7JZK
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7JZ1
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2I46
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![BU of 2i46 by Molmil](/molmil-images/mine/2i46) | Crystal structure of human TPP1 | 分子名称: | Adrenocortical dysplasia protein homolog | 著者 | Wang, F, Podell, E.R, Zaug, A.J, Yang, Y.T, Baciu, P, Else, T, Hammer, G.D, Cech, T.R, Lei, M. | 登録日 | 2006-08-21 | 公開日 | 2006-11-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature, 445, 2007
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3X2E
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![BU of 3x2e by Molmil](/molmil-images/mine/3x2e) | A thermophilic hydrolase | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Adenosylhomocysteinase | 著者 | Zheng, Y, Ko, T.P, Huang, C.H. | 登録日 | 2014-12-21 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structures of S-adenosylhomocysteine hydrolase from the thermophilic bacterium Thermotoga maritima. J.Struct.Biol., 190, 2015
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3X2F
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![BU of 3x2f by Molmil](/molmil-images/mine/3x2f) | A Thermophilic S-Adenosylhomocysteine Hydrolase | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Adenosylhomocysteinase, NITRATE ION, ... | 著者 | Zheng, Y, Ko, T.P, Huang, C.H. | 登録日 | 2014-12-21 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Crystal structures of S-adenosylhomocysteine hydrolase from the thermophilic bacterium Thermotoga maritima. J.Struct.Biol., 190, 2015
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3WGG
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![BU of 3wgg by Molmil](/molmil-images/mine/3wgg) | Crystal structure of RSP in complex with alpha-NAD+ | 分子名称: | Redox-sensing transcriptional repressor rex, SULFATE ION, alpha-Diphosphopyridine nucleotide | 著者 | Zheng, Y, Ko, T.-P, Guo, R.-T. | 登録日 | 2013-08-05 | 公開日 | 2014-08-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Binding mode of the oxidized alpha-anomer of NAD(+) to RSP, a Rex-family repressor Biochem.Biophys.Res.Commun., 456, 2015
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4ZMJ
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![BU of 4zmj by Molmil](/molmil-images/mine/4zmj) | Crystal Structure of Ligand-Free BG505 SOSIP.664 HIV-1 Env Trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | 著者 | Kwon, Y.D, Kwong, P.D. | 登録日 | 2015-05-04 | 公開日 | 2015-06-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nat.Struct.Mol.Biol., 22, 2015
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6A8G
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![BU of 6a8g by Molmil](/molmil-images/mine/6a8g) | The crystal structure of muPAin-1-IG in complex with muPA-SPD at pH8.5 | 分子名称: | PHOSPHATE ION, Urokinase-type plasminogen activator chain B, muPAin-1-IG | 著者 | Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z. | 登録日 | 2018-07-08 | 公開日 | 2019-02-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides. J.Med.Chem., 62, 2019
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6A8N
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![BU of 6a8n by Molmil](/molmil-images/mine/6a8n) | The crystal structure of muPAin-1-IG-2 in complex with muPA-SPD at pH8.5 | 分子名称: | CYS-PRO-ALA-TYR-SER-ARG-TYR-ILE-GLY-CYS, Urokinase-type plasminogen activator B | 著者 | Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z. | 登録日 | 2018-07-09 | 公開日 | 2019-02-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | 主引用文献 | Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides. J.Med.Chem., 62, 2019
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3FK0
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![BU of 3fk0 by Molmil](/molmil-images/mine/3fk0) | E. coli EPSP synthase (TIPS mutation) liganded with S3P | 分子名称: | 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE | 著者 | Schonbrunn, E. | 登録日 | 2008-12-15 | 公開日 | 2009-02-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli. J.Biol.Chem., 284, 2009
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5CFF
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3FJZ
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![BU of 3fjz by Molmil](/molmil-images/mine/3fjz) | E. coli EPSP synthase (T97I) liganded with S3P and glyphosate | 分子名称: | 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, N-(phosphonomethyl)glycine, ... | 著者 | Schonbrunn, E. | 登録日 | 2008-12-15 | 公開日 | 2009-02-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli. J.Biol.Chem., 284, 2009
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3FJX
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![BU of 3fjx by Molmil](/molmil-images/mine/3fjx) | E. coli EPSP synthase (T97I) liganded with S3P | 分子名称: | 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE | 著者 | Schonbrunn, E. | 登録日 | 2008-12-15 | 公開日 | 2009-02-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli. J.Biol.Chem., 284, 2009
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3FK1
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![BU of 3fk1 by Molmil](/molmil-images/mine/3fk1) | E. coli EPSP synthase (TIPS mutation) liganded with S3P and glyphosate | 分子名称: | 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, N-(phosphonomethyl)glycine, ... | 著者 | Schonbrunn, E. | 登録日 | 2008-12-15 | 公開日 | 2009-02-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli. J.Biol.Chem., 284, 2009
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5CEH
