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5B86
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Crystal structure of M-Sec
分子名称: Tumor necrosis factor alpha-induced protein 2
著者Yamashita, M, Sato, Y, Yamagata, A, Fukai, S.
登録日2016-06-12
公開日2016-10-12
最終更新日2020-02-26
実験手法X-RAY DIFFRACTION (3.017 Å)
主引用文献Distinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation.
Sci Rep, 6, 2016
1CRL
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BU of 1crl by Molmil
INSIGHTS INTO INTERFACIAL ACTIVATION FROM AN 'OPEN' STRUCTURE OF CANDIDA RUGOSA LIPASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LIPASE
著者Grochulski, P, Cygler, M.
登録日1993-03-02
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Insights into interfacial activation from an open structure of Candida rugosa lipase.
J.Biol.Chem., 268, 1993
8YTN
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BU of 8ytn by Molmil
Single-chain Fv antibody of E11
分子名称: GLYCEROL, Single-chain Fv antibody of E11
著者Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M.
登録日2024-03-26
公開日2024-07-03
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Affinity-matured antibody with a disulfide bond in H-CDR3 loop.
Arch.Biochem.Biophys., 758, 2024
8YTP
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BU of 8ytp by Molmil
Single-chain Fv antibody of E11 complex with NP-glycine under reducing conditions
分子名称: 2-[2-(3-nitro-4-oxidanyl-phenyl)ethanoylamino]ethanoic acid, Single-chain Fv antibody of E11
著者Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M.
登録日2024-03-26
公開日2024-07-03
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Affinity-matured antibody with a disulfide bond in H-CDR3 loop.
Arch.Biochem.Biophys., 758, 2024
8YTO
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Single-chain Fv antibody of E11 complex with NP-glycine
分子名称: 2-[2-(3-nitro-4-oxidanyl-phenyl)ethanoylamino]ethanoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
著者Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M.
登録日2024-03-26
公開日2024-07-03
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Affinity-matured antibody with a disulfide bond in H-CDR3 loop.
Arch.Biochem.Biophys., 758, 2024
7DTM
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BU of 7dtm by Molmil
Crystal structure of metallo-beta-lactamase IMP-1 in complex with citrate.
分子名称: CITRATE ANION, Metallo-beta-lactamase type 2, ZINC ION
著者Yamaguchi, Y, Kurosaki, H.
登録日2021-01-06
公開日2021-08-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Metallo-beta-Lactamase (IMP-1) and Its D120E Mutant in Complexes with Citrate and the Inhibitory Effect of the Benzyl Group in Citrate Monobenzyl Ester.
J.Med.Chem., 64, 2021
7DTN
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Crystal structure of metallo-beta-lactamase IMP-1 mutant (D120E) in complex with citrate.
分子名称: 2-(2-ETHOXYETHOXY)ETHANOL, CITRATE ANION, Metallo-beta-lactamase type 2, ...
著者Yamaguchi, Y, Kurosaki, H.
登録日2021-01-06
公開日2021-08-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structures of Metallo-beta-Lactamase (IMP-1) and Its D120E Mutant in Complexes with Citrate and the Inhibitory Effect of the Benzyl Group in Citrate Monobenzyl Ester.
J.Med.Chem., 64, 2021
5XXI
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Crystal structure of CYP2C9 in complex with multiple losartan molecules
分子名称: Cytochrome P450 2C9, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Maekawa, K, Adachi, M, Shah, M.B.
登録日2017-07-04
公開日2017-10-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9
Biochemistry, 56, 2017
5X24
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Crystal structure of CYP2C9 genetic variant I359L (*3) in complex with multiple losartan molecules
分子名称: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ...
著者Maekawa, K, Adachi, M, Shah, M.B.
登録日2017-01-30
公開日2017-10-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9
Biochemistry, 56, 2017
1GEG
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BU of 1geg by Molmil
CRYATAL STRUCTURE ANALYSIS OF MESO-2,3-BUTANEDIOL DEHYDROGENASE
分子名称: ACETOIN REDUCTASE, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ...
著者Otagiri, M, Kurisu, G, Ui, S, Kusunoki, M.
登録日2000-11-10
公開日2001-02-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of meso-2,3-butanediol dehydrogenase in a complex with NAD+ and inhibitor mercaptoethanol at 1.7 A resolution for understanding of chiral substrate recognition mechanisms.
J.Biochem., 129, 2001
5X2L
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BU of 5x2l by Molmil
Crystal Structure of Human Serine Racemase
分子名称: MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, Serine racemase
著者Obita, T, Matsumoto, K, Mori, H, Toyooka, N, Mizuguchi, M.
登録日2017-02-01
公開日2018-01-31
最終更新日2021-02-24
実験手法X-RAY DIFFRACTION (1.806 Å)
主引用文献Design, synthesis, and evaluation of novel inhibitors for wild-type human serine racemase.
Bioorg. Med. Chem. Lett., 2017
5X23
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BU of 5x23 by Molmil
Crystal structure of CYP2C9 genetic variant A477T (*30) in complex with multiple losartan molecules
分子名称: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ...
著者Maekawa, K, Adachi, M, Shah, M.B.
登録日2017-01-30
公開日2017-10-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9
Biochemistry, 56, 2017
5B2E
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N,N'-diacetylchitobiose deacetylase from Pyrococcus horikoshii complexed with its inhibitor MPG (acetate-containing condition)
分子名称: 2-deoxy-2-{[(S)-hydroxy(methyl)phosphoryl]amino}-beta-D-glucopyranose, HEXANE-1,6-DIOL, Putative uncharacterized protein PH0499, ...
著者Nakamura, T, Niiyama, M, Ida, K, Uegaki, K.
