5V3R

CHMP4C in complex with ALIX BRO1

Summary for 5V3R

• Entry DOI: 10.2210/pdb5v3r/pdb
• Related: 3C3R 5V3K
• Descriptor: Programmed cell death 6-interacting protein, Charged multivesicular body protein 4c (3 entities in total)
• Functional Keywords: cell division, transport protein, abscission checkpoint
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 44753.83

Authors

Wenzel, D.M.,Alam, S.L.,Sundquist, W.I. (deposition date: 2017-03-08, release date: 2018-09-12, Last modification date: 2023-10-04)

• Primary citation: Sadler, J.B.A.,Wenzel, D.M.,Williams, L.K.,Guindo-Martinez, M.,Alam, S.L.,Mercader, J.M.,Torrents, D.,Ullman, K.S.,Sundquist, W.I.,Martin-Serrano, J.; A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.; Proc. Natl. Acad. Sci. U.S.A., 115:E8900-E8908, 2018; PubMed: 30181294; DOI: 10.1073/pnas.1805504115

Experimental method

X-RAY DIFFRACTION (1.906 Å)