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7N8E
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BU of 7n8e by Molmil
PptT PAP(CoA) 9056 complex
分子名称: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
著者Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2021-06-14
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
7N8M
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PptT PAP(CoA) 8978B complex
分子名称: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
著者Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2021-06-15
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
1XXU
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Crystal Structure of AhpE from Mycrobacterium tuberculosis, a 1-Cys peroxiredoxin
分子名称: Hypothetical protein Rv2238c/MT2298
著者Li, S, Peterson, N.A, Kim, M.Y, Kim, C.Y, Hung, L.W, Yu, M, Lekin, T, Segelke, B.W, Lott, J.S, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
登録日2004-11-08
公開日2005-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys Peroxiredoxin
J.Mol.Biol., 346, 2005
1XXX
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BU of 1xxx by Molmil
Crystal structure of Dihydrodipicolinate Synthase (DapA, Rv2753c) from Mycobacterium tuberculosis
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, Dihydrodipicolinate synthase, ...
著者Kefala, G, Panjikar, S, Janowski, R, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2004-11-09
公開日2006-02-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.
Biochem.J., 411, 2008
1YK9
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Crystal structure of a mutant form of the mycobacterial adenylyl cyclase Rv1625c
分子名称: Adenylate cyclase
著者Ketkar, A.D, Shenoy, A.R, Ramagopal, U.A, Visweswariah, S.S, Suguna, K, TB Structural Genomics Consortium (TBSGC)
登録日2005-01-17
公開日2006-01-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Structural Basis for the Role of Nucleotide Specifying Residues in Regulating the Oligomerization of the Rv1625c Adenylyl Cyclase from M.tuberculosis
J.Mol.Biol., 356, 2006
1W0D
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The high resolution structure of Mycobacterium tuberculosis LeuB (Rv2995c)
分子名称: 3-ISOPROPYLMALATE DEHYDROGENASE, SULFATE ION
著者Singh, R.K, Kefala, G, Janowski, R, Mueller-Dieckmann, C, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2004-06-03
公開日2004-12-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The High Resolution Structure of Leub (Rv2995C) from Mycobacterium Tuberculosis
J.Mol.Biol., 346, 2005
1Y30
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X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with flavin mononucleotide at 2.2 a resolution
分子名称: FLAVIN MONONUCLEOTIDE, hypothetical protein Rv1155
著者Biswal, B.K, Cherney, M.M, Wang, M, Garen, C, James, M.N, TB Structural Genomics Consortium (TBSGC)
登録日2004-11-23
公開日2005-08-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.D, 61, 2005
4M2X
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Mycobacterium tuberculosis dihydrofolate reductase complexed with trimetrexate (TMQ)
分子名称: ACETATE ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Jung, H, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2013-08-05
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Selective inhibitors for dihydrofolate reductase from mycobacterium tuberculosis
To be Published
1VS0
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Crystal Structure of the Ligase Domain from M. tuberculosis LigD at 2.4A
分子名称: CHLORIDE ION, MAGNESIUM ION, Putative DNA ligase-like protein Rv0938/MT0965, ...
著者Akey, D, Martins, A, Aniukwu, J, Glickman, M.S, Shuman, S, Berger, J.M, TB Structural Genomics Consortium (TBSGC)
登録日2006-01-27
公開日2006-02-28
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure and Nonhomologous End-joining Function of the Ligase Component of Mycobacterium DNA Ligase D.
J.Biol.Chem., 281, 2006
1VA5
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Antigen 85C with octylthioglucoside in active site
分子名称: Antigen 85-C, octyl 1-thio-beta-D-glucopyranoside
著者Ronning, D.R, Vissa, V, Besra, G.S, Belisle, J.T, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2004-02-11
公開日2004-07-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Mycobacterium tuberculosis Antigen 85A and 85C Structures Confirm Binding Orientation and Conserved Substrate Specificity
J.Biol.Chem., 279, 2004
1XXO
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X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase at 1.8 a resolution
分子名称: hypothetical protein Rv1155
著者Biswal, B.K, Cherney, M.M, Wang, M, Garen, C, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2004-11-07
公開日2004-11-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase at 1.8 a resolution
To be Published
1Y6X
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The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis
分子名称: Phosphoribosyl-ATP pyrophosphatase
著者Javid-Majd, F, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2004-12-07
公開日2005-03-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
1YL6
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crystal structure of Mycobacterium tuberculosis dihydrodipicolinate reductase (Rv2773c) (crystal form B)
分子名称: Dihydrodipicolinate reductase, MAGNESIUM ION
著者Janowski, R, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2005-01-19
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure of dihydrodipicolinate reductase (DapB) from Mycobacterium tuberculosis in three crystal forms.
Acta Crystallogr.,Sect.D, 66, 2010
1YL5
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Crystal structure of Mycobacterium tuberculosis dihydrodipicolinate reductase (RV2773C) (crystal form A)
分子名称: Dihydrodipicolinate reductase, MAGNESIUM ION
著者Janowski, R, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2005-01-19
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of dihydrodipicolinate reductase (DapB) from Mycobacterium tuberculosis in three crystal forms.
