4WTS
 
 | | Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaritriose | | 分子名称: | beta-1,3-glucanosyltransferase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose | | 著者 | Qin, Z, Yan, Q, Lei, J, Yang, S, Jiang, Z. | | 登録日 | 2014-10-30 | | 公開日 | 2015-08-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The first crystal structure of a glycoside hydrolase family 17 beta-1,3-glucanosyltransferase displays a unique catalytic cleft.
Acta Crystallogr.,Sect.D, 71, 2015
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3O5Z
 | | Crystal structure of the SH3 domain from p85beta subunit of phosphoinositide 3-kinase (PI3K) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphatidylinositol 3-kinase regulatory subunit beta | | 著者 | Chen, S, Xiao, Y, Ponnusamy, R, Tan, J, Lei, J, Hilgenfeld, R. | | 登録日 | 2010-07-28 | | 公開日 | 2011-08-10 | | 最終更新日 | 2014-09-10 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | X-ray structure of the SH3 domain of the phosphoinositide 3-kinase p85 beta subunit
Acta Crystallogr.,Sect.F, 67, 2011
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5ADY
 | | Cryo-EM structures of the 50S ribosome subunit bound with HflX | | 分子名称: | 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ... | | 著者 | Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N. | | 登録日 | 2015-08-25 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
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5YLF
 | | MCR-1 complex with D-glucose | | 分子名称: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION, beta-D-glucopyranose | | 著者 | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | | 登録日 | 2017-10-17 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
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3J3T
 | | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | | 登録日 | 2013-04-18 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
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3J3R
 | | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | | 登録日 | 2013-04-18 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
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5YLC
 | | Crystal Structure of MCR-1 Catalytic Domain | | 分子名称: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | | 著者 | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | | 登録日 | 2017-10-17 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
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3J3U
 | | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | | 登録日 | 2013-04-18 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
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5YLE
 | | MCR-1 complex with ethanolamine (ETA) | | 分子名称: | ETHANOLAMINE, Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | | 著者 | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | | 登録日 | 2017-10-17 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
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3J3S
 | | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | | 登録日 | 2013-04-18 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (11 Å) | | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
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3J8G
 | | Electron cryo-microscopy structure of EngA bound with the 50S ribosomal subunit | | 分子名称: | 23S rRNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | | 著者 | Zhang, X, Yan, K, Zhang, Y, Li, N, Ma, C, Li, Z, Zhang, Y, Feng, B, Liu, J, Sun, Y, Xu, Y, Lei, J, Gao, N. | | 登録日 | 2014-10-24 | | 公開日 | 2014-11-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
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6M49
 | | cryo-EM structure of Scap/Insig complex in the present of 25-hydroxyl cholesterol. | | 分子名称: | 25-HYDROXYCHOLESTEROL, Insulin-induced gene 2 protein, Sterol regulatory element-binding protein cleavage-activating protein,Sterol regulatory element-binding protein cleavage-activating protein | | 著者 | Yan, R, Cao, P, Song, W, Qian, H, Du, X, Coates, H.W, Zhao, X, Li, Y, Gao, S, Gong, X, Liu, X, Sui, J, Lei, J, Yang, H, Brown, A.J, Zhou, Q, Yan, C, Yan, N. | | 登録日 | 2020-03-06 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols.
Science, 371, 2021
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8HHT
 | | Crystal structure of the SARS-CoV-2 main protease in complex with Hit-1 | | 分子名称: | 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]benzamide | | 著者 | Zeng, R, Xie, L.W, Huang, C, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. | | 登録日 | 2022-11-17 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A new generation M pro inhibitor with potent activity against SARS-CoV-2 Omicron variants.
Signal Transduct Target Ther, 8, 2023
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8HHU
 | | Crystal structure of the SARS-CoV-2 main protease in complex with SY110 | | 分子名称: | (1~{R})-3,3-bis(fluoranyl)-~{N}-[(2~{R})-3-methoxy-1-oxidanylidene-1-[[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]amino]propan-2-yl]cyclohexane-1-carboxamide, 3C-like proteinase nsp5 | | 著者 | Zeng, R, Xie, L.W, Huang, C, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. | | 登録日 | 2022-11-17 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.258 Å) | | 主引用文献 | A new generation M pro inhibitor with potent activity against SARS-CoV-2 Omicron variants.
Signal Transduct Target Ther, 8, 2023
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5XJC
 | | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | | 登録日 | 2017-04-30 | | 公開日 | 2017-07-05 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
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3J2G
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (16.5 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process.
Nucleic Acids Res., 41, 2013
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3J2E
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (15.3 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
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3J2D
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (18.700001 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
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3J28
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (12.9 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
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3J29
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (14 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
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3J2F
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (17.6 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process.
Nucleic Acids Res., 41, 2013
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3J2C
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA body domain, 16S rRNA head domain | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (13.2 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
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3J2H
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (18.799999 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process.
Nucleic Acids Res., 41, 2013
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3J3W
 | | Atomic model of the immature 50S subunit from Bacillus subtilis (state II-a) | | 分子名称: | 50S ribosomal protein L1, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | 著者 | Li, N, Guo, Q, Zhang, Y, Yuan, Y, Ma, C, Lei, J, Gao, N. | | 登録日 | 2013-04-28 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (10.7 Å) | | 主引用文献 | Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
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3J2B
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | 分子名称: | 16S rRNA | | 著者 | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (13.6 Å) | | 主引用文献 | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
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