7V3S
| Crystal structure of CMET in complex with a novel inhibitor | 分子名称: | Hepatocyte growth factor receptor, ~{N}1'-[3-fluoranyl-4-(10~{H}-pyrido[3,2-b][1,4]benzoxazin-4-yloxy)phenyl]-~{N}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | 著者 | Su, H.X, Liu, Q.F, Chen, T.T, Li, M.J, Xu, Y.C. | 登録日 | 2021-08-11 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase J.Med.Chem., 66, 2023
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8H41
| Crystal structure of a decarboxylase from Trichosporon moniliiforme in complex with o-nitrophenol | 分子名称: | MAGNESIUM ION, O-NITROPHENOL, Salicylate decarboxylase | 著者 | Gao, J, Zhao, Y.P, Li, Q, Liu, W.D, Sheng, X. | 登録日 | 2022-10-09 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | A Combined Computational-Experimental Study on the Substrate Binding and Reaction Mechanism of Salicylic Acid Decarboxylase Catalysts, 12, 2022
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7VS2
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7W1S
| Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-007 | 分子名称: | Nanobody Nb-007, Spike protein S1 | 著者 | Yang, J, Lin, S, Sun, H.L, Lu, G.W. | 登録日 | 2021-11-20 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | A Potent Neutralizing Nanobody Targeting the Spike Receptor-Binding Domain of SARS-CoV-2 and the Structural Basis of Its Intimate Binding. Front Immunol, 13, 2022
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7XS0
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7XS2
| Monomer structure of HtrA from Helicobacter pylori | 分子名称: | Periplasmic serine endoprotease DegP-like | 著者 | Cui, L, Liu, W. | 登録日 | 2022-05-12 | 公開日 | 2023-05-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structures and solution conformations of HtrA from Helicobacter pylori reveal pH-dependent oligomeric conversion and conformational rearrangements. Int.J.Biol.Macromol., 243, 2023
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8I8F
| Crystal structure of NDM-1 at pH5.5 (Succinate) in complex with hydrolyzed compound 1 | 分子名称: | (2R,4S)-5,5-dimethyl-2-[(1R)-1-(2-naphthalen-1-yloxyethanoylamino)-2-oxidanyl-2-oxidanylidene-ethyl]-1,3-thiazolidine-4-carboxylic acid, Metallo beta lactamase NDM-1, ZINC ION | 著者 | Shi, X, Liu, W. | 登録日 | 2023-02-04 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Interplay between the beta-lactam side chain and an active-site mobile loop of NDM-1 in penicillin hydrolysis as a potential target for mechanism-based inhibitor design. Int.J.Biol.Macromol., 262, 2024
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6AIT
| Crystal structure of E. coli BepA | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-barrel assembly-enhancing protease, ZINC ION | 著者 | Umar, M.S.M, Tanaka, Y, Kamikubo, H, Tsukazaki, T. | 登録日 | 2018-08-24 | 公開日 | 2018-12-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | 主引用文献 | Structural Basis for the Function of the beta-Barrel Assembly-Enhancing Protease BepA. J. Mol. Biol., 431, 2019
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1R1X
| Crystal structure of oxy-human hemoglobin Bassett at 2.15 angstrom | 分子名称: | CARBON MONOXIDE, Hemoglobin alpha chain, Hemoglobin beta chain, ... | 著者 | Abdulmalik, O, Safo, M.K, Lerner, N.B, Ochotorena, J, Dhaikin, Y, Abraham, D.J, Asakura, T. | 登録日 | 2003-09-25 | 公開日 | 2003-10-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Characterization of hemoglobin bassett (alpha94Asp-->Ala), a variant with very low oxygen affinity Am.J.Hematol., 77, 2004
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1R1Y
| Crystal structure of deoxy-human hemoglobin Bassett at 1.8 angstrom | 分子名称: | Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Abdulmalik, O, Safo, M.K, Lerner, N.B, Ochotorena, J, Dhaikin, Y, Abraham, D.J, Asakura, T. | 登録日 | 2003-09-25 | 公開日 | 2003-10-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Characterization of hemoglobin bassett (alpha94Asp-->Ala), a variant with very low oxygen affinity Am.J.Hematol., 77, 2004
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7YAG
| CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 1 | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7YAH
| CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 2 | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7YAI
| CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 3 | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, Nanobody head piece of megabody, ... | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7YAJ
| CryoEM structure of SPCA1a in E1-Mn-AMPPCP state subclass 1 | 分子名称: | Calcium-transporting ATPase type 2C member 1, MANGANESE (II) ION, Nanobody head piece of megabody, ... | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7YAM
| CryoEM structure of SPCA1a in E2P state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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