8FTL

Crystal structure of the SARS-CoV-2 (COVID-19) main protease (Mpro) in complex with inhibitor Jun89-3-C1

Summary for 8FTL

• Entry DOI: 10.2210/pdb8ftl/pdb
• Related: 8FIV 8FIW
• Descriptor: 3C-like proteinase nsp5, N-([1,1'-biphenyl]-4-yl)-2-chloro-N-[(1R)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]acetamide (3 entities in total)
• Functional Keywords: protease, sars-cov-2, mpro, inhibitor, covid-19, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68619.07

Authors

Lewandowski, E.M.,Butler, S.G.,Hu, Y.,Tan, H.,Wang, J.,Chen, Y. (deposition date: 2023-01-12, release date: 2024-01-17, Last modification date: 2024-11-13)

• Primary citation: Lewandowski, E.M.,Butler, S.G.,Hu, Y.,Tan, H.,Wang, J.,Chen, Y.; Crystal structure of the SARS-CoV-2 (COVID-19) main protease (Mpro) in complex with inhibitor Jun89-3-C1; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.08 Å)