7Q9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q9m by Molmil](/molmil-images/mine/7q9m) | Beta-53 fab in complex with SARS-CoV-2 beta-Spike glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-53 fab heavy chain, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | 登録日 | 2021-11-12 | 公開日 | 2021-12-15 | 最終更新日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
|
|
7Q9P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q9p by Molmil](/molmil-images/mine/7q9p) | Beta-06 fab in complex with SARS-CoV-2 beta-Spike glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-06 heavy chain, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | 登録日 | 2021-11-12 | 公開日 | 2021-12-15 | 最終更新日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
|
|
5TBN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tbn by Molmil](/molmil-images/mine/5tbn) | |
2KIA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kia by Molmil](/molmil-images/mine/2kia) | Solution structure of Myosin VI C-terminal cargo-binding domain | 分子名称: | Myosin-VI | 著者 | Feng, W, Yu, C, Wei, Z, Miyanoiri, Y, Zhang, M. | 登録日 | 2009-04-29 | 公開日 | 2009-09-29 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Myosin VI undergoes cargo-mediated dimerization Cell(Cambridge,Mass.), 138, 2009
|
|
4PS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ps4 by Molmil](/molmil-images/mine/4ps4) | Crystal structure of the complex between IL-13 and M1295 FAB | 分子名称: | Interleukin-13, M1295 HEAVY CHAIN, M1295 LIGHT CHAIN | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | 登録日 | 2014-03-06 | 公開日 | 2014-03-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody. J.Mol.Biol., 398, 2010
|
|
4DJG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4djg by Molmil](/molmil-images/mine/4djg) | |
6K5M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k5m by Molmil](/molmil-images/mine/6k5m) | The crystal structure of a serotonin N-acetyltransferase from Oryza Sativa (Rice) | 分子名称: | Serotonin N-acetyltransferase 1, chloroplastic | 著者 | Zhou, Y.Z, Liao, L.J, Liu, X.K, Guo, Y, Zhao, Y.C, Zeng, Z.X. | 登録日 | 2019-05-29 | 公開日 | 2020-06-03 | 最終更新日 | 2021-09-22 | 実験手法 | X-RAY DIFFRACTION (1.793 Å) | 主引用文献 | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
3N3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3n3k by Molmil](/molmil-images/mine/3n3k) | The catalytic domain of USP8 in complex with a USP8 specific inhibitor | 分子名称: | Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Allali-Hassani, A, Lam, R, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | 登録日 | 2010-05-20 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
|
|
7F9W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f9w by Molmil](/molmil-images/mine/7f9w) | CD25 in complex with Fab | 分子名称: | Heavy chain of Fab, Interleukin-2 receptor subunit alpha, Light chain of Fab | 著者 | Liu, C. | 登録日 | 2021-07-05 | 公開日 | 2022-01-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity. Sci Rep, 11, 2021
|
|
2QT5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qt5 by Molmil](/molmil-images/mine/2qt5) | Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide | 分子名称: | (ASN)(ASN)(LEU)(GLN)(ASP)(GLY)(THR)(GLU)(VAL), 1,2-ETHANEDIOL, ACETIC ACID, ... | 著者 | Long, J, Wei, Z, Feng, W, Zhao, Y, Zhang, M. | 登録日 | 2007-08-01 | 公開日 | 2008-06-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1. J.Mol.Biol., 375, 2008
|
|
6AKL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6akl by Molmil](/molmil-images/mine/6akl) | Crystal structure of Striatin3 in complex with SIKE1 Coiled-coil domain | 分子名称: | Striatin-3, Suppressor of IKBKE 1 | 著者 | Zhou, L, Chen, M, Zhou, Z.C. | 登録日 | 2018-09-02 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
|
|
6AKK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6akk by Molmil](/molmil-images/mine/6akk) | Crystal structure of the second Coiled-coil domain of SIKE1 | 分子名称: | GLYCEROL, Suppressor of IKBKE 1 | 著者 | Zhou, L, Chen, M, Zhou, Z.C. | 登録日 | 2018-09-02 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
|
|
7YOJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yoj by Molmil](/molmil-images/mine/7yoj) | Structure of CasPi with guide RNA and target DNA | 分子名称: | CasPi, DNA (30-MER), DNA (5'-D(P*CP*GP*GP*GP*AP*TP*GP*CP*CP*CP*AP*G)-3'), ... | 著者 | Li, C.P, Wang, J, Liu, J.J. | 登録日 | 2022-08-01 | 公開日 | 2023-02-15 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | The compact Cas pi (Cas12l) 'bracelet' provides a unique structural platform for DNA manipulation. Cell Res., 33, 2023
|
|
5BNQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bnq by Molmil](/molmil-images/mine/5bnq) | Crystal structure of hRANKL-mRANK complex | 分子名称: | CHLORIDE ION, PHOSPHATE ION, SODIUM ION, ... | 著者 | Ren, J. | 登録日 | 2015-05-26 | 公開日 | 2015-10-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis. Sci Rep, 5, 2015
|
|
5LKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lku by Molmil](/molmil-images/mine/5lku) | Crystal structure of the p300 acetyltransferase catalytic core with coenzyme A. | 分子名称: | COENZYME A, Histone acetyltransferase p300,Histone acetyltransferase p300, ZINC ION | 著者 | Kaczmarska, Z, Ortega, E, Marquez, J.A, Panne, D. | 登録日 | 2016-07-25 | 公開日 | 2016-11-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure of p300 in complex with acyl-CoA variants. Nat. Chem. Biol., 13, 2017
|
|
5LKT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lkt by Molmil](/molmil-images/mine/5lkt) | Crystal structure of the p300 acetyltransferase catalytic core with butyryl-coenzyme A. | 分子名称: | Butyryl Coenzyme A, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Kaczmarska, Z, Ortega, E, Marquez, J.A, Panne, D. | 登録日 | 2016-07-24 | 公開日 | 2016-11-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structure of p300 in complex with acyl-CoA variants. Nat. Chem. Biol., 13, 2017
|
|
5LKZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lkz by Molmil](/molmil-images/mine/5lkz) | Crystal structure of the p300 acetyltransferase catalytic core with crotonyl-coenzyme A. | 分子名称: | CROTONYL COENZYME A, GLYCEROL, Histone acetyltransferase p300,Histone acetyltransferase p300, ... | 著者 | Kaczmarska, Z, Ortega, E, Marquez, J.A, Panne, D. | 登録日 | 2016-07-25 | 公開日 | 2016-11-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of p300 in complex with acyl-CoA variants. Nat. Chem. Biol., 13, 2017
|
|
6M71
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m71 by Molmil](/molmil-images/mine/6m71) | SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase | 著者 | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | 登録日 | 2020-03-16 | 公開日 | 2020-04-01 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
|
|
6AKM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6akm by Molmil](/molmil-images/mine/6akm) | Crystal structure of SLMAP-SIKE1 complex | 分子名称: | GLYCEROL, Sarcolemmal membrane-associated protein, Suppressor of IKBKE 1 | 著者 | Ma, J, Chen, M, Zhou, Z.C. | 登録日 | 2018-09-02 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
|
|
5MGR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mgr by Molmil](/molmil-images/mine/5mgr) | Human receptor NKR-P1 in glycosylated form, extracellular domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell lectin-like receptor subfamily B member 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Skalova, T, Blaha, J, Stransky, J, Koval, T, Hasek, J, Yuguang, Z, Harlos, K, Vanek, O, Dohnalek, J. | 登録日 | 2016-11-22 | 公開日 | 2018-06-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse. Nat Commun, 13, 2022
|
|
5LKX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lkx by Molmil](/molmil-images/mine/5lkx) | Crystal structure of the p300 acetyltransferase catalytic core with propionyl-coenzyme A. | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Histone acetyltransferase p300,Histone acetyltransferase p300, ... | 著者 | Kaczmarska, Z, Ortega, E, Marquez, J.A, Panne, D. | 登録日 | 2016-07-25 | 公開日 | 2016-11-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Structure of p300 in complex with acyl-CoA variants. Nat. Chem. Biol., 13, 2017
|
|
5MGS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mgs by Molmil](/molmil-images/mine/5mgs) | Human receptor NKR-P1 in deglycosylated form, extracellular domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell lectin-like receptor subfamily B member 1 | 著者 | Skalova, T, Blaha, J, Stransky, J, Koval, T, Hasek, J, Yuguang, Z, Harlos, K, Vanek, O, Dohnalek, J. | 登録日 | 2016-11-22 | 公開日 | 2018-05-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse. Nat Commun, 13, 2022
|
|
5MGT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mgt by Molmil](/molmil-images/mine/5mgt) | Complex of human NKR-P1 and LLT1 in deglycosylated forms | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D, CHLORIDE ION, ... | 著者 | Blaha, J, Skalova, T, Stransky, J, Koval, T, Hasek, J, Yuguang, Z, Harlos, K, Vanek, O, Dohnalek, J. | 登録日 | 2016-11-22 | 公開日 | 2018-06-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse. Nat Commun, 13, 2022
|
|
5MJ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mj6 by Molmil](/molmil-images/mine/5mj6) | Ligand-induced conformational change of Insulin-regulated aminopeptidase: insights on catalytic mechanism and active site plasticity. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... | 著者 | Mpakali, A, Stratikos, E, Saridakis, E, Giastas, P. | 登録日 | 2016-11-30 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Ligand-Induced Conformational Change of Insulin-Regulated Aminopeptidase: Insights on Catalytic Mechanism and Active Site Plasticity. J. Med. Chem., 60, 2017
|
|
8AZR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8azr by Molmil](/molmil-images/mine/8azr) | KRAS in complex with precursor 1 | 分子名称: | (4~{S})-2-azanyl-4-[3-[6-[(2~{S})-2,4-dimethylpiperazin-1-yl]pyridin-2-yl]-1,2,4-oxadiazol-5-yl]-4-methyl-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | 著者 | Boettcher, J, Herdeis, L. | 登録日 | 2022-09-06 | 公開日 | 2023-06-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth. Nature, 619, 2023
|
|