5V7U
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5T5B
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5TH0
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5THC
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5TGO
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5T6L
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5SY8
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5TZL
| Structure of transthyretin in complex with the kinetic stabilizer 201 | 分子名称: | 4-(7-chloro-1,3-benzoxazol-2-yl)-2,6-diiodophenol, Transthyretin | 著者 | Connelly, S, Mortenson, D.E, Choi, S, Wilson, I.A, Powers, E.T, Kelly, J.W, Johnson, S.M. | 登録日 | 2016-11-21 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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5U65
| Camel Nanobody VHH-5 | 分子名称: | SULFATE ION, VHH-5 | 著者 | Stanfield, R.L, Wilson, I.A. | 登録日 | 2016-12-07 | 公開日 | 2017-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers. Sci Rep, 7, 2017
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5UFB
| Crystal Structure of Variable Lymphocyte Receptor (VLR) Tn4-22 (Apo) | 分子名称: | Tn4-22 | 著者 | Collins, B.C, Gunn, R.J, McKitrick, T.R, Cummings, R.D, Cooper, M.D, Herrin, B.R, Wilson, I.A. | 登録日 | 2017-01-04 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.844 Å) | 主引用文献 | Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates. Structure, 25, 2017
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5UFF
| Crystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 with Fucose(alpha-1-2)Lactose bound | 分子名称: | RBC36, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Collins, B.C, Gunn, R.J, McKitrick, T.R, Herrin, B.R, Cummings, R.D, Cooper, M.D, Wilson, I.A. | 登録日 | 2017-01-04 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.137 Å) | 主引用文献 | Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates. Structure, 25, 2017
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5T29
| Crystal structure of 10E8 Fab light chain mutant3, against the MPER region of the HIV-1 Env, in complex with the MPER epitope scaffold T117v2 | 分子名称: | 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, Antibody 10E8 FAB LIGHT CHAIN, ... | 著者 | Irimia, A, Wilson, I.A. | 登録日 | 2016-08-23 | 公開日 | 2017-03-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design. PLoS Pathog., 13, 2017
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5UM8
| Crystal structure of HIV-1 envelope trimer 16055 NFL TD CC (T569G) in complex with Fabs 35022 and PGT124 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 35022 heavy chain, ... | 著者 | Garces, F, Stanfield, R.L, Wilson, I.A. | 登録日 | 2017-01-26 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.935 Å) | 主引用文献 | Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity, 46, 2017
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5U7G
| Crystal Structure of the Catalytic Core of CBP | 分子名称: | CREB-binding protein, ZINC ION | 著者 | Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E. | 登録日 | 2016-12-12 | 公開日 | 2017-06-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UEI
| Crystal Structure of Variable Lymphocyte Receptor (VLR) O13 (Apo) | 分子名称: | CHLORIDE ION, GLYCEROL, O13 | 著者 | Gunn, R.J, Collins, B.C, McKitrick, T.R, Cummings, R.D, Herrin, B.R, Cooper, M.D, Wilson, I.A. | 登録日 | 2017-01-02 | 公開日 | 2017-10-18 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates. Structure, 25, 2017
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5VJK
| Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | 著者 | Zhu, X, Wilson, I.A. | 登録日 | 2017-04-19 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.593 Å) | 主引用文献 | Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog., 13, 2017
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5V7R
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5UI4
| Structure of NME1 covalently conjugated to imidazole fluorosulfate | 分子名称: | 4-[4-(3-methoxyphenyl)-1-(prop-2-yn-1-yl)-1H-imidazol-5-yl]phenyl sulfurofluoridate, Nucleoside diphosphate kinase A | 著者 | Mortenson, D.E, Brighty, G.J, Wilson, I.A, Kelly, J.W. | 登録日 | 2017-01-12 | 公開日 | 2018-01-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | "Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates. J. Am. Chem. Soc., 140, 2018
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5UXQ
| Structure of anti-HIV trimer apex antibody PGT143 | 分子名称: | PGT143 Fab Heavy Chain, PGT143 Fab Light Chain | 著者 | Kong, L, Wilson, I.A. | 登録日 | 2017-02-23 | 公開日 | 2017-04-19 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (2.415 Å) | 主引用文献 | A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic Beta-Hairpin Structure Immunity, 46, 2017
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5UY3
| Crystal structure of human Fab PGT144, a broadly reactive and potent HIV-1 neutralizing antibody | 分子名称: | Antibody PGT144 Fab heavy chain, Antibody PGT144 Fab light chain | 著者 | Julien, J.-P, Lee, J.H, Wilson, I.A. | 登録日 | 2017-02-23 | 公開日 | 2017-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure. Immunity, 46, 2017
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5UMN
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5VJM
| Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9) with LSTa | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | 著者 | Zhu, X, Wilson, I.A. | 登録日 | 2017-04-19 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.909 Å) | 主引用文献 | Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog., 13, 2017
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5VTR
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5VU4
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5W42
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