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8GQA
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BU of 8gqa by Molmil
Crystal structure of lasso peptide epimerase MslH in complexed with precursor peptide analog MslAdeltaW21
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Poly-gamma-glutamate synthesis protein (Capsule biosynthesis protein), ...
著者Nakashima, Y, Morita, H.
登録日2022-08-29
公開日2023-06-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism.
Nat Commun, 14, 2023
8GQB
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BU of 8gqb by Molmil
Crystal structure of lasso peptide epimerase MslH D11A mutant
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Nakashima, Y, Morita, H.
登録日2022-08-29
公開日2023-06-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism.
Nat Commun, 14, 2023
5TR6
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BU of 5tr6 by Molmil
Discovery of TAK-659, an Orally Available Investigational Inhibitor of Spleen Tyrosine Kinase (SYK)
分子名称: 1,2-ETHANEDIOL, 6-{[(1R,2S)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one, Tyrosine-protein kinase SYK
著者Yano, J, Jennings, A, Lam, B, Hoffman, I.D.
登録日2016-10-25
公開日2016-11-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK).
Bioorg. Med. Chem. Lett., 26, 2016
1AG7
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BU of 1ag7 by Molmil
CONOTOXIN GS, NMR, 20 STRUCTURES
分子名称: CONOTOXIN GS
著者Hill, J.M, Alewood, P.F, Craik, D.J.
登録日1997-04-03
公開日1998-04-08
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry.
Structure, 5, 1997
4YRW
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BU of 4yrw by Molmil
rat xanthine oxidoreductase, C-terminal deletion protein variant
分子名称: BICARBONATE ION, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ...
著者Okamoto, K.
登録日2015-03-16
公開日2015-04-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase
Febs J., 282, 2015
5X7X
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BU of 5x7x by Molmil
The crystal structure of the nucleosome containing H3.3 at 2.18 angstrom resolution
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Arimura, Y, Taguchi, H, Kurumizaka, H.
登録日2017-02-27
公開日2017-04-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.184 Å)
主引用文献Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
Biochemistry, 56, 2017
5TT7
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BU of 5tt7 by Molmil
Discovery of TAK-659, an Orally Available Investigational Inhibitor of Spleen Tyrosine Kinase (SYK)
分子名称: 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-5-one, Tyrosine-protein kinase SYK
著者Yano, J, Jennings, A, Lam, B, Hoffman, I.D.
登録日2016-11-01
公開日2016-11-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK).
Bioorg. Med. Chem. Lett., 26, 2016
1AK2
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BU of 1ak2 by Molmil
ADENYLATE KINASE ISOENZYME-2
分子名称: ADENYLATE KINASE ISOENZYME-2, SULFATE ION
著者Schlauderer, G.J, Schulz, G.E.
登録日1995-12-29
公開日1996-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The structure of bovine mitochondrial adenylate kinase: comparison with isoenzymes in other compartments.
Protein Sci., 5, 1996
7EJ9
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BU of 7ej9 by Molmil
Alternative crystal structure of mouse Cryptochrome 2 in complex with TH301 compound
分子名称: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2
著者Miller, S.A, Hirota, T.
登録日2021-04-01
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021
1B1V
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BU of 1b1v by Molmil
NMR STRUCTURE OF PSP1, PLASMATOCYTE-SPREADING PEPTIDE FROM PSEUDOPLUSIA INCLUDENS
分子名称: PROTEIN (PLASMATOCYTE-SPREADING PEPTIDE)
著者Volkman, B.F, Clark, K.D, Anderson, M.E, Pech, L.L, Markley, J.L, Strand, M.R.
登録日1998-11-23
公開日1998-12-02
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of the insect cytokine peptide plasmatocyte-spreading peptide 1 from Pseudoplusia includens.
J.Biol.Chem., 274, 1999
7YDO
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BU of 7ydo by Molmil
Crystal structure of Atg44
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Uncharacterized protein C26A3.14c
著者Maruyama, T, Noda, N.N.
登録日2022-07-04
公開日2023-05-17
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy.
Mol.Cell, 83, 2023
7E0G
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BU of 7e0g by Molmil
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418, FAD-adduct
分子名称: GLYCEROL, IMIDAZOLE, Lysine-specific histone demethylase 1A, ...
著者Oki, H.
登録日2021-01-28
公開日2021-03-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models.
Sci Adv, 7, 2021
2P39
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BU of 2p39 by Molmil
Crystal structure of human FGF23
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 23
著者Mohammadi, M.
登録日2007-03-08
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
2P23
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BU of 2p23 by Molmil
Crystal structure of human FGF19
分子名称: Fibroblast growth factor 19
著者Mohammadi, M.
