6C69
 
 | | Structure of glycolipid aGSA[12,6P] in complex with mouse CD1d | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Zajonc, D.M, Wang, J. | | 登録日 | 2018-01-18 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.937 Å) | | 主引用文献 | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
|
|
6C6E
 | | Structure of glycolipid aGSA[26,6P] in complex with mouse CD1d | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Zajonc, D.M, Wang, J. | | 登録日 | 2018-01-18 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
|
|
4KNB
 | | C-Met in complex with OSI ligand | | 分子名称: | 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor | | 著者 | Wang, J, Steinig, A.G, Li, A.H, Chen, X, Dong, H, Ferraro, C, Jin, M, Kadalbajoo, M, Kleinberg, A, Stolz, K.M, Tavares-Greco, P.A, Wang, T, Albertella, M.R, Peng, Y, Crew, L, Kahler, J. | | 登録日 | 2013-05-09 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
Bioorg.Med.Chem.Lett., 23, 2013
|
|
8SBB
 | | Cryo-EM structure of FtAlkB | | 分子名称: | Alkane 1-monooxygenase, DODECANE, FE (III) ION, ... | | 著者 | Zhang, J, Feng, L. | | 登録日 | 2023-04-03 | | 公開日 | 2023-04-26 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Structure and mechanism of the alkane-oxidizing enzyme AlkB.
Nat Commun, 14, 2023
|
|
2RBE
 | | The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors | | 分子名称: | (5R)-2-[(2-fluorophenyl)amino]-5-(1-methylethyl)-1,3-thiazol-4(5H)-one, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zhang, J, Jordan, S.R, Li, V. | | 登録日 | 2007-09-18 | | 公開日 | 2008-01-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
|
|
3OSY
 | |
7YKD
 | | Cryo-EM structure of the human chemerin receptor 1 complex with the C-terminal nonapeptide of chemerin | | 分子名称: | CHOLESTEROL, Chemerin-like receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Chen, G, Liao, Q, Ye, R.D, Wang, J. | | 登録日 | 2022-07-22 | | 公開日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Cryo-EM structure of the human chemerin receptor 1-Gi protein complex bound to the C-terminal nonapeptide of chemerin.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7VOH
 | |
5C13
 | |
8H24
 | | Leucine-rich alpha-2-glycoprotein 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich alpha-2-glycoprotein, SULFATE ION | | 著者 | Won, S.Y, Park, B.S, Lee, D.S, Kim, H.M, Han, A, Yang, J. | | 登録日 | 2022-10-04 | | 公開日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation.
Exp.Mol.Med., 55, 2023
|
|
5UFL
 | | Crystal structure of a CIP2A core domain | | 分子名称: | Protein CIP2A, ZINC ION | | 著者 | Wang, Z, Wang, J, Rao, Z, Xu, W. | | 登録日 | 2017-01-04 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56.
EMBO Rep., 18, 2017
|
|
8HXS
 | | Small_spotted catshark CD8alpha | | 分子名称: | T-cell surface glycoprotein CD8 alpha chain | | 著者 | Wang, J, Zou, J. | | 登録日 | 2023-01-05 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | The first crystal structure of CD8 alpha alpha from a cartilaginous fish.
Front Immunol, 14, 2023
|
|
7TN1
 | | Multistate design to stabilize viral class I fusion proteins | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 | | 著者 | Huang, J, Banerjee, A, Gonzalez, K, Mousa, J, Strauch, E. | | 登録日 | 2022-01-20 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A general computational design strategy for stabilizing viral class I fusion proteins.
Nat Commun, 15, 2024
|
|
6C1I
 | | Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907 | | 分子名称: | 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid | | 著者 | Shang, J, Fuhrmann, J, Brust, R, Kojetin, D.J. | | 登録日 | 2018-01-04 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | A structural mechanism for directing corepressor-selective inverse agonism of PPAR gamma.
Nat Commun, 9, 2018
|
|
3CH8
 | | The crystal structure of PDZ-Fibronectin fusion protein | | 分子名称: | C-terminal octapeptide from protein ARVCF, MAGNESIUM ION, fusion protein PDZ-Fibronectin,Fibronectin | | 著者 | Makabe, K, Huang, J, Koide, A, Koide, S. | | 登録日 | 2008-03-08 | | 公開日 | 2009-03-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution.
J.Mol.Biol., 392, 2009
|
|
7URI
 | | allo-tRNAUTu1A in the A site of the E. coli ribosome | | 分子名称: | Allo-tRNAUTu1A | | 著者 | Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J. | | 登録日 | 2022-04-22 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
|
|
7UR5
 | | allo-tRNAUTu1 in the A, P, and E sites of the E. coli ribosome | | 分子名称: | allo-tRNAUTu1 | | 著者 | Zhang, J, Krahn, N, Prabhakar, A, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J. | | 登録日 | 2022-04-21 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
|
|
7URM
 | | allo-tRNAUTu1A in the P site of the E. coli ribosome | | 分子名称: | allo-tRNAUTU1A | | 著者 | Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J. | | 登録日 | 2022-04-22 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
|
|
1Z7I
 | |
5ZX5
 | | 3.3 angstrom structure of mouse TRPM7 with EDTA | | 分子名称: | CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 7 | | 著者 | Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E. | | 登録日 | 2018-05-18 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5E86
 | | isolated SBD of BiP with loop34 modification | | 分子名称: | 78 kDa glucose-regulated protein | | 著者 | Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. | | 登録日 | 2015-10-13 | | 公開日 | 2015-12-30 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.681 Å) | | 主引用文献 | Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP.
Structure, 23, 2015
|
|
5E84
 | | ATP-bound state of BiP | | 分子名称: | 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. | | 登録日 | 2015-10-13 | | 公開日 | 2016-01-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP.
Structure, 23, 2015
|
|
7XRH
 | |
7K3J
 | |
7K3K
 | |
