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8HK6
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potassium channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-25
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HKF
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ion channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION
著者Jiang, D.H, Zhang, Z.T.
登録日2022-11-25
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
6GMI
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Genetic Engineering of an Artificial Metalloenzyme for Transfer Hydrogenation of a Self-Immolative Substrate in E. coli's Periplasm.
分子名称: IRIDIUM (III) ION, Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III)
著者Rebelein, J.G.
登録日2018-05-26
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Genetic Engineering of an Artificial Metalloenzyme for Transfer Hydrogenation of a Self-Immolative Substrate in Escherichia coli's Periplasm.
J. Am. Chem. Soc., 140, 2018
7AMN
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Structure of LuxR with DNA (repression)
分子名称: DNA (5'-D(P*TP*AP*TP*TP*GP*AP*TP*AP*AP*AP*AP*TP*TP*AP*TP*CP*AP*AP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*TP*GP*AP*TP*AP*AP*TP*TP*TP*TP*AP*TP*CP*AP*AP*TP*A)-3'), HTH-type transcriptional regulator LuxR
著者Liu, B, Reverter, D.
登録日2020-10-09
公開日2021-03-31
最終更新日2021-04-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression.
Nucleic Acids Res., 49, 2021
7AMT
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Structure of LuxR with DNA (activation)
分子名称: DNA (5'-D(P*AP*TP*AP*AP*TP*GP*AP*CP*AP*TP*TP*AP*CP*TP*GP*TP*AP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*TP*AP*CP*AP*GP*TP*AP*AP*TP*GP*TP*CP*AP*TP*TP*AP*T)-3'), HTH-type transcriptional regulator LuxR
著者Liu, B, Reverter, D.
登録日2020-10-09
公開日2021-03-31
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression.
Nucleic Acids Res., 49, 2021
7BFZ
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X-ray structure of human prostate-specific membrane antigen(PSMA) in complex with a inhibitor Glu-490
分子名称: (((S)-1-carboxy-5-((E)-2-cyano-3-(5-(1-(3-methoxy-3-oxopropyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophen-2-yl)acrylamido)pentyl)carbamoyl)-L-glutamic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rakhimbekova, A, Motlova, L, Barinka, C.
登録日2021-01-05
公開日2021-08-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging.
Nat Commun, 12, 2021
4U5T
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Crystal Structure of VBP Leucine Zipper with Bound Arylstibonic Acid
分子名称: (2Z)-3-{3-[dihydroxy(oxido)-lambda~5~-stibanyl]phenyl}prop-2-enoic acid, VBP leucine zipper
著者Stagno, J.R, Ji, X.
登録日2014-07-25
公開日2014-08-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献P6981, an arylstibonic acid, is a novel low nanomolar inhibitor of cAMP response element-binding protein binding to DNA.
Mol.Pharmacol., 82, 2012
6LMR
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Solution structure of cold shock domain and ssDNA complex
分子名称: DNA (5'-D(P*AP*AP*CP*AP*CP*CP*T)-3'), Y-box-binding protein 1
著者Fan, J, Yang, D.
登録日2019-12-26
公開日2020-07-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation.
Nucleic Acids Res., 48, 2020
6O3S
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NMR solution structure of Luffin P1
分子名称: Ribosome-inactivating protein luffin P1
著者Rosengren, K.J, Payne, C.
登録日2019-02-27
公開日2019-04-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献An Ancient Peptide Family Buried within Vicilin Precursors.
Acs Chem.Biol., 14, 2019
6O3Q
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NMR solution structure of vicilin-buried peptide-8 (VBP-8)
分子名称: Vicilin
著者Rosengren, K.J, Payne, C.
登録日2019-02-27
公開日2019-04-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献An Ancient Peptide Family Buried within Vicilin Precursors.
Acs Chem.Biol., 14, 2019
3K5V
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Structure of Abl kinase in complex with imatinib and GNF-2
分子名称: 3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, ...
著者Cowan-Jacob, S.W, Fendrich, G, Rummel, G, Strauss, A.
