7WW5
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![BU of 7ww5 by Molmil](/molmil-images/mine/7ww5) | Crystal structure of MutT-8-oxo-dGTP complex | 分子名称: | 7,8-dihydro-8-oxoguanine-triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION, ... | 著者 | Nakamura, T, Yamagata, Y. | 登録日 | 2022-02-12 | 公開日 | 2022-06-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Visualization of mutagenic nucleotide processing by Escherichia coli MutT, a Nudix hydrolase. Proc.Natl.Acad.Sci.USA, 119, 2022
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7X9N
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![BU of 7x9n by Molmil](/molmil-images/mine/7x9n) | Crystal structure of MutT-8-oxo-dGTP complex with three Mg2+ ions: Reaction using Mg2+ | 分子名称: | 7,8-dihydro-8-oxoguanine-triphosphatase, 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Nakamura, T, Yamagata, Y. | 登録日 | 2022-03-15 | 公開日 | 2022-06-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Visualization of mutagenic nucleotide processing by Escherichia coli MutT, a Nudix hydrolase. Proc.Natl.Acad.Sci.USA, 119, 2022
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3A6V
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3A6T
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![BU of 3a6t by Molmil](/molmil-images/mine/3a6t) | Crystal structure of MutT-8-OXO-DGMP complex | 分子名称: | 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, Mutator mutT protein, SODIUM ION, ... | 著者 | Nakamura, T, Yamagata, Y. | 登録日 | 2009-09-09 | 公開日 | 2009-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base J.Biol.Chem., 285, 2010
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3A6U
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![BU of 3a6u by Molmil](/molmil-images/mine/3a6u) | Crystal structure of MutT-8-OXO-dGMP-MN(II) complex | 分子名称: | 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Mutator mutT protein, ... | 著者 | Nakamura, T, Yamagata, Y. | 登録日 | 2009-09-09 | 公開日 | 2009-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base J.Biol.Chem., 285, 2010
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3A6S
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![BU of 3a6s by Molmil](/molmil-images/mine/3a6s) | Crystal structure of the MutT protein | 分子名称: | L(+)-TARTARIC ACID, Mutator mutT protein, SODIUM ION | 著者 | Nakamura, T, Yamagata, Y. | 登録日 | 2009-09-09 | 公開日 | 2009-10-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base J.Biol.Chem., 285, 2010
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3A2W
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![BU of 3a2w by Molmil](/molmil-images/mine/3a2w) | Peroxiredoxin (C50S) from Aeropytum pernix K1 (peroxide-bound form) | 分子名称: | GLYCEROL, PEROXIDE ION, Probable peroxiredoxin | 著者 | Nakamura, T, Kado, Y, Yamaguchi, F, Matsumura, H, Ishikawa, K, Inoue, T. | 登録日 | 2009-06-04 | 公開日 | 2009-10-27 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide J.Biochem., 147, 2010
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3A2V
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![BU of 3a2v by Molmil](/molmil-images/mine/3a2v) | Peroxiredoxin (C207S) from Aeropyrum pernix K1 complexed with hydrogen peroxide | 分子名称: | PEROXIDE ION, Probable peroxiredoxin | 著者 | Nakamura, T, Kado, Y, Yamaguchi, F, Ishikawa, K, Matsumura, H, Inoue, T. | 登録日 | 2009-06-04 | 公開日 | 2009-10-27 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide J.Biochem., 147, 2010
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3A5W
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![BU of 3a5w by Molmil](/molmil-images/mine/3a5w) | Peroxiredoxin (wild type) from Aeropyrum pernix K1 (reduced form) | 分子名称: | Probable peroxiredoxin | 著者 | Nakamura, T, Kado, Y, Yamaguchi, T, Matsumura, H, Ishikawa, K, Inoue, T. | 登録日 | 2009-08-12 | 公開日 | 2009-10-27 | 最終更新日 | 2014-01-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide J.Biochem., 147, 2010
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3A2X
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![BU of 3a2x by Molmil](/molmil-images/mine/3a2x) | Peroxiredoxin (C50S) from Aeropyrum pernix K1 (acetate-bound form) | 分子名称: | ACETATE ION, Probable peroxiredoxin | 著者 | Nakamura, T, Kado, Y, Yamaguchi, F, Matsumura, H, Ishikawa, K, Inoue, T. | 登録日 | 2009-06-04 | 公開日 | 2009-10-27 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide J.Biochem., 147, 2010
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3VOV
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![BU of 3vov by Molmil](/molmil-images/mine/3vov) | Crystal Structure of ROK Hexokinase from Thermus thermophilus | 分子名称: | GLYCEROL, Glucokinase, ZINC ION | 著者 | Nakamura, T, Kashima, Y, Mine, S, Oku, T, Uegaki, K. | 登録日 | 2012-02-21 | 公開日 | 2012-06-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Characterization and crystal structure of the thermophilic ROK hexokinase from Thermus thermophilus J.Biosci.Bioeng., 2012
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7EF9
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![BU of 7ef9 by Molmil](/molmil-images/mine/7ef9) | Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form II) | 分子名称: | Adenine DNA glycosylase, DNA (5'-D(*AP*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), ... | 著者 | Nakamura, T, Nakabeppu, Y, Yamagata, Y. | 登録日 | 2021-03-21 | 公開日 | 2021-06-23 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
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7EF8
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![BU of 7ef8 by Molmil](/molmil-images/mine/7ef8) | Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form I) | 分子名称: | Adenine DNA glycosylase, DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), ... | 著者 | Nakamura, T, Nakabeppu, Y, Yamagata, Y. | 登録日 | 2021-03-21 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
