1S2W
| Crystal structure of phosphoenolpyruvate mutase in high ionic strength | 分子名称: | Phosphoenolpyruvate phosphomutase, SULFATE ION | 著者 | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | 登録日 | 2004-01-11 | 公開日 | 2004-05-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Conformational Flexibility of PEP Mutase Biochemistry, 43, 2004
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1S2T
| Crystal Structure Of Apo Phosphoenolpyruvate Mutase | 分子名称: | Phosphoenolpyruvate phosphomutase | 著者 | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | 登録日 | 2004-01-11 | 公開日 | 2004-05-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformational Flexibility of PEP Mutase Biochemistry, 43, 2004
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1S2V
| Crystal structure of phosphoenolpyruvate mutase complexed with Mg(II) | 分子名称: | MAGNESIUM ION, Phosphoenolpyruvate phosphomutase | 著者 | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | 登録日 | 2004-01-11 | 公開日 | 2004-05-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformational Flexibility of PEP Mutase Biochemistry, 43, 2004
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8EQB
| FAM46C/BCCIPalpha/Nanobody complex | 分子名称: | Isoform 2 of BRCA2 and CDKN1A-interacting protein, Synthetic nanobody 1, Terminal nucleotidyltransferase 5C | 著者 | Liu, S, Chen, H, Yin, Y, Bai, X, Zhang, X. | 登録日 | 2022-10-07 | 公開日 | 2023-03-15 | 最終更新日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Inhibition of FAM46/TENT5 activity by BCCIP alpha adopting a unique fold. Sci Adv, 9, 2023
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8EXF
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8EXE
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4ZP5
| MAP4K4 in complex with inhibitor | 分子名称: | 4-[5-(4-chlorophenyl)-1,3-oxazol-2-yl]benzamide, Mitogen-activated protein kinase kinase kinase kinase 4 | 著者 | Liu, S. | 登録日 | 2015-05-07 | 公開日 | 2016-10-05 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structure of MAP4K4 complex To Be Published
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6CPV
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2LVN
| Structure of the gp78 CUE domain | 分子名称: | E3 ubiquitin-protein ligase AMFR | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | 登録日 | 2012-07-09 | 公開日 | 2012-11-21 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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2LVP
| gp78CUE domain bound to the distal ubiquitin of K48-linked diubiquitin | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | 登録日 | 2012-07-09 | 公開日 | 2012-11-21 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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2LVQ
| gp78CUE domain bound to the proximal ubiquitin of K48-linked diubiquitin | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | 登録日 | 2012-07-09 | 公開日 | 2012-11-21 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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3EB1
| Crystal structure PTP1B complex with small molecule inhibitor LZP-25 | 分子名称: | 4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Liu, S, Zheng, L.-F, Wu, L, Yu, X, Xue, T, Gunawan, A.M, Long, Y.-Q, Zhang, Z.-Y. | 登録日 | 2008-08-26 | 公開日 | 2009-07-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors. J.Am.Chem.Soc., 130, 2008
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3DYL
| human phosphdiesterase 9 substrate complex (ES complex) | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, CYCLIC GUANOSINE MONOPHOSPHATE, FORMIC ACID, ... | 著者 | Liu, S, Mansour, M.N, Dillman, K, Perez, J, Danley, D, Menniti, F. | 登録日 | 2008-07-28 | 公開日 | 2008-09-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for the catalytic mechanism of human phosphodiesterase 9. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2OZB
| Structure of a human Prp31-15.5K-U4 snRNA complex | 分子名称: | CALCIUM ION, RNA comprising the 5' Stem-Loop RNA of U4snRNA, U4/U6 small nuclear ribonucleoprotein Prp31, ... | 著者 | Liu, S, Luehrmann, R, Wahl, M.C. | 登録日 | 2007-02-26 | 公開日 | 2007-03-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP. Science, 316, 2007
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3DYQ
| human phosphodiestrase 9 (inhibited by omitting divalent cation) in complex with cGMP | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, CYCLIC GUANOSINE MONOPHOSPHATE, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ... | 著者 | Liu, S, Mansour, M.N, Dillman, K, Perez, J, Danley, D, Menniti, F. | 登録日 | 2008-07-28 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the catalytic mechanism of human phosphodiesterase 9. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3DY8
| Human Phosphodiesterase 9 in complex with product 5'-GMP (E+P complex) | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, FORMIC ACID, GUANOSINE-5'-MONOPHOSPHATE, ... | 著者 | Liu, S, Mansour, M.N, Dillman, K, Perez, J, Danley, D, Menniti, F. | 登録日 | 2008-07-25 | 公開日 | 2008-09-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for the catalytic mechanism of human phosphodiesterase 9. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3DYN
| human phosphodiestrase 9 in complex with cGMP (Zn inhibited) | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, CYCLIC GUANOSINE MONOPHOSPHATE, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ... | 著者 | Liu, S, Mansour, M.N, Dillman, K, Perez, J, Danley, D, Menniti, F. | 登録日 | 2008-07-28 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for the catalytic mechanism of human phosphodiesterase 9. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3DYS
| human phosphodiestrase-5'GMP complex (EP), produced by soaking with 20mM cGMP+20 mM MnCl2+20 mM MgCl2 for 2 hours, and flash-cooled to liquid nitrogen temperature when substrate was still abudant. | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, FORMIC ACID, GUANOSINE-5'-MONOPHOSPHATE, ... | 著者 | Liu, S, Mansour, M.N, Dillman, K, Perez, J, Danley, D, Menniti, F. | 登録日 | 2008-07-28 | 公開日 | 2008-09-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for the catalytic mechanism of human phosphodiesterase 9. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2LVO
| Structure of the gp78CUE domain bound to monubiquitin | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | 登録日 | 2012-07-09 | 公開日 | 2012-11-21 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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4DHY
| Crystal structure of human glucokinase in complex with glucose and activator | 分子名称: | Glucokinase, N,N-dimethyl-5-({2-methyl-6-[(5-methylpyrazin-2-yl)carbamoyl]-1-benzofuran-4-yl}oxy)pyrimidine-2-carboxamide, SODIUM ION, ... | 著者 | Liu, S. | 登録日 | 2012-01-30 | 公開日 | 2012-02-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS. J.Biol.Chem., 287, 2012
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4EWS
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6KKU
| human KCC1 structure determined in NaCl and GDN | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | 登録日 | 2019-07-27 | 公開日 | 2019-10-23 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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6KKT
| human KCC1 structure determined in KCl and lipid nanodisc | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | 登録日 | 2019-07-27 | 公開日 | 2019-10-23 | 最終更新日 | 2020-08-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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6KKR
| human KCC1 structure determined in KCl and detergent GDN | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | 登録日 | 2019-07-27 | 公開日 | 2019-10-23 | 最終更新日 | 2020-08-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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5BX1
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