2DI3
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6KKI
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6KKL
| Crystal structure of Drug:Proton Antiporter-1 (DHA1) Family SotB, in the inward conformation (H115N mutant) | 分子名称: | Sugar efflux transporter, nonyl beta-D-glucopyranoside | 著者 | Xiao, Q.J, Sun, B, Zuo, Y.X, Guo, L, He, J.H, Deng, D. | 登録日 | 2019-07-26 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.654 Å) | 主引用文献 | Visualizing the nonlinear changes of a drug-proton antiporter from inward-open to occluded state. Biochem.Biophys.Res.Commun., 534, 2021
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6KKK
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6KKJ
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1BSJ
| COBALT DEFORMYLASE INHIBITOR COMPLEX FROM E.COLI | 分子名称: | (S)-2-(PHOSPHONOXY)CAPROYL-L-LEUCYL-P-NITROANILIDE, COBALT (II) ION, PHOSPHATE ION, ... | 著者 | Hao, B, Gong, W, Rajagopalan, P.T, Hu, Y, Pei, D, Chan, M.K. | 登録日 | 1998-08-28 | 公開日 | 2000-04-15 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the design of antibiotics targeting peptide deformylase. Biochemistry, 38, 1999
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1BSK
| ZINC DEFORMYLASE INHIBITOR COMPLEX FROM E.COLI | 分子名称: | (S)-2-(PHOSPHONOXY)CAPROYL-L-LEUCYL-P-NITROANILIDE, PHOSPHATE ION, PROTEIN (PEPTIDE DEFORMYLASE), ... | 著者 | Hao, B, Gong, W, Rajagopalan, P.T, Hu, Y, Pei, D, Chan, M.K. | 登録日 | 1998-08-28 | 公開日 | 2000-04-15 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the design of antibiotics targeting peptide deformylase. Biochemistry, 38, 1999
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4DCQ
| Crystal Structure of the Fab Fragment of 3B5H10, an Antibody-Specific for Extended Polyglutamine Repeats (orthorhombic form) | 分子名称: | 1,2-ETHANEDIOL, 3B5H10 FAB Heavy Chain, 3B5H10 FAB Light Chain | 著者 | Peters-Libeu, C.A, Tran, T, Finkbeiner, S, Weisgraber, K. | 登録日 | 2012-01-18 | 公開日 | 2012-02-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure. J.Mol.Biol., 421, 2012
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6MJ2
| Human TRPM2 ion channel in a calcium- and ADPR-bound state | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily M member 2 | 著者 | Wang, L, Fu, T.M, Xia, S, Wu, H. | 登録日 | 2018-09-20 | 公開日 | 2018-12-12 | 最終更新日 | 2019-01-02 | 実験手法 | ELECTRON MICROSCOPY (6.36 Å) | 主引用文献 | Structures and gating mechanism of human TRPM2. Science, 362, 2018
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6MIX
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6MIZ
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1A2A
| AGKISTROTOXIN, A PHOSPHOLIPASE A2-TYPE PRESYNAPTIC NEUROTOXIN FROM AGKISTRODON HALYS PALLAS | 分子名称: | CHLORIDE ION, PHOSPHOLIPASE A2 | 著者 | Tang, L, Zhou, Y, Lin, Z. | 登録日 | 1997-12-25 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of agkistrodotoxin, a phospholipase A2-type presynaptic neurotoxin from agkistrodon halys pallas. J.Mol.Biol., 282, 1998
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2Y2T
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2Y2Y
| Oxidised form of E. coli CsgC | 分子名称: | ACETATE ION, CURLI PRODUCTION PROTEIN CSGC | 著者 | Taylor, J.D, Salgado, P.S, Constable, S.C, Cota, E, Mathews, S.J. | 登録日 | 2010-12-16 | 公開日 | 2011-09-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Atomic Resolution Insights Into Curli Fiber Biogenesis. Structure, 19, 2011
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7XG6
| Crystal structure of an (R)-selective omega-transaminase mutant from Aspergillus terreus with covalently bound PLP | 分子名称: | omega-transaminase | 著者 | Xiang, C, Wu, S.K, Weber, G, Liu, W.D, Wei, R, Bornscheuer, U.T. | 登録日 | 2022-04-03 | 公開日 | 2022-12-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | A growth selection system for the directed evolution of amine-forming or converting enzymes. Nat Commun, 13, 2022
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7XG5