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7EFA
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3W6G
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![BU of 3w6g by Molmil](/molmil-images/mine/3w6g) | Structure of peroxiredoxin from anaerobic hyperthermophilic archaeon Pyrococcus horikoshii | 分子名称: | CITRATE ANION, Probable peroxiredoxin | 著者 | Nakamura, T, Mori, A, Niiyama, M, Matsumura, H, Tokuyama, C, Morita, J, Uegaki, K, Inoue, T. | 登録日 | 2013-02-14 | 公開日 | 2013-07-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of peroxiredoxin from the anaerobic hyperthermophilic archaeon Pyrococcus horikoshii Acta Crystallogr.,Sect.F, 69, 2013
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3AK1
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3AK3
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3VSA
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![BU of 3vsa by Molmil](/molmil-images/mine/3vsa) | Crystal Structure of O-phosphoserine sulfhydrylase without acetate | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, PYRIDOXAL-5'-PHOSPHATE, Protein CysO | 著者 | Nakamura, T, Kawai, Y, Kataoka, M, Ishikawa, K. | 登録日 | 2012-04-24 | 公開日 | 2012-05-16 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structural analysis of the substrate recognition mechanism in O-phosphoserine sulfhydrylase from the hyperthermophilic archaeon Aeropyrum pernix K1 J.Mol.Biol., 422, 2012
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3VSC
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![BU of 3vsc by Molmil](/molmil-images/mine/3vsc) | Crystal Structure of the K127A Mutant of O-Phosphoserine Sulfhydrylase Complexed with External Schiff Base of Pyridoxal 5'-Phosphate with O-Phospho-L-Serine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHOSERINE, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Nakamura, T, Kawai, Y, Kataoka, M, Ishikawa, K. | 登録日 | 2012-04-24 | 公開日 | 2012-05-16 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structural analysis of the substrate recognition mechanism in O-phosphoserine sulfhydrylase from the hyperthermophilic archaeon Aeropyrum pernix K1 J.Mol.Biol., 422, 2012
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3VSD
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![BU of 3vsd by Molmil](/molmil-images/mine/3vsd) | Crystal Structure of the K127A Mutant of O-Phosphoserine Sulfhydrylase Complexed with External Schiff Base of Pyridoxal 5'-Phosphate with O-Acetyl-L-Serine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, O-ACETYLSERINE, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Nakamura, T, Kawai, Y, Kataoka, M, Ishikawa, K. | 登録日 | 2012-04-24 | 公開日 | 2012-05-16 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural analysis of the substrate recognition mechanism in O-phosphoserine sulfhydrylase from the hyperthermophilic archaeon Aeropyrum pernix K1 J.Mol.Biol., 422, 2012
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6LCS
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![BU of 6lcs by Molmil](/molmil-images/mine/6lcs) | Crystal structure of 73MuL9 Fv-clasp fragment in complex with GA-pyridine analogue | 分子名称: | (2~{S})-6-[4-(hydroxymethyl)-3-oxidanyl-pyridin-1-ium-1-yl]-2-(phenylmethoxycarbonylamino)hexanoic acid, PHOSPHATE ION, VH-SARAH, ... | 著者 | Nakamura, T, Takagi, J, Yamagata, Y, Morioka, H. | 登録日 | 2019-11-19 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular recognition of a single-chain Fv antibody specific for GA-pyridine, an advanced glycation end-product (AGE), elucidated using biophysical techniques and synthetic antigen analogues. J.Biochem., 170, 2021
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5B36
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![BU of 5b36 by Molmil](/molmil-images/mine/5b36) | Crystal Structure of the O-Phosphoserine Sulfhydrylase from Aeropyrum pernix Complexed with Cysteine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CYSTEINE, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Nakamura, T, Takeda, E, Kawai, Y, Kataoka, M, Ishikawa, K. | 登録日 | 2016-02-10 | 公開日 | 2016-03-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Role of F225 in O-phosphoserine sulfhydrylase from Aeropyrum pernix K1 Extremophiles, 20, 2016
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5B3A
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![BU of 5b3a by Molmil](/molmil-images/mine/5b3a) | Crystal Structure of O-Phoshoserine Sulfhydrylase from Aeropyrum pernix in Complexed with the alpha-Aminoacrylate Intermediate | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Protein CysO | 著者 | Nakamura, T, Takeda, E, Kawai, Y, Kataoka, M, Ishikawa, K. | 登録日 | 2016-02-12 | 公開日 | 2016-03-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Role of F225 in O-phosphoserine sulfhydrylase from Aeropyrum pernix K1 Extremophiles, 20, 2016
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5WS7
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![BU of 5ws7 by Molmil](/molmil-images/mine/5ws7) | Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 2-oxo-dATP | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | 著者 | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | 登録日 | 2016-12-05 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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5GHJ
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![BU of 5ghj by Molmil](/molmil-images/mine/5ghj) | Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | 著者 | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | 登録日 | 2016-06-20 | 公開日 | 2017-01-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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