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![BU of 5ceh by Molmil](/molmil-images/mine/5ceh) | Structure of histone lysine demethylase KDM5A in complex with selective inhibitor | 分子名称: | 7-oxo-5-phenyl-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile, Lysine-specific demethylase 5A, NICKEL (II) ION, ... | 著者 | Kiefer, J.R, Vinogradova, M. | 登録日 | 2015-07-06 | 公開日 | 2016-05-18 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nat.Chem.Biol., 12, 2016
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3FQL
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![BU of 3fql by Molmil](/molmil-images/mine/3fql) | Hepatitis C virus polymerase NS5B (CON1 1-570) with HCV-796 inhibitor | 分子名称: | 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide, GLYCEROL, RNA-directed RNA polymerase | 著者 | Harris, S.F, Wong, A. | 登録日 | 2009-01-07 | 公開日 | 2009-02-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus. J.Biol.Chem., 284, 2009
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3FQK
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![BU of 3fqk by Molmil](/molmil-images/mine/3fqk) | Hepatitis C virus polymerase NS5B (BK 1-570) with HCV-796 inhibitor | 分子名称: | 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide, RNA-directed RNA polymerase | 著者 | Harris, S.F, Wong, A. | 登録日 | 2009-01-07 | 公開日 | 2009-02-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus. J.Biol.Chem., 284, 2009
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4JPW
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![BU of 4jpw by Molmil](/molmil-images/mine/4jpw) | Crystal structure of broadly and potently neutralizing antibody 12a21 in complex with hiv-1 strain 93th057 gp120 mutant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY 12A21, ... | 著者 | Acharya, P, Luongo, T, Zhou, T, Kwong, P.D. | 登録日 | 2013-03-19 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.904 Å) | 主引用文献 | Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Cell(Cambridge,Mass.), 153, 2013
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3WDZ
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![BU of 3wdz by Molmil](/molmil-images/mine/3wdz) | Crystal Structure of Keap1 in Complex with phosphorylated p62 | 分子名称: | Kelch-like ECH-associated protein 1, Peptide from Sequestosome-1 | 著者 | Fukutomi, T, Takagi, K, Mizushima, T, Tanaka, K, Komatsu, M, Yamamoto, M. | 登録日 | 2013-06-26 | 公開日 | 2013-09-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol.Cell, 51, 2013
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3WZL
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![BU of 3wzl by Molmil](/molmil-images/mine/3wzl) | ZEN lactonase | 分子名称: | Zearalenone hydrolase | 著者 | Ko, T.P, Huang, C.H, Liu, J.R, Guo, R.T. | 登録日 | 2014-10-01 | 公開日 | 2014-11-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure and substrate-binding mode of the mycoestrogen-detoxifying lactonase ZHD from Clonostachys rosea RSC ADV, 4, 2014
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3WZM
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![BU of 3wzm by Molmil](/molmil-images/mine/3wzm) | ZEN lactonase mutant complex | 分子名称: | (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, Zearalenone hydrolase | 著者 | Ko, T.P, Huang, C.H, Liu, J.R, Guo, R.T. | 登録日 | 2014-10-01 | 公開日 | 2014-11-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Crystal structure and substrate-binding mode of the mycoestrogen-detoxifying lactonase ZHD from Clonostachys rosea RSC ADV, 4, 2014
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1XKL
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![BU of 1xkl by Molmil](/molmil-images/mine/1xkl) | Crystal Structure of Salicylic Acid-binding Protein 2 (SABP2) from Nicotiana tabacum, NESG Target AR2241 | 分子名称: | 2-AMINO-4H-1,3-BENZOXATHIIN-4-OL, salicylic acid-binding protein 2 | 著者 | Forouhar, F, Chen, Y, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-09-29 | 公開日 | 2004-11-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity Proc.Natl.Acad.Sci.USA, 102, 2005
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4OM1
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![BU of 4om1 by Molmil](/molmil-images/mine/4om1) | Crystal structure of antibody VRC07-I30Q, G54W, S58N in complex with clade A/E 93TH057 HIV-1 gp120 core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... | 著者 | Kwon, Y.D, Kwong, P.D. | 登録日 | 2014-01-25 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.131 Å) | 主引用文献 | Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
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8HEC
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![BU of 8hec by Molmil](/molmil-images/mine/8hec) | SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | 登録日 | 2022-11-08 | 公開日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Mechanism of an RBM-targeted rabbit monoclonal antibody 9H1 neutralizing SARS-CoV-2. Biochem.Biophys.Res.Commun., 660, 2023
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8HED
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![BU of 8hed by Molmil](/molmil-images/mine/8hed) | Local refinement of the SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... | 著者 | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | 登録日 | 2022-11-08 | 公開日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Mechanism of an RBM-targeted rabbit monoclonal antibody 9H1 neutralizing SARS-CoV-2. Biochem.Biophys.Res.Commun., 660, 2023
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