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7PCK
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BU of 7pck by Molmil
CRYSTAL STRUCTURE OF WILD TYPE HUMAN PROCATHEPSIN K
分子名称: PROTEIN (PROCATHEPSIN K)
著者Sivaraman, J, Lalumiere, M, Menard, R, Cygler, M.
登録日1998-10-21
公開日1999-10-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of wild-type human procathepsin K.
Protein Sci., 8, 1999
3ZP8
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BU of 3zp8 by Molmil
HIGH-RESOLUTION FULL-LENGTH HAMMERHEAD RIBOZYME
分子名称: HAMMERHEAD RIBOZYME, ENZYME STRAND, SUBSTRATE STRAND, ...
著者Anderson, M, Schultz, E, Martick, M, Scott, W.G.
登録日2013-02-26
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Active-Site Monovalent Cations Revealed in a 1.55 A Resolution Hammerhead Ribozyme Structure
J.Mol.Biol., 425, 2013
3ZQJ
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BU of 3zqj by Molmil
Mycobacterium tuberculosis UvrA
分子名称: UVRABC SYSTEM PROTEIN A, ZINC ION
著者Rossi, F, Khanduja, J.S, Bortoluzzi, A, Houghton, J, Sander, P, Guthlein, C, Davis, E.O, Springer, B, Bottger, E.C, Relini, A, Penco, A, Muniyappa, K, Rizzi, M.
登録日2011-06-09
公開日2011-06-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The Biological and Structural Characterization of Mycobacterium Tuberculosis Uvra Provides Novel Insights Into its Mechanism of Action
Nucleic Acids Res., 39, 2011
8YJ7
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BU of 8yj7 by Molmil
Characerization of a novel format scFvXVHH single-chain Biparatopic antibody against a metal binding protein, MtsA
分子名称: Iron ABC transporter substrate-binding lipoprotein MtsA, ZINC ION, scFv13
著者Ito, S, Nagatoishi, S, Nakakido, M, Tsumoto, K.
登録日2024-03-01
公開日2024-06-19
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Protein Sci., 33, 2024
8ZNG
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BU of 8zng by Molmil
Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus in complex with NADPH and AKG in the steady stage of reaction
分子名称: 2-OXOGLUTARIC ACID, Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wakabayashi, T, Nakasako, M.
登録日2024-05-26
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action
To Be Published
8ZNB
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Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH in the steady stage of reaction
分子名称: Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wakabayashi, T, Nakasako, M.
登録日2024-05-26
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action
To Be Published
8YJ8
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BU of 8yj8 by Molmil
Characerization of a novel format scFvXVHH single-chain Biparatopic antibody against a metal binding protein, MtsA
分子名称: Iron ABC transporter substrate-binding lipoprotein MtsA, VHH43, ZINC ION
著者Ito, S, Nagatoishi, S, Nakakido, M, Tsumoto, K.
登録日2024-03-01
公開日2024-06-19
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Protein Sci., 33, 2024
8ZNC
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Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH, AKG in the steady stage of reaction
分子名称: 2-OXOGLUTARIC ACID, AMMONIUM ION, Glutamate dehydrogenase, ...
著者Wakabayashi, T, Nakasako, M.
登録日2024-05-26
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (2.41 Å)
主引用文献Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action
To Be Published
8YJ5
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BU of 8yj5 by Molmil
Characerization of a novel format scFvXVHH single-chain Biparatopic antibody against a metal binding protein, MtsA
分子名称: Iron ABC transporter substrate-binding lipoprotein MtsA, VHH43
著者Ito, S, Nagatoishi, S, Nakakido, M, Tsumoto, K.
登録日2024-03-01
公開日2024-06-19
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Protein Sci., 33, 2024
8ZND
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BU of 8znd by Molmil
Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH and a substrate in the steady stage of reaction
分子名称: Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wakabayashi, T, Nakasako, M.
登録日2024-05-26
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action
To Be Published
8YJ6
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BU of 8yj6 by Molmil
Characerization of a novel format scFvXVHH single-chain Biparatopic antibody against a metal binding protein, MtsA
分子名称: Iron ABC transporter substrate-binding lipoprotein MtsA, ZINC ION
著者Ito, S, Nagatoishi, S, Nakakido, M, Tsumoto, K.
登録日2024-03-01
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Protein Sci., 33, 2024
5UJH
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BU of 5ujh by Molmil
ov-GRN12-34
分子名称: Granulin
著者Bansal, P, Smout, M, Wilson, D, Caceres, C.C, Dastpeyman, M, Sotillo, J, Seifert, J, Brindley, P, Loukas, A, Daly, N.
登録日2017-01-18
公開日2018-01-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold.
J. Med. Chem., 60, 2017
9ERM
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BU of 9erm by Molmil
CTE type I tau filament from vacuolar tauopathy
分子名称: Microtubule-associated protein tau
著者Qi, C, Scheres, H.W.S, Goedert, M.
登録日2024-03-24
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395G.
Acta Neuropathol, 147, 2024
9ERN
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BU of 9ern by Molmil
CTE type II tau filament from vacuolar tauopathy
分子名称: Microtubule-associated protein tau
著者Qi, C, Scheres, H.W.S, Goedert, M.
