1ZR0
| Crystal Structure of Kunitz Domain 1 of Tissue Factor Pathway Inhibitor-2 with Bovine Trypsin | 分子名称: | CALCIUM ION, Cationic trypsin, Tissue factor pathway inhibitor 2 | 著者 | Schmidt, A.E, Chand, H.S, Cascio, D, Kisiel, W, Bajaj, S.P. | 登録日 | 2005-05-18 | 公開日 | 2005-06-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition J.Biol.Chem., 280, 2005
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6P0U
| Crystal structure of ternary DNA complex " FX(1-2)-2Xis" containing E. coli Fis and phage lambda Xis | 分子名称: | DNA (27-MER), FX1-2, DNA-binding protein Fis, ... | 著者 | Hancock, S.P, Cascio, D, Johnson, R.C. | 登録日 | 2019-05-17 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res., 47, 2019
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6PIL
| Antibody scFv-M204 monomeric state | 分子名称: | CHLORIDE ION, scFv-M204 antibody | 著者 | Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. | 登録日 | 2019-06-26 | 公開日 | 2020-06-24 | 最終更新日 | 2020-08-12 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J.Biol.Chem., 295, 2020
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7MPK
| Crystal structure of TagA with UDP-GlcNAc | 分子名称: | N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | 著者 | Martinez, O.E, Cascio, D, Clubb, R.T. | 登録日 | 2021-05-04 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.993 Å) | 主引用文献 | Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA. J.Biol.Chem., 298, 2021
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6P0S
| Crystal structure of ternary DNA complex "FX2" containing E. coli Fis and phage lambda Xis | 分子名称: | DNA (27-MER), FX1-2, DNA-binding protein Fis, ... | 著者 | Hancock, S.P, Cascio, D, Johnson, R.C. | 登録日 | 2019-05-17 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res., 47, 2019
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1K26
| Structure of a Nudix Protein from Pyrobaculum aerophilum Solved by the Single Wavelength Anomolous Scattering Method | 分子名称: | ACETIC ACID, GLYCEROL, IRIDIUM (III) ION, ... | 著者 | Wang, S, Mura, C, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2001-09-26 | 公開日 | 2002-04-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallogr.,Sect.D, 58, 2002
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6PK8
| Antibody scFv-M204 dimeric state | 分子名称: | SULFATE ION, scFv-M204 antibody | 著者 | Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. | 登録日 | 2019-06-28 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J.Biol.Chem., 295, 2020
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5V5C
| VQIINK, Structure of the amyloid-spine from microtubule associated protein tau Repeat 2 | 分子名称: | Microtubule-associated protein tau | 著者 | Seidler, P.M, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S, Cascio, D, Boyer, D.R. | 登録日 | 2017-03-14 | 公開日 | 2018-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.25 Å) | 主引用文献 | Structure-based inhibitors of tau aggregation. Nat Chem, 10, 2018
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6PSC
| Antibody scFv-M204 trimeric state | 分子名称: | scFv-M204 antibody | 著者 | Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. | 登録日 | 2019-07-12 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J.Biol.Chem., 295, 2020
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5V5B
| KVQIINKKLD, Structure of the amyloid spine from microtubule associated protein tau Repeat 2 | 分子名称: | Microtubule-associated protein tau | 著者 | Seidler, P.M, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S, Cascio, D, Boyer, D.R. | 登録日 | 2017-03-13 | 公開日 | 2018-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.5 Å) | 主引用文献 | Structure-based inhibitors of tau aggregation. Nat Chem, 10, 2018
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1K2E
| crystal structure of a nudix protein from Pyrobaculum aerophilum | 分子名称: | ACETIC ACID, GLYCEROL, NICKEL (II) ION, ... | 著者 | Wang, S, Mura, C, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2001-09-26 | 公開日 | 2002-04-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallogr.,Sect.D, 58, 2002
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7SJY
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5VKZ
| Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies | 分子名称: | Mitochondrial distribution and morphology protein 12 | 著者 | Egea, P.F, AhYoung, A.P, Lu, B, Tan, H.R, Cascio, D. | 登録日 | 2017-04-24 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies. Biochem. Biophys. Res. Commun., 488, 2017
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2OG0
| Crystal Structure of the Lambda Xis-DNA complex | 分子名称: | 5'-D(*AP*AP*AP*CP*AP*GP*AP*CP*TP*AP*CP*AP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*TP*AP*TP*TP*AP*TP*GP*TP*AP*GP*TP*CP*TP*GP*TP*TP*T)-3', Excisionase | 著者 | Papagiannis, C.V, Sam, M.D, Abbani, M.A, Cascio, D, Yoo, D, Clubb, R.T, Johnson, R.C. | 登録日 | 2007-01-04 | 公開日 | 2007-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fis targets assembly of the xis nucleoprotein filament to promote excisive recombination by phage lambda. J.Mol.Biol., 367, 2007
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1YAC
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7N41
| Crystal structure of TagA with UDP-ManNAc | 分子名称: | (2R,3S,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name), N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase | 著者 | Martinez, O.E, Cascio, D, Clubb, R.T. | 登録日 | 2021-06-03 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA. J.Biol.Chem., 298, 2021
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1LMI
| 1.5 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS-MPT63 | 分子名称: | Immunogenic protein MPT63/MPB63 | 著者 | Goulding, C.W, Parseghian, A, Sawaya, M.R, Cascio, D, Apostol, M, Gennaro, M.L, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2002-05-01 | 公開日 | 2002-12-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at
1.5-A resolution Protein Sci., 11, 2002
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4MJH
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4D9J
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4EDI
| Disulfide bonded EutL from Clostridium perfringens | 分子名称: | Ethanolamine utilization protein, SODIUM ION | 著者 | Thompson, M.C, Cascio, D, Crowley, C.S, Kopstein, J.S, Yeates, T.O. | 登録日 | 2012-03-27 | 公開日 | 2013-03-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | An allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein. Protein Sci., 24, 2015
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4ERD
| Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 in complex with stem IV of telomerase RNA | 分子名称: | 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION, Telomerase associated protein p65 | 著者 | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | 登録日 | 2012-04-19 | 公開日 | 2012-06-20 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.589 Å) | 主引用文献 | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
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4M5S
| Human alphaB crystallin core domain in complex with C-terminal peptide | 分子名称: | Alpha-crystallin B chain, SUCCINIC ACID | 著者 | Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D. | 登録日 | 2013-08-08 | 公開日 | 2014-04-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity. Proc.Natl.Acad.Sci.USA, 111, 2014
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4EYT
| Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 | 分子名称: | SULFATE ION, Telomerase associated protein p65 | 著者 | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | 登録日 | 2012-05-01 | 公開日 | 2012-06-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
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4FDZ
| EutL from Clostridium perfringens, Crystallized Under Reducing Conditions | 分子名称: | Ethanolamine utilization protein, SODIUM ION | 著者 | Thompson, M.C, Cascio, D, Crowley, C.S, Kopstein, J.S, Yeates, T.O. | 登録日 | 2012-05-29 | 公開日 | 2013-05-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | An allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein. Protein Sci., 24, 2015
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4F6E
| Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Sheng, Y, Cascio, D, Valentine, J.S. | 登録日 | 2012-05-14 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae to be published
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