登録日2016-01-15
公開日2016-08-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Substrate recognition of N,N'-diacetylchitobiose deacetylase from Pyrococcus horikoshii
J.Struct.Biol., 195, 2016
7SWD
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BU of 7swd by Molmil
Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound
分子名称: 1C11 scFv, 1C3 heavy chain, 1C3 light chain, ...
著者Milligan, J.C, Yu, X, Saphire, E.O.
登録日2021-11-19
公開日2022-04-06
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
Cell, 185, 2022
6JQA
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BU of 6jqa by Molmil
Crystal structure of phyllogen, a phyllody inducing effector protein of phytoplasma.
分子名称: IODIDE ION, Phytoplasmal effector causing phyllody 1
著者Miyatake, H, Maejima, K.
登録日2019-03-29
公開日2019-05-15
最終更新日2019-05-29
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Crystal structure of phyllogen, a phyllody-inducing effector protein of phytoplasma.
Biochem.Biophys.Res.Commun., 513, 2019
3W5E
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BU of 3w5e by Molmil
Crystal structure of phosphodiesterase 4B in complex with compound 31e
分子名称: CALCIUM ION, N-tert-butyl-2-{4-[(5,5-dioxido-2-phenyl-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl)amino]phenyl}acetamide, ZINC ION, ...
著者Takahashi, M, Hanzawa, H.
登録日2013-01-28
公開日2013-05-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors
Bioorg.Med.Chem.Lett., 23, 2013
8IXU
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Rat Transcobalamin in Complex with Cobalamin
分子名称: CHLORIDE ION, COBALAMIN, NITRATE ION, ...
著者Bokhove, M, Kumasaka, T.
登録日2023-04-03
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The structure of the rat vitamin B 12 transporter TC and its complex with glutathionylcobalamin.
J.Biol.Chem., 300, 2024
8IXT
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Rat Transcobalamin in Complex with Glutathionylcobalamin
分子名称: CHLORIDE ION, COBALAMIN, GLUTATHIONE, ...
著者Bokhove, M, Kumasaka, T.
登録日2023-04-03
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The structure of the rat vitamin B 12 transporter TC and its complex with glutathionylcobalamin.
J.Biol.Chem., 300, 2024
7F8T
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BU of 7f8t by Molmil
Re-refinement of the 2XRY X-ray structure of archaeal class II CPD photolyase from Methanosarcina mazei
分子名称: Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Maestre-Reyna, M, Yang, C.-H, Huang, W.C, Nango, E, Gusti-Ngurah-Putu, E.-P, Franz-Badur, S, Wu, W.-J, Wu, H.-Y, Wang, P.-H, Liao, J.-H, Lee, C.-C, Huang, K.-F, Chang, Y.-K, Weng, J.-H, Sugahara, M, Owada, S, Joti, Y, Tanaka, R, Tono, K, Kiontke, S, Yamamoto, J, Iwata, S, Essen, L.-O, Bessho, Y, Tsai, M.-D.
登録日2021-07-02
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme.
Nat.Chem., 14, 2022
3WD9
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Crystal structure of phosphodiesterase 4B in complex with compound 10f
分子名称: 4-[(4-{2-[(2,2-dimethylpropyl)amino]-2-oxoethyl}phenyl)amino]-2-phenylpyrimidine-5-carboxamide, CALCIUM ION, ZINC ION, ...
著者Takahashi, M, Hanzawa, H.
登録日2013-06-11
公開日2013-10-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors
Bioorg.Med.Chem., 21, 2013
5B2F
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N,N'-diacetylchitobiose deacetylase from Pyrococcus horikoshii complexed with its inhibitor MPG (phosphate-containing condition)
分子名称: 2-deoxy-2-{[(S)-hydroxy(methyl)phosphoryl]amino}-beta-D-glucopyranose, Putative uncharacterized protein PH0499, ZINC ION
著者Nakamura, T, Niiyama, M, Ida, K, Uegaki, K.
登録日2016-01-15
公開日2016-08-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Substrate recognition of N,N'-diacetylchitobiose deacetylase from Pyrococcus horikoshii
J.Struct.Biol., 195, 2016
7WZU
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BU of 7wzu by Molmil
Crystal structure of metallo-beta-lactamase IMP-6.
分子名称: Beta-lactamase, ZINC ION
著者Yamaguchi, Y, Kurosaki, H.
登録日2022-02-19
公開日2023-01-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.954 Å)
主引用文献Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-beta-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution.
Acs Infect Dis., 9, 2023
1EL1
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BU of 1el1 by Molmil
X-RAY CRYSTAL STRUCTURE ANALYSIS OF CANINE MILK LYSOZYME (HOLO-TYPE)
分子名称: CALCIUM ION, LYSOZYME C
著者Koshiba, T, Yao, M, Tanaka, I, Nitta, K.
登録日2000-03-13
公開日2001-03-13
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Calcium Induced Conformational Changes of Canine Milk Lysozyme Revealed by Structural and Thermodynamical Evidences
To be Published
7C87
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Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) C50S/F80C/C207S/C213S mutant (ApPrx*F80C)
分子名称: CITRIC ACID, Peroxiredoxin
著者Himiyama, T, Nakamura, T.
登録日2020-05-29
公開日2020-12-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Rebuilding Ring-Type Assembly of Peroxiredoxin by Chemical Modification.
Bioconjug.Chem., 32, 2021
7C89
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Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) C50S/F80C/C207S/C213S mutant modified with 2-bromoacetophenone(Ph@ApPrx*)
分子名称: 2-bromanyl-1-phenyl-ethanone, CITRATE ANION, Peroxiredoxin
著者Himiyama, T, Nakamura, T.
登録日2020-05-29
公開日2020-12-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Rebuilding Ring-Type Assembly of Peroxiredoxin by Chemical Modification.
Bioconjug.Chem., 32, 2021

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