| Crystal structure of an (R)-selective omega-transaminase mutant from Aspergillus terreus with PLP | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, omega-transaminase | 著者 | Xiang, C, Wu, S.K, Weber, G, Liu, W.D, Wei, R, Bornscheuer, U.T. | 登録日 | 2022-04-03 | 公開日 | 2022-12-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | A growth selection system for the directed evolution of amine-forming or converting enzymes. Nat Commun, 13, 2022
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7ZQS
| Cryo-EM Structure of Human Transferrin Receptor 1 bound to DNA Aptamer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (30-MER), ... | 著者 | Bansia, H, Wang, T, Gutierrez, D, des Georges, A. | 登録日 | 2022-05-02 | 公開日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Discovery of a Transferrin Receptor 1-Binding Aptamer and Its Application in Cancer Cell Depletion for Adoptive T-Cell Therapy Manufacturing. J.Am.Chem.Soc., 144, 2022
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7DTW
| Human Calcium-Sensing Receptor in the inactive close-close conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Extracellular calcium-sensing receptor | 著者 | Ling, S.L, Tian, C.L, Shi, P, Liu, S.L, Meng, X.Y, Liu, L, Sun, D.M, Shi, C.W. | 登録日 | 2021-01-06 | 公開日 | 2021-03-10 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca 2+ ions and L-tryptophan. Cell Res., 31, 2021
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7DTU
| Human Calcium-Sensing Receptor bound with L-Trp | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Extracellular calcium-sensing receptor, ... | 著者 | Ling, S.L, Tian, C.L, Shi, P, Liu, S.L, Meng, X.Y, Liu, L, Sun, D.M, Shi, C.W. | 登録日 | 2021-01-06 | 公開日 | 2021-03-10 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca 2+ ions and L-tryptophan. Cell Res., 31, 2021
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7E27
| Structure of PfFNT in complex with MMV007839 | 分子名称: | (Z)-4,4,5,5,5-pentakis(fluoranyl)-1-(4-methoxy-2-oxidanyl-phenyl)-3-oxidanyl-pent-2-en-1-one, Formate-nitrite transporter | 著者 | Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J. | 登録日 | 2021-02-04 | 公開日 | 2021-08-18 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | 主引用文献 | Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism. Plos Biol., 19, 2021
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7E26
| Structure of PfFNT in apo state | 分子名称: | Formate-nitrite transporter | 著者 | Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J. | 登録日 | 2021-02-04 | 公開日 | 2021-08-18 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | 主引用文献 | Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism. Plos Biol., 19, 2021
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7DTT
| Human Calcium-Sensing Receptor bound with calcium ions | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ling, S.L, Tian, C.L, Shi, P, Liu, S.L, Meng, X.Y, Sun, D.M, Liu, L, Shi, C.W. | 登録日 | 2021-01-06 | 公開日 | 2021-03-10 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca 2+ ions and L-tryptophan. Cell Res., 31, 2021
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7DTV
| Human Calcium-Sensing Receptor bound with L-Trp and calcium ions | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ling, S.L, Tian, C.L, Shi, P, Liu, S.L, Meng, X.Y, Liu, L, Sun, D.M, Shi, C.W. | 登録日 | 2021-01-06 | 公開日 | 2021-03-10 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca 2+ ions and L-tryptophan. Cell Res., 31, 2021
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1BJJ
| AGKISTRODOTOXIN, A PHOSPHOLIPASE A2-TYPE PRESYNAPTIC NEUROTOXIN FROM AGKISTRODON HALYS PALLAS | 分子名称: | AGKISTRODOTOXIN, CALCIUM ION | 著者 | Tang, L, Zhou, Y, Lin, Z. | 登録日 | 1998-06-25 | 公開日 | 1999-07-29 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of agkistrodotoxin in an orthorhombic crystal form with six molecules per asymmetric unit. Acta Crystallogr.,Sect.D, 55, 1999
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7EPC
| Cryo-EM structure of inactive mGlu7 homodimer | 分子名称: | Isoform 3 of Metabotropic glutamate receptor 7 | 著者 | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
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