登録日2007-03-06
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
1B5N
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BU of 1b5n by Molmil
NMR STRUCTURE OF PSP1, PLASMATOCYTE-SPREADING PEPTIDE FROM PSEUDOPLUSIA INCLUDENS
分子名称: PROTEIN (PLASMATOCYTE-SPREADING PEPTIDE)
著者Volkman, B.F, Clark, K.D, Anderson, M.E, Pech, L.L, Markley, J.L, Strand, M.R.
登録日1999-01-07
公開日1999-01-13
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of the insect cytokine peptide plasmatocyte-spreading peptide 1 from Pseudoplusia includens.
J.Biol.Chem., 274, 1999
6KV0
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BU of 6kv0 by Molmil
Ferredoxin I from C. reinhardtii, high X-ray dose
分子名称: BENZAMIDINE, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ...
著者Onishi, Y, Kurisu, G, Tanaka, H.
登録日2019-09-03
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献X-ray dose-dependent structural changes of the [2Fe-2S] ferredoxin from Chlamydomonas reinhardtii.
J.Biochem., 167, 2020
7YL8
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BU of 7yl8 by Molmil
Neutron structure of Bacillus thermoproteolyticus Ferredoxin at room temperature
分子名称: Ferredoxin, IRON/SULFUR CLUSTER
著者Unno, M, Wada, K, Kobayashi, K.
登録日2022-07-25
公開日2024-02-07
実験手法NEUTRON DIFFRACTION (1.45 Å), X-RAY DIFFRACTION
主引用文献Protonation/deprotonation-driven switch for the redox stability of the low-potential [4Fe-4S] ferredoxin
To Be Published
6A1C
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BU of 6a1c by Molmil
Crystal structure of the CK2a1-go289 complex
分子名称: 1,2-ETHANEDIOL, 5-bromanyl-2-methoxy-4-[(E)-(3-methylsulfanyl-5-phenyl-1,2,4-triazol-4-yl)iminomethyl]phenol, Casein kinase II subunit alpha, ...
著者Kinoshita, T, Tsuyuguchi, M.
登録日2018-06-07
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.
Sci Adv, 5, 2019
6LK1
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BU of 6lk1 by Molmil
Ultrahigh resolution X-ray structure of Ferredoxin I from C. reinhardtii
分子名称: BENZAMIDINE, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin, ...
著者Onishi, Y, Kurisu, G, Tanaka, H.
登録日2019-12-17
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献X-ray dose-dependent structural changes of the [2Fe-2S] ferredoxin from Chlamydomonas reinhardtii.
J.Biochem., 167, 2020
6KUM
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BU of 6kum by Molmil
Ferredoxin I from C. reinhardtii, low X-ray dose
分子名称: BENZAMIDINE, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ...
著者Onishi, Y, Kurisu, G, Tanaka, H.
登録日2019-09-02
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献X-ray dose-dependent structural changes of the [2Fe-2S] ferredoxin from Chlamydomonas reinhardtii.
J.Biochem., 167, 2020
2QCQ
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BU of 2qcq by Molmil
Crystal structure of Bone Morphogenetic Protein-3 (BMP-3)
分子名称: Bone morphogenetic protein 3
著者Allendorph, G.P.
登録日2007-06-19
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors.
Biochemistry, 46, 2007
2QCW
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BU of 2qcw by Molmil
Crystal Structure of Bone Morphogenetic Protein-6 (BMP-6)
分子名称: Bone morphogenetic protein 6
著者Allendorph, G.P.
登録日2007-06-19
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors.
Biochemistry, 46, 2007
4I59
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BU of 4i59 by Molmil
Cyclohexylamine Oxidase from Brevibacterium oxydans IH-35A complexed with cyclohexanone
分子名称: CYCLOHEXANONE, Cyclohexylamine Oxidase, FLAVIN-ADENINE DINUCLEOTIDE
著者Mirza, I.A, Berghuis, A.M.
登録日2012-11-28
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Structural Analysis of a Novel Cyclohexylamine Oxidase from Brevibacterium oxydans IH-35A.
Plos One, 8, 2013
4I26
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BU of 4i26 by Molmil
2.20 Angstroms X-ray crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase from Pseudomonas fluorescens
分子名称: 1,2-ETHANEDIOL, 2-aminomuconate 6-semialdehyde dehydrogenase, SODIUM ION
著者Davis, I, Huo, L, Chen, L, Liu, A.
登録日2012-11-21
公開日2014-05-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Crystallographic and spectroscopic snapshots reveal a dehydrogenase in action.
Nat Commun, 6, 2015
4I58
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BU of 4i58 by Molmil
Cyclohexylamine Oxidase from Brevibacterium oxydans IH-35A
分子名称: Cyclohexylamine Oxidase, FLAVIN-ADENINE DINUCLEOTIDE
著者Mirza, I.A, Berghuis, A.M.
登録日2012-11-28
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Analysis of a Novel Cyclohexylamine Oxidase from Brevibacterium oxydans IH-35A.
Plos One, 8, 2013

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