Acta Crystallogr.,Sect.D, 66, 2010
1YK3
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Crystal structure of Rv1347c from Mycobacterium tuberculosis
分子名称: Hypothetical protein Rv1347c/MT1389, octyl beta-D-glucopyranoside
著者Card, G.L, Peterson, N.A, Smith, C.A, Rupp, B, Schick, B.M, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
登録日2005-01-16
公開日2005-02-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of Rv1347c, a putative antibiotic resistance protein from Mycobacterium tuberculosis, reveals a GCN5-related fold and suggests an alternative function in siderophore biosynthesis
J.Biol.Chem., 280, 2005
5UA1
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Mycobacterium tuberculosis KstR in complex with a 18-bp DNA operator
分子名称: DNA (5'-D(*AP*CP*TP*AP*GP*AP*AP*CP*GP*TP*GP*TP*TP*CP*TP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*AP*GP*AP*AP*CP*AP*CP*GP*TP*TP*CP*TP*AP*GP*T)-3'), HTH-type transcriptional repressor KstR, ...
著者Ho, N.A.T, Dawes, S.S, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2016-12-18
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of KstR in complex with cognate DNA operator
To Be Published
1Y8T
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Crystal Structure of RV0983 from Mycobacterium tuberculosis- Proteolytically active form
分子名称: hypothetical protein Rv0983
著者Palaninathan, S.K, MohamedMohaideen, N.N, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2004-12-13
公開日2005-01-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Possible role for HtrA homologs in mycobacterium tuberculosis
To be Published
6UNC
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The crystal structure of Phosphopantetheinyl Hydrolase (PptH) from Mycobacterium tuberculosis
分子名称: FE (III) ION, MANGANESE (II) ION, Metallophos domain-containing protein
著者Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2019-10-11
公開日2020-04-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis.
Protein Sci., 29, 2020
1EYV
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THE CRYSTAL STRUCTURE OF NUSB FROM MYCOBACTERIUM TUBERCULOSIS
分子名称: N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG, PHOSPHATE ION
著者Gopal, B, Haire, L.F, Cox, R.A, Colston, M.J, Major, S, Brannigan, J.A, Smerdon, S.J, Dodson, G.G, TB Structural Genomics Consortium (TBSGC)
登録日2000-05-09
公開日2000-05-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of NusB from Mycobacterium tuberculosis.
Nat.Struct.Biol., 7, 2000
1F0P
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MYCOBACTERIUM TUBERCULOSIS ANTIGEN 85B WITH TREHALOSE
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANTIGEN 85-B, ...
著者Anderson, D.H, Harth, G, Horwitz, M.A, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2000-05-16
公開日2001-01-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase.
J.Mol.Biol., 307, 2001
1G18
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RECA-ADP-ALF4 COMPLEX
分子名称: ADENOSINE-5'-DIPHOSPHATE, RECA PROTEIN, TETRAFLUOROALUMINATE ION
著者Datta, S, Prabu, M.M, Vaze, M.B, Ganesh, N, Chandra, N.R, Muniyappa, K, Vijayan, M, TB Structural Genomics Consortium (TBSGC)
登録日2000-10-11
公開日2000-12-11
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal structures of Mycobacterium tuberculosis RecA and its complex with ADP-AlF(4): implications for decreased ATPase activity and molecular aggregation
Nucleic Acids Res., 28, 2000
1G19
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STRUCTURE OF RECA PROTEIN
分子名称: PHOSPHATE ION, RECA PROTEIN
著者Datta, S, Prabu, M.M, Vaze, M.B, Ganesh, N, Chandra, N.R, Muniyappa, K, Vijayan, M, TB Structural Genomics Consortium (TBSGC)
登録日2000-10-11
公開日2000-12-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of Mycobacterium tuberculosis RecA and its complex with ADP-AlF(4): implications for decreased ATPase activity and molecular aggregation
Nucleic Acids Res., 28, 2000
1DQY
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CRYSTAL STRUCTURE OF ANTIGEN 85C FROM MYCOBACTERIUM TUBERCULOSIS WITH DIETHYL PHOSPHATE INHIBITOR
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, DIETHYL PHOSPHONATE, PROTEIN (ANTIGEN 85-C)
著者Ronning, D.R, Klabunde, T, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2000-01-05
公開日2000-07-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines.
Nat.Struct.Biol., 7, 2000
1F0N
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MYCOBACTERIUM TUBERCULOSIS ANTIGEN 85B
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANTIGEN 85B
著者Anderson, D.H, Harth, G, Horwitz, M.A, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2000-05-16
公開日2001-01-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase.
J.Mol.Biol., 307, 2001
1F61
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CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称: ISOCITRATE LYASE, MAGNESIUM ION
著者Sharma, V, Sharma, S, Hoener zu Bentrup, K.H, McKinney, J.D, Russell, D.G, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2000-06-19
公開日2000-08-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis.
Nat.Struct.Biol., 7, 2000

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