3WG8

Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist AS6

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004864	molecular_function	protein phosphatase inhibitor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005773	cellular_component	vacuole
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0009705	cellular_component	plant-type vacuole membrane
A	0009738	biological_process	abscisic acid-activated signaling pathway
A	0010427	molecular_function	abscisic acid binding
A	0038023	molecular_function	signaling receptor activity
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0044389	molecular_function	ubiquitin-like protein ligase binding
A	0062049	cellular_component	protein phosphatase inhibitor complex
A	0080163	biological_process	regulation of protein serine/threonine phosphatase activity
A	1902584	biological_process	positive regulation of response to water deprivation

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 6AS A 201

Chain	Residue
A	LYS59
A	GLU141
A	PHE159
A	VAL163
A	HOH311
A	HOH316
A	SER85
A	LEU87
A	ALA89
A	SER92
A	PHE108
A	ILE110
A	LEU117
A	TYR120

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:19898494, ECO:0000269|PubMed:19933100

Chain	Residue	Details
A	LYS59
A	ALA89
A	ARG116
A	GLU141

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Involved in interactions with PP2Cs => ECO:0000269|PubMed:19407142

Chain	Residue	Details
A	PRO88
A	SER152

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by CARK1 => ECO:0000269|PubMed:29928509

Chain	Residue	Details
A	THR78

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