登録日2024-03-24
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395G.
Acta Neuropathol, 147, 2024
9EZX
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BU of 9ezx by Molmil
Vibrio cholerae DdmD apo complex
分子名称: Helicase/UvrB N-terminal domain-containing protein
著者Loeff, L, Jinek, M.
登録日2024-04-14
公開日2024-06-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Molecular mechanism of plasmid elimination by the DdmDE defense system.
Science, 2024
9EZJ
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BU of 9ezj by Molmil
Apo human TDO in complex with a bound inhibitor (Cpd-4)
分子名称: Tryptophan 2,3-dioxygenase, alpha-methyl-L-tryptophan, ethyl (9~{R})-2-methoxy-4-oxidanylidene-9-[[(1~{S})-1-phenylethyl]-[(2-propan-2-ylphenyl)carbamoyl]amino]-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidine-3-carboxylate
著者Wicki, M, Mac Sweeney, A.
登録日2024-04-12
公開日2024-06-05
実験手法X-RAY DIFFRACTION (2.612 Å)
主引用文献Discovery and binding mode of small molecule inhibitors of the apo form of human TDO2
To Be Published
5M1U
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BU of 5m1u by Molmil
Solution structure of CsgF in DHPC micelles
分子名称: Curli production assembly/transport component CsgF
著者Spehr, J, Schubeis, T, Ahmed, M, Ritter, C.
登録日2016-10-10
公開日2017-10-11
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of the Curli adaptor protein CsgF.
FEBS Lett., 592, 2018
5M6A
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BU of 5m6a by Molmil
Crystal structure of cardiotoxic Bence-Jones light chain dimer H9
分子名称: Bence-Jones light chain, GLYCEROL, PHOSPHATE ION
著者Oberti, L, Rognoni, P, Bacarizo, J, Bolognesi, M, Ricagno, S.
登録日2016-10-24
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5M5K
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BU of 5m5k by Molmil
S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii in complex with adenosine and cordycepin
分子名称: 3'-DEOXYADENOSINE, ACETATE ION, ADENOSINE, ...
著者Manszewski, T, Mueller-Dieckamann, J, Jaskolski, M.
登録日2016-10-21
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystallographic and SAXS studies of S-adenosyl-l-homocysteine hydrolase from Bradyrhizobium elkanii.
IUCrJ, 4, 2017
5M65
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BU of 5m65 by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii in complex with adenine
分子名称: 1,2-ETHANEDIOL, ADENINE, Adenosylhomocysteinase, ...
著者Manszewski, T, Jaskolski, M.
登録日2016-10-24
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.945 Å)
主引用文献Crystallographic and SAXS studies ofS-adenosyl-l-homocysteine hydrolase fromBradyrhizobium elkanii.
IUCrJ, 4, 2017
6SQ7
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BU of 6sq7 by Molmil
Crystal structure of M. tuberculosis InhA in complex with NAD+ and 2-(4-chloro-3-nitrobenzoyl)benzoic acid
分子名称: 2-(4-chloranyl-3-nitro-phenyl)carbonylbenzoic acid, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Mendes, V, Sabbah, M, Coyne, A.G, Abell, C, Blundell, T.L.
登録日2019-09-03
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Fragment-Based Design ofMycobacterium tuberculosisInhA Inhibitors.
J.Med.Chem., 63, 2020
5M76
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Crystal structure of cardiotoxic Bence-Jones light chain dimer H10
分子名称: BROMIDE ION, light chain dimer
著者Oberti, L, Rognoni, P, Bacarizo, J, Bolognesi, M, Ricagno, S.
登録日2016-10-26
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MHN
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BU of 5mhn by Molmil
FXIIIa in complex with the inhibitor ZED2360
分子名称: CALCIUM ION, Coagulation factor XIII A chain, GLYCEROL, ...
著者Stieler, M, Heine, A, Klebe, G.
登録日2016-11-24
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献FXIIIa in complex with the inhibitor Mi0621
To Be Published
6SQB
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Crystal structure of M. tuberculosis InhA in complex with NAD+ and 3-(3-chlorophenyl)propanoic acid
分子名称: 3-(3-chlorophenyl)propanoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Enoyl-[acyl-carrier-protein] reductase [NADH], ...
著者Mendes, V, Sabbah, M, Coyne, A.G, Abell, C, Blundell, T.L.
登録日2019-09-03
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.774 Å)
主引用文献Fragment-Based Design ofMycobacterium tuberculosisInhA Inhibitors.
J.Med.Chem., 63, 2020
6SQD
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Crystal structure of M. tuberculosis InhA in complex with NAD+ and 2-pyrazol-1-ylbenzoic acid
分子名称: 2-pyrazol-1-ylbenzoic acid, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Mendes, V, Sabbah, M, Coyne, A.G, Abell, C, Blundell, T.L.
登録日2019-09-03
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Fragment-Based Design ofMycobacterium tuberculosisInhA Inhibitors.
J.Med.Chem., 63, 2020

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