7DTV

Human Calcium-Sensing Receptor bound with L-Trp and calcium ions

Summary for 7DTV

• Entry DOI: 10.2210/pdb7dtv/pdb
• Related: 7DTT 7DTU
• EMDB information: 30855
• Related PRD ID: PRD_900017
• Descriptor: Extracellular calcium-sensing receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: gpcr, class c, calcium sensing receptor, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 251484.07

Authors

Ling, S.L.,Tian, C.L.,Shi, P.,Liu, S.L.,Meng, X.Y.,Liu, L.,Sun, D.M.,Shi, C.W. (deposition date: 2021-01-06, release date: 2021-03-10, Last modification date: 2021-04-14)

• Primary citation: Ling, S.,Shi, P.,Liu, S.,Meng, X.,Zhou, Y.,Sun, W.,Chang, S.,Zhang, X.,Zhang, L.,Shi, C.,Sun, D.,Liu, L.,Tian, C.; Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca 2+ ions and L-tryptophan.; Cell Res., 31:383-394, 2021; PubMed: 33603117; DOI: 10.1038/s41422-021-00474-0

Experimental method

ELECTRON MICROSCOPY (3.5 Å)