6XP5
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![BU of 6xp5 by Molmil](/molmil-images/mine/6xp5) | Head-Middle module of Mediator | 分子名称: | HEAT, Med22, Mediator of RNA polymerase II transcription subunit 1, ... | 著者 | Zhang, H.Q, Chen, D.C, Kornberg, R.D. | 登録日 | 2020-07-08 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Mediator structure and conformation change. Mol.Cell, 81, 2021
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3GMJ
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![BU of 3gmj by Molmil](/molmil-images/mine/3gmj) | Crystal structure of MAD MH2 domain | 分子名称: | Protein mothers against dpp | 著者 | Wu, J.W, Wang, C. | 登録日 | 2009-03-14 | 公開日 | 2009-12-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the MH2 domain of Drosophila Mad SCI.CHINA, SER.C: LIFE SCI., 52, 2009
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7C6P
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![BU of 7c6p by Molmil](/molmil-images/mine/7c6p) | Bromodomain-containing 4 BD2 in complex with 3',4',7,8- Tetrahydroxyflavonoid | 分子名称: | 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4 | 著者 | Li, J, Yu, K, Luo, Y, Zheng, W, Liang, W, Zhu, J. | 登録日 | 2020-05-22 | 公開日 | 2021-05-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor. J Enzyme Inhib Med Chem, 36, 2021
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7C2Z
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![BU of 7c2z by Molmil](/molmil-images/mine/7c2z) | Bromodomain-containing 4 BD1 in complex with 3',4',7,8-Tetrahydroxyflavone | 分子名称: | 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4, FORMIC ACID | 著者 | Li, J, Zhu, J. | 登録日 | 2020-05-10 | 公開日 | 2021-05-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor. J Enzyme Inhib Med Chem, 36, 2021
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8HHE
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![BU of 8hhe by Molmil](/molmil-images/mine/8hhe) | |
5HW4
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![BU of 5hw4 by Molmil](/molmil-images/mine/5hw4) | Crystal structure of Escherichia coli 16S rRNA methyltransferase RsmI in complex with AdoMet | 分子名称: | Ribosomal RNA small subunit methyltransferase I, S-ADENOSYLMETHIONINE | 著者 | Zhao, M, Zhang, H, Dong, Y, Gong, Y. | 登録日 | 2016-01-28 | 公開日 | 2016-10-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.211 Å) | 主引用文献 | Structural Insights into the Methylation of C1402 in 16S rRNA by Methyltransferase RsmI Plos One, 11, 2016
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7DHP
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8GRR
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![BU of 8grr by Molmil](/molmil-images/mine/8grr) | |
7YC2
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![BU of 7yc2 by Molmil](/molmil-images/mine/7yc2) | |
5VAG
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![BU of 5vag by Molmil](/molmil-images/mine/5vag) | Crystal structure of H7-specific antibody m826 in complex with the HA1 domain of hemagglutinin from H7N9 influenza virus | 分子名称: | 1,2-ETHANEDIOL, Heavy chain of antibody m826, Hemagglutinin, ... | 著者 | Song, H, Ying, T, Ji, X. | 登録日 | 2017-03-26 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin. Cell Host Microbe, 22, 2017
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6K8K
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![BU of 6k8k by Molmil](/molmil-images/mine/6k8k) | Crystal structure of Arabidopsis thaliana BIC2-CRY2 complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Wang, X, Ma, L, Guan, Z, Yin, P. | 登録日 | 2019-06-12 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2. Nat.Struct.Mol.Biol., 27, 2020
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6K8I
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![BU of 6k8i by Molmil](/molmil-images/mine/6k8i) | Crystal structure of Arabidopsis thaliana CRY2 | 分子名称: | Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Ma, L, Wang, X, Guan, Z, Yin, P. | 登録日 | 2019-06-12 | 公開日 | 2020-05-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | 主引用文献 | Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2. Nat.Struct.Mol.Biol., 27, 2020
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3KME
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![BU of 3kme by Molmil](/molmil-images/mine/3kme) | Crystal structure of catalytic domain of TACE with phenyl-pyrrolidinyl-tartrate inhibitor | 分子名称: | (2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-(thiophen-2-ylmethyl)butanamide, ISOPROPYL ALCOHOL, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, ... | 著者 | Orth, P. | 登録日 | 2009-11-10 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors. Bioorg.Med.Chem.Lett., 20, 2009
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2FB8
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![BU of 2fb8 by Molmil](/molmil-images/mine/2fb8) | Structure of the B-Raf kinase domain bound to SB-590885 | 分子名称: | (1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME, B-Raf proto-oncogene serine/threonine-protein kinase | 著者 | Lougheed, J.C, Lee, J, Chau, D.C, Stout, T.J. | 登録日 | 2005-12-08 | 公開日 | 2006-12-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885. Cancer Res., 66, 2006
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6E9Z
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![BU of 6e9z by Molmil](/molmil-images/mine/6e9z) | DHF119 filament | 分子名称: | DHF119 filament | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | 登録日 | 2018-08-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | De novo design of self-assembling helical protein filaments. Science, 362, 2018
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6E99
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6E9V
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![BU of 6e9v by Molmil](/molmil-images/mine/6e9v) | DHF79 filament | 分子名称: | DHF79 filament | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | 登録日 | 2018-08-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | De novo design of self-assembling helical protein filaments. Science, 362, 2018
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6E9L
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6E9T
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![BU of 6e9t by Molmil](/molmil-images/mine/6e9t) | DHF58 filament | 分子名称: | DHF58 filament | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | 登録日 | 2018-08-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | De novo design of self-assembling helical protein filaments. Science, 362, 2018
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6E9W
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6E9Y
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![BU of 6e9y by Molmil](/molmil-images/mine/6e9y) | DHF38 filament | 分子名称: | DHF38 filament | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | 登録日 | 2018-08-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | De novo design of self-assembling helical protein filaments. Science, 362, 2018
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6ED6
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![BU of 6ed6 by Molmil](/molmil-images/mine/6ed6) | |
5YMU
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7C01
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![BU of 7c01 by Molmil](/molmil-images/mine/7c01) | Molecular basis for a potent human neutralizing antibody targeting SARS-CoV-2 RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CB6 heavy chain, CB6 light chain, ... | 著者 | Shi, R, Qi, J, Wang, Q, Gao, F.G, Yan, J. | 登録日 | 2020-04-29 | 公開日 | 2020-05-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2. Nature, 584, 2020
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5YMT
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![BU of 5ymt by Molmil](/molmil-images/mine/5ymt) | |