8H9A
 
 | | Crystal structure of chemically modified E. coli ThrS catalytic domain 2 | | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
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3T9N
 | | Crystal structure of a membrane protein | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Small-conductance mechanosensitive channel | | 著者 | Yang, M, Zhang, X, Ge, J, Wang, J. | | 登録日 | 2011-08-03 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.456 Å) | | 主引用文献 | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance
Proc.Natl.Acad.Sci.USA, 109, 2012
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2F3V
 | | Solution structure of 1-110 fragment of staphylococcal nuclease with V66W mutation | | 分子名称: | Thermonuclease | | 著者 | Liu, D, Xie, T, Feng, Y, Shan, L, Ye, K, Wang, J. | | 登録日 | 2005-11-22 | | 公開日 | 2006-12-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease
Biophys.J., 92, 2007
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3JVG
 | | Crystal Structure of chicken CD1-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, CHLORIDE ION, ... | | 著者 | Dvir, H, Wang, J, Zajonc, D.M. | | 登録日 | 2009-09-16 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for lipid-antigen recognition in avian immunity.
J.Immunol., 184, 2010
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5TW5
 | | Structure of mouse CD1d with bound glycosphingolipid JJ112 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Zajonc, D.M, Wang, J. | | 登録日 | 2016-11-11 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Galactosylsphingamides: new alpha-GalCer analogues to probe the F'-pocket of CD1d.
Sci Rep, 7, 2017
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3MNM
 | | Crystal structure of GAE domain of GGA2p from Saccharomyces cerevisiae | | 分子名称: | ADP-ribosylation factor-binding protein GGA2, GLYCEROL, SULFATE ION | | 著者 | Fang, P, Wang, J, Li, X, Niu, L, Teng, M. | | 登録日 | 2010-04-21 | | 公開日 | 2010-09-08 | | 最終更新日 | 2014-03-05 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural basis for the specificity of the GAE domain of yGGA2 for its accessory proteins Ent3 and Ent5
Biochemistry, 49, 2010
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3U83
 | | Crystal structure of nectin-1 | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, Poliovirus receptor-related protein 1 | | 著者 | Zhang, N, Yan, J, Lu, G, Guo, Z, Fan, Z, Wang, J, Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2011-10-15 | | 公開日 | 2012-03-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion.
Nat Commun, 2, 2011
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7C8J
 | | Structural basis for cross-species recognition of COVID-19 virus spike receptor binding domain to bat ACE2 | | 分子名称: | Angiotensin-converting enzyme, SARS-CoV-2 Receptor binding domain, ZINC ION | | 著者 | Liu, K.F, Wang, J, Tan, S.G, Niu, S, Wu, L.L, Zhang, Y.F, Pan, X.Q, Meng, Y.M, Chen, Q, Wang, Q.H, Wang, H.W, Qi, J.X, Gao, G.F. | | 登録日 | 2020-06-01 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Cross-species recognition of SARS-CoV-2 to bat ACE2.
Proc.Natl.Acad.Sci.USA, 118, 2021
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2F3W
 | | solution structure of 1-110 fragment of staphylococcal nuclease in 2M TMAO | | 分子名称: | Thermonuclease | | 著者 | Liu, D, Xie, T, Feng, Y, Shan, L, Ye, K, Wang, J. | | 登録日 | 2005-11-22 | | 公開日 | 2006-12-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease
Biophys.J., 92, 2007
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2HR9
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3U82
 | | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion | | 分子名称: | Envelope glycoprotein D, Poliovirus receptor-related protein 1 | | 著者 | Zhang, N, Yan, J, Lu, G, Guo, Z, Fan, Z, Wang, J, Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2011-10-15 | | 公開日 | 2012-03-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.164 Å) | | 主引用文献 | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion.
