporter substrate-binding protein, SILVER ION | | 著者 | Monneau, Y.R, Walker, O, Hologne, M. | | 登録日 | 2022-12-22 | | 公開日 | 2023-10-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The battle for silver binding: How the interplay between the SilE, SilF, and SilB proteins contributes to the silver efflux pump mechanism.
J.Biol.Chem., 299, 2023
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6Z45
 | | CDK9-Cyclin-T1 complex bound by compound 24 | | 分子名称: | (1~{S},3~{R})-3-acetamido-~{N}-[5-chloranyl-4-(5,5-dimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl]cyclohexane-1-carboxamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cyclin-T1, ... | | 著者 | Ferguson, A, Collie, G.W. | | 登録日 | 2020-05-22 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | | 主引用文献 | Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies.
J.Med.Chem., 63, 2020
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1I3Z
 | | MURINE EAT2 SH2 DOMAIN IN COMPLEX WITH SLAM PHOSPHOPEPTIDE | | 分子名称: | EWS/FLI1 ACTIVATED TRANSCRIPT 2, SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE | | 著者 | Lu, J, Poy, F, Morra, M, Terhorst, C, Eck, M.J. | | 登録日 | 2001-02-19 | | 公開日 | 2003-04-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for the interaction of the free SH2 domain EAT-2 with
SLAM receptors in hematopoietic cells.
Eur.J.Biochem., 20, 2001
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7TEI
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7TF8
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3PY1
 | | CDK2 ternary complex with SU9516 and ANS | | 分子名称: | (3Z)-3-(1H-IMIDAZOL-5-YLMETHYLENE)-5-METHOXY-1H-INDOL-2(3H)-ONE, 1,2-ETHANEDIOL, 8-ANILINO-1-NAPHTHALENE SULFONATE, ... | | 著者 | Betzi, S, Alam, R, Schonbrunn, E. | | 登録日 | 2010-12-10 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Discovery of a Potential Allosteric Ligand Binding Site in CDK2.
Acs Chem.Biol., 6, 2011
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