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2YQ7
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Structure of Bcl-xL bound to BimLOCK
分子名称: BCL-2-LIKE PROTEIN 1, BCL-2-LIKE PROTEIN 11, GLYCEROL
著者Smith, B.J, Czabotar, P.E.
登録日2012-11-06
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Stabilizing the Pro-Apoptotic Bimbh3 Helix (Bimsahb) Does not Necessarily Enhance Affinity or Biological Activity.
Acs Chem.Biol., 8, 2013
2YQ6
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BU of 2yq6 by Molmil
Structure of Bcl-xL bound to BimSAHB
分子名称: BCL-2-LIKE PROTEIN 1, BIM BETA 5, GLYCEROL
著者Smith, B.J, Czabotar, P.E.
登録日2012-11-06
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Stabilizing the Pro-Apoptotic Bimbh3 Helix (Bimsahb) Does not Necessarily Enhance Affinity or Biological Activity.
Acs Chem.Biol., 8, 2013
7Y6L
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BU of 7y6l by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab816
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab816 heavy chain, Ab816 light chain, ...
著者Uchikubo, T, Shirouzu, M.
登録日2022-06-21
公開日2023-06-21
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
7Y6N
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BU of 7y6n by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab803
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab803 heavy chain, Ab803 light chain, ...
著者Uchikubo, T, Shirouzu, M.
登録日2022-06-21
公開日2023-06-21
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
8K9O
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BU of 8k9o by Molmil
Crystal structure of Cyanobacteriochrome RcaE GAF domain in Pg state
分子名称: PHYCOCYANOBILIN, histidine kinase
著者Nagae, T, Hirose, Y, Mishima, M.
登録日2023-08-01
公開日2024-05-15
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Green/red light-sensing mechanism in the chromatic acclimation photosensor.
Sci Adv, 10, 2024
1WDV
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BU of 1wdv by Molmil
Crystal structure of hypothetical protein APE2540
分子名称: hypothetical protein APE2540
著者Murayama, K, Kato-Murayama, M, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-18
公開日2004-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of a putative trans-editing enzyme for prolyl-tRNA synthetase from Aeropyrum pernix K1 at 1.7 A resolution.
Acta Crystallogr.,Sect.F, 61, 2005
8JG5
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BU of 8jg5 by Molmil
Cryo-EM structure of the GI.4 Chiba VLP complexed with the CV-1A1 Fv-clasp
分子名称: VH,SARAH, VL,SARAH, VP1
著者Hosaka, T, Katsura, K, Kimura-Someya, T, Someya, Y, Shirouzu, M.
登録日2023-05-19
公開日2024-04-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Structural analyses of the GI.4 norovirus by cryo-electron microscopy and X-ray crystallography revealing binding sites for human monoclonal antibodies.
J.Virol., 98, 2024
7X93
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BU of 7x93 by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab765
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab765 heavy chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
7X95
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BU of 7x95 by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab709
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab709 heavy chain, Ab709 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
7X94
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BU of 7x94 by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab712
分子名称: Ab712 heavy chain, Ab712 light chain, Spike glycoprotein, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
7X96
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BU of 7x96 by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab847
分子名称: Ab847 heavy chain, Ab847 light chain, Spike glycoprotein, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
8I5L
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BU of 8i5l by Molmil
Crystal structure of P domain from norovirus GI.4 capsid protein in complex with broad specificity antibody single-chain Fv fragment CV-2F5.
分子名称: Capsid protein, scFv fragment
著者Kato-Murayama, M, Murayama, K, Shirouzu, M.
登録日2023-01-26
公開日2024-01-31
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analyses of the GI.4 norovirus by cryo-electron microscopy and X-ray crystallography revealing binding sites for human monoclonal antibodies.
J.Virol., 98, 2024
7X91
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BU of 7x91 by Molmil
The SARS-CoV-2 receptor binding domain bound with an Fv-clasp form of a human neutralizing antibody Ab496
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, An Fv-clasp version of the Ab496 heavy chain, An Fv-clasp version of the Ab496 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X8Z
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BU of 7x8z by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab188
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab188 heavy chain, Ab188 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X8W
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BU of 7x8w by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab354
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab354 heavy chain, Ab354 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X8Y
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BU of 7x8y by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab159
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab159 heavy chain, Ab159 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X90
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BU of 7x90 by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab326
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab326 heavy chain, Ab326 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X92
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BU of 7x92 by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab445
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab445 heavy chain, Ab445 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7DKJ
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BU of 7dkj by Molmil
Hemagglutinin Influenza A virus (A/Okuda/1957(H2N2) bound with a neutralizing antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fv-clasp heavy chain, Fv-clasp light chain, ...
著者Shirouzu, M.
登録日2020-11-24
公開日2021-11-24
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Hemagglutinin Influenza A virus (A/Okuda/1957(H2N2) bound with a neutralizing antibody
To Be Published
2CZL
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BU of 2czl by Molmil
Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8 (Cys11 modified with beta-mercaptoethanol)
分子名称: 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, L(+)-TARTARIC ACID, POTASSIUM ION, ...
著者Arai, R, Nishino, A, Nagano, K, Kamo-Uchikubo, T, Nishimoto, M, Toyama, M, Terada, T, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-13
公開日2006-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8.
J.Struct.Biol., 168, 2009
3WG8
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BU of 3wg8 by Molmil
Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist AS6
分子名称: (2Z,4E)-5-[(1S)-3-(hexylsulfanyl)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYR1
著者Akiyama, T, Sue, M, Takeuchi, J, Okamoto, M, Muto, T, Endo, A, Nambara, E, Hirai, N, Ohnishi, T, Cutler, S.R, Todoroki, Y, Yajima, S.
登録日2013-07-31
公開日2014-05-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Designed abscisic acid analogs as antagonists of PYL-PP2C receptor interactions
Nat.Chem.Biol., 10, 2014
7CKV
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BU of 7ckv by Molmil
Crystal structure of Cyanobacteriochrome GAF domain in Pr state
分子名称: MAGNESIUM ION, PHYCOCYANOBILIN, RcaE
著者Nagae, T, Koizumi, T, Hirose, Y, Mishima, M.
登録日2020-07-19
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural basis of the protochromic green/red photocycle of the chromatic acclimation sensor RcaE.
Proc.Natl.Acad.Sci.USA, 118, 2021
2YV6
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BU of 2yv6 by Molmil
Crystal structure of human Bcl-2 family protein Bak
分子名称: Bcl-2 homologous antagonist/killer, SULFATE ION
著者Wang, H, Kishishita, S, Murayama, K, Takemoto, C, Terada, T, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-09
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Novel dimerization mode of the human Bcl-2 family protein Bak, a mitochondrial apoptosis regulator.
J.Struct.Biol., 166, 2009
2ZMF
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BU of 2zmf by Molmil
Crystal structure of the C-terminal GAF domain of human phosphodiesterase 10A
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
著者Handa, N, Kishishita, S, Mizohata, E, Omori, K, Kotera, J, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-04-17
公開日2008-04-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the GAF-B Domain from Human Phosphodiesterase 10A Complexed with Its Ligand, cAMP
J.Biol.Chem., 283, 2008
3WEX
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BU of 3wex by Molmil
Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen
著者Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S.
登録日2013-07-16
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5
J. Mol. Biol., 426, 2014

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