Nat Commun, 2, 2011
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8IBX
 | | Structure of R2 with 3'UTR and DNA in unwinding state | | 分子名称: | 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ... | | 著者 | Deng, P, Tan, S, Wang, J, Liu, J.J. | | 登録日 | 2023-02-10 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
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8IBW
 | | Structure of R2 with 3'UTR and DNA in binding state | | 分子名称: | 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ... | | 著者 | Deng, P, Tan, S, Wang, J, Liu, J.J. | | 登録日 | 2023-02-10 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
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8IBZ
 | | Structure of R2 with 5'ORF and 3'UTR | | 分子名称: | 5ORF-linker-3UTR, Reverse transcriptase-like protein, ZINC ION | | 著者 | Deng, P, Tan, S, Wang, J, Liu, J.J. | | 登録日 | 2023-02-10 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
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8IBY
 | | Structure of R2 with 5'ORF | | 分子名称: | 5'ORF RNA, Reverse transcriptase-like protein, ZINC ION | | 著者 | Deng, P, Tan, S, Wang, J, Liu, J.J. | | 登録日 | 2023-02-10 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
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3P22
 | | Crystal structure of the ENE, a viral RNA stability element, in complex with A9 RNA | | 分子名称: | Core ENE hairpin from KSHV PAN RNA, oligo(A)9 RNA | | 著者 | Mitton-Fry, R.M, DeGregorio, S.J, Wang, J, Steitz, T.A, Steitz, J.A. | | 登録日 | 2010-10-01 | | 公開日 | 2010-12-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Poly(A) tail recognition by a viral RNA element through assembly of a triple helix.
Science, 330, 2010
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8FTL
 | | Crystal structure of the SARS-CoV-2 (COVID-19) main protease (Mpro) in complex with inhibitor Jun89-3-C1 | | 分子名称: | 3C-like proteinase nsp5, N-([1,1'-biphenyl]-4-yl)-2-chloro-N-[(1R)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]acetamide | | 著者 | Lewandowski, E.M, Butler, S.G, Hu, Y, Tan, H, Wang, J, Chen, Y. | | 登録日 | 2023-01-12 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Crystal structure of the SARS-CoV-2 (COVID-19) main protease (Mpro) in complex with inhibitor Jun89-3-C1
To Be Published
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3P5N
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7D8T
 | | MITF bHLHLZ complex with M-box DNA | | 分子名称: | DNA (5'-D(*TP*GP*TP*AP*AP*CP*AP*TP*GP*TP*GP*TP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*AP*CP*AP*CP*AP*TP*GP*TP*TP*AP*CP*AP*G)-3'), Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit | | 著者 | Guo, M, Fang, P, Wang, J. | | 登録日 | 2020-10-09 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | | 主引用文献 | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
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7D8R
 | | MITF HLHLZ structure | | 分子名称: | Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit | | 著者 | Guo, M, Fang, P, Wang, J. | | 登録日 | 2020-10-09 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
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7D8S
 | | MITF bHLHLZ apo structure | | 分子名称: | Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit, SULFATE ION | | 著者 | Guo, M, Fang, P, Wang, J. | | 登録日 | 2020-10-09 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
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3P49
 | | Crystal Structure of a Glycine Riboswitch from Fusobacterium nucleatum | | 分子名称: | GLYCINE, GLYCINE RIBOSWITCH, MAGNESIUM ION, ... | | 著者 | Butler, E.B, Wang, J, Xiong, Y, Strobel, S. | | 登録日 | 2010-10-06 | | 公開日 | 2011-04-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | | 主引用文献 | Structural basis of cooperative ligand binding by the glycine riboswitch.
Chem.Biol., 18, 2011
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7D0F
 | | cryo-EM structure of a pre-catalytic group II intron RNP | | 分子名称: | Group II intron-encoded protein LtrA, RNA (738-MER) | | 著者 | Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M. | | 登録日 | 2020-09-10 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing.
Nucleic Acids Res., 48, 2020
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7D0G
 | | Cryo-EM structure of a pre-catalytic group II intron | | 分子名称: | Group II intron-encoded protein LtrA, RNA (714-MER) | | 著者 | Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M. | | 登録日 | 2020-09-10 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing.
Nucleic Acids Res., 48, 2020
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3NS2
 | | High-resolution structure of pyrabactin-bound PYL2 | | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL2 | | 著者 | Hao, Q, Yin, P, Yan, C, Yuan, X, Wang, J, Yan, N. | | 登録日 | 2010-07-01 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.634 Å) | | 主引用文献 | Single amino acid alteration between Valine and Isoleucine determines the distinct pyrabactin selectivity by PYL1 and PYL2
J.Biol.Chem., 285, 2010
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