6LG1
 
 | | Crystal structure of LpCGTa in complex with UDP | | 分子名称: | LpCGTa, URIDINE-5'-DIPHOSPHATE | | 著者 | Gao, H.M, Yun, C.H. | | 登録日 | 2019-12-04 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.047 Å) | | 主引用文献 | Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6LG0
 | | Crystal structure of SbCGTa in complex with UDP | | 分子名称: | SbCGTa, URIDINE-5'-DIPHOSPHATE | | 著者 | Gao, H.M, Yun, C.H. | | 登録日 | 2019-12-04 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | | 主引用文献 | Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6LFN
 | | Crystal structure of LpCGTb | | 分子名称: | LpCGTb, PHOSPHATE ION | | 著者 | Gao, H.M, Yun, C.H. | | 登録日 | 2019-12-03 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | | 主引用文献 | Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
8ILD
 | | The crystal structure of native dGTP:DNApre-I:Pol X substrate ternary complex | | 分子名称: | DNA (5'-D(*CP*AP*GP*GP*AP*TP*CP*CP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | | 著者 | Qin, T, Chen, Y.Q, Gan, J.H, Huang, Z. | | 登録日 | 2023-03-03 | | 公開日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
|
|
8ILH
 | | The crystal structure of dG(Se-Sp)-DNA:Pol X product binary complex | | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOSELENOPHOSPHATE, DNA (5'-D(*CP*GP*GP*AP*TP*CP*C)-3'), MAGNESIUM ION, ... | | 著者 | Qin, T, Gan, J.H, Huang, Z. | | 登録日 | 2023-03-03 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
|
|
8ILI
 | | The crystal structure of dG(Se-Rp)-DNA:Pol X product binary complex | | 分子名称: | DNA (5'-D(*CP*GP*GP*AP*TP*CP*CP*(7S8))-3'), MAGNESIUM ION, Repair DNA polymerase X, ... | | 著者 | Qin, T, Gan, J.H, Huang, Z. | | 登録日 | 2023-03-03 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
|
|
6B8O
 | | WT Ig-like V Domain with Phosphatidylserine | | 分子名称: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Sudom, A, Wang, Z. | | 登録日 | 2017-10-09 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
J. Biol. Chem., 293, 2018
|
|
6B3W
 | | Structure of Hs/AcPRC2 in complex with 5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one | | 分子名称: | 5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one, Enhancer of zeste 2 polycomb repressive complex 2 subunit,Enhancer of zeste 2 polycomb repressive complex 2 subunit, Polycomb protein EED, ... | | 著者 | Gajiwala, K.S, Brooun, A, Liu, W, Deng, Y, Stewart, A.E. | | 登録日 | 2017-09-25 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497).
J. Med. Chem., 61, 2018
|
|
7D88
 | |
7D89
 | |
6JDJ
 | | Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 | | 分子名称: | AcrIIC2, CRISPR-associated endonuclease Cas9 | | 著者 | Cheng, Z, Huang, X, Sun, W, Wang, Y. | | 登録日 | 2019-02-01 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
|
|
8BNS
 | |
6JD7
 | | Crystal structure of anti-CRISPR protein AcrIIC2 dimer | | 分子名称: | ACETATE ION, AcrIIC2, MAGNESIUM ION | | 著者 | Cheng, Z, Huang, X, Sun, W, Wang, Y.L. | | 登録日 | 2019-01-31 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
|
|
6JDX
 | | Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin | | 分子名称: | 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9 | | 著者 | Cheng, Z, Huang, X, Sun, W, Wang, Y. | | 登録日 | 2019-02-02 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
|
|
4NPY
 | | Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody | | 分子名称: | GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain | | 著者 | Julien, J.-P, Diwanji, D.C, Wilson, I.A. | | 登録日 | 2013-11-22 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | | 主引用文献 | The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.
Plos Pathog., 9, 2013
|
|
7DR7
 | | bovine 20S immunoproteasome | | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | 著者 | Xu, C, Cong, Y. | | 登録日 | 2020-12-26 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM of mammalian PA28 alpha beta-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28 alpha beta.
Nat Commun, 12, 2021
|
|
7DRW
 | |
6OT1
 | |
7DCJ
 | |
7DCT
 | |
7DCU
 | |
6OSY
 | |
7DCS
 | |
7M4T
 | | Menin bound to M-1121 | | 分子名称: | Menin, methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate, praseodymium triacetate | | 著者 | Stuckey, J. | | 登録日 | 2021-03-22 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression.
J.Med.Chem., 64, 2021
|
|
8Y6U
 | |