登録日2009-10-08
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature, 463, 2010
3DJ1
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crystal structure of TIP-1 wild type
分子名称: SULFATE ION, Tax1-binding protein 3
著者Shen, Y.
登録日2008-06-21
公開日2008-10-21
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1.
J.Mol.Biol., 384, 2008
3DJ3
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Crystal Structure of C-terminal Truncated TIP-1 (6-113)
分子名称: Tax1-binding protein 3
著者Shen, Y.
登録日2008-06-21
公開日2008-10-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1
J.Mol.Biol., 384, 2008
3DIW
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c-terminal beta-catenin bound TIP-1 structure
分子名称: Tax1-binding protein 3, decameric peptide form Catenin beta-1
著者Shen, Y.
登録日2008-06-21
公開日2008-10-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1
J.Mol.Biol., 384, 2008
7YFF
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BU of 7yff by Molmil
Structure of GluN1a-GluN2D NMDA receptor in complex with agonist glycine and competitive antagonist CPP.
分子名称: (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhang, J.L, Zhu, S.J, Zhang, M.
登録日2022-07-08
公開日2023-04-12
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
7YFL
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Structure of GluN1a-GluN2D NMDA receptor in complex with agonists glycine and glutamate.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Zhang, J.L, Zhu, S.J, Zhang, M.
登録日2022-07-08
公開日2023-04-12
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
7YFO
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Structure of GluN1a E698C-GluN2D NMDA receptor in cystines crosslinked state.
分子名称: Glutamate receptor ionotropic, NMDA 1, NMDA 2D
著者Zhang, J.L, Zhu, S.J, Zhang, M.
登録日2022-07-08
公開日2023-04-12
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
7YFR
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Structure of GluN1a E698C-GluN2D NMDA receptor in cystines non-crosslinked state.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Zhang, J.L, Zhu, S.J, Zhang, M.
登録日2022-07-09
公開日2023-04-12
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
7YK4
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ox40-antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 4, antibody-H, ...
著者Zhou, A.
登録日2022-07-21
公開日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis of a Novel Agonistic Anti-OX40 Antibody.
Biomolecules, 12, 2022
8GXL
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HUMAN SUGP1 433-577
分子名称: SURP and G-patch domain-containing protein 1
著者Xu, K, Tong, L.
登録日2022-09-20
公開日2022-12-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
8GXM
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HUMAN SUGP1 433-586
分子名称: SURP and G-patch domain-containing protein 1
著者Xu, K, Tong, L.
登録日2022-09-20
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
7YFM
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Structure of GluN1b-GluN2D NMDA receptor in complex with agonists glycine and glutamate.
分子名称: Glutamate receptor ionotropic, NMDA 2D, Isoform 6 of Glutamate receptor ionotropic, ...
著者Zhang, J.L, Zhu, S.J, Zhang, M.
登録日2022-07-08
公開日2023-03-29
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
4QOZ
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Crystal structure of the histone mRNA stem-loop, stem-loop binding protein (phosphorylated), and 3'hExo ternary complex
分子名称: 3'-5' exoribonuclease 1, Histone RNA hairpin-binding protein, histone mRNA stem-loop
著者Tan, D, Tong, L.
登録日2014-06-21
公開日2014-07-23
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Molecular mechanisms for the regulation of histone mRNA stem-loop-binding protein by phosphorylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
5UFK
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Structure of the effector protein SidK (lpg0968) from Legionella pneumophila
分子名称: GLYCEROL, effector protein SidK
著者Beyrakhova, K, Xu, C, Boniecki, M.T, Cygler, M.
登録日2017-01-04
公開日2017-05-10
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
5UF5
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BU of 5uf5 by Molmil
Structure of the effector protein SidK (lpg0968) from Legionella pneumophila (domain-swapped dimer)
分子名称: GLYCEROL, effector protein SidK
著者Beyrakhova, K, Xu, C, Boniecki, M.T, Cygler, M.
登録日2017-01-03
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017

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