3WG8

Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist AS6

Summary for 3WG8

Entry DOI	10.2210/pdb3wg8/pdb
Descriptor	Abscisic acid receptor PYR1, (2Z,4E)-5-[(1S)-3-(hexylsulfanyl)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid (3 entities in total)
Functional Keywords	abscisic acid, hormone receptor
Biological source	Arabidopsis thaliana (mouse-ear cress)
Cellular location	Cytoplasm (By similarity): O49686
Total number of polymer chains	1
Total formula weight	25813.03
Authors	Akiyama, T.,Sue, M.,Takeuchi, J.,Okamoto, M.,Muto, T.,Endo, A.,Nambara, E.,Hirai, N.,Ohnishi, T.,Cutler, S.R.,Todoroki, Y.,Yajima, S. (deposition date: 2013-07-31, release date: 2014-05-07, Last modification date: 2023-11-08)
Primary citation	Takeuchi, J.,Okamoto, M.,Akiyama, T.,Muto, T.,Yajima, S.,Sue, M.,Seo, M.,Kanno, Y.,Kamo, T.,Endo, A.,Nambara, E.,Hirai, N.,Ohnishi, T.,Cutler, S.R.,Todoroki, Y. Designed abscisic acid analogs as antagonists of PYL-PP2C receptor interactions Nat.Chem.Biol., 10:477-482, 2014 Cited by PubMed: 24792952 DOI: 10.1038/nchembio.1524 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation