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7E88
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BU of 7e88 by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-515 Fab
分子名称: BD-515 Fab Heavy Chain, BD-515 Fab Light Chain, Spike protein S1
著者Gao, C, Wei, Y, Xiao, J.
登録日2021-03-01
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E86
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BU of 7e86 by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-508 Fab
分子名称: BD-508 Fab Heavy Chain, BD-508 Fab Light Chain, Spike protein S1
著者Gao, C, Xiao, J.
登録日2021-03-01
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
6L5Z
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BU of 6l5z by Molmil
Crystal strucutre of AF9 YEATS domain in complex with a cyclopeptide inhibitor
分子名称: Protein AF-9, SC0-ALO-ALA-SC3-SC4-NH2
著者Li, Y, Chen, G, Li, H.
登録日2019-10-25
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Selective Targeting of AF9 YEATS Domain by Cyclopeptide Inhibitors with Preorganized Conformation.
J.Am.Chem.Soc., 142, 2020
6LJM
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BU of 6ljm by Molmil
Crystal structure of human Sirt5 in complex with the fluorogenic tetrapeptide substrate P13
分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, ACE-SER-LEU-GLY-SLL, NAD-dependent protein deacylase sirtuin-5, ...
著者Chen, Q, Yu, Y.
登録日2019-12-17
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Eur.J.Med.Chem., 192, 2020
6L4Z
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BU of 6l4z by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 6
分子名称: 4-(hydroxymethyl)benzoic acid, Genome polyprotein
著者Quek, J.P.
登録日2019-10-21
公開日2020-07-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease.
Antiviral Res., 175, 2020
6LJN
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BU of 6ljn by Molmil
Crystal structure of human Sirt5 in complex with the fluorogenic tetrapeptide substrate P15
分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, ACE-HIS-PHE-SER-SLL, NAD-dependent protein deacylase sirtuin-5, ...
著者Chen, Q, Yu, Y.
登録日2019-12-17
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Eur.J.Med.Chem., 192, 2020
6L50
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BU of 6l50 by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 16
分子名称: 2-sulfanylidene-1,3-thiazolidin-4-one, NS3 protease, Serine protease subunit NS2B
著者Quek, J.P.
登録日2019-10-21
公開日2020-07-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease.
Antiviral Res., 175, 2020
7WBQ
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BU of 7wbq by Molmil
Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant spike glycoprotein in complex with its receptor human ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Qi, J, Han, P.
登録日2021-12-17
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2.
Cell, 185, 2022
7WBP
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BU of 7wbp by Molmil
Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron variant spike glycoprotein in complex with its receptor human ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Qi, J, Han, P.
登録日2021-12-17
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2.
Cell, 185, 2022
6LJK
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BU of 6ljk by Molmil
Crystal structure of human Sirt5 in complex with an internally quenched fluorescent substrate GluIQF
分子名称: BE2-SER-ALA-ILE-LYS-SER-NIY-GLY-SET, GLUTARIC ACID, NAD-dependent protein deacylase sirtuin-5, ...
著者Chen, Q, Yu, Y.
登録日2019-12-17
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.394 Å)
主引用文献Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Eur.J.Med.Chem., 192, 2020
7WGZ
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BU of 7wgz by Molmil
SARS-CoV-2 spike glycoprotein trimer in open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhu, Y, Tai, L, Yin, G, Sun, F.
登録日2021-12-29
公開日2023-01-04
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022
7WGX
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BU of 7wgx by Molmil
SARS-CoV-2 spike glycoprotein trimer in closed state after treatment with Cathepsin L
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ...
著者Zhu, Y, Tai, L, Yin, G, Sun, F.
登録日2021-12-29
公開日2023-01-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022
7WGY
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BU of 7wgy by Molmil
SARS-CoV-2 spike glycoprotein trimer in Intermediate state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhu, Y, Tai, L, Yin, G, Sun, F.
登録日2021-12-29
公開日2023-01-04
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022
7X78
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BU of 7x78 by Molmil
L-fuculose 1-phosphate aldolase
分子名称: L-fuculose phosphate aldolase, MAGNESIUM ION, SULFATE ION
著者Lou, X, Zhang, Q, Bartlam, M.
登録日2022-03-09
公開日2022-04-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural characterization of an L-fuculose-1-phosphate aldolase from Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 607, 2022
5ZQ4
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BU of 5zq4 by Molmil
PDE-Ubi-ADPr
分子名称: ADENOSINE MONOPHOSPHATE, SidE, ubiquitin
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.217 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
7WGV
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BU of 7wgv by Molmil
SARS-CoV-2 spike glycoprotein trimer in closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ...
著者Zhu, Y, Tai, L, Yin, G, Sun, F.
登録日2021-12-29
公開日2023-01-04
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022
5ZQ3
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BU of 5zq3 by Molmil
PDE-Ubiquitin
分子名称: SidE, Ubiquitin
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.182 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5ZQ2
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BU of 5zq2 by Molmil
SidE apo form
分子名称: SidE
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5ZQ5
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BU of 5zq5 by Molmil
SidE-Ubi
分子名称: SidE, Ubiquitin
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.487 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5YX2
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BU of 5yx2 by Molmil
Crystal structure of DNMT3A-DNMT3L in complex with DNA containing two CpG sites
分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
著者Zhang, Z.M, Song, J.
登録日2017-12-01
公開日2018-01-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.653 Å)
主引用文献Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
5ZQ7
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BU of 5zq7 by Molmil
SidE-Ubi-NAD
分子名称: ADENOSINE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SidE, ...
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.847 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5ZQ6
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BU of 5zq6 by Molmil
SidE-Ubi-ADPr
分子名称: ADENOSINE-5'-DIPHOSPHATE, SidE, Ubiquitin
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.009 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
7XRF
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BU of 7xrf by Molmil
Crystal structaure of DgpB/C complex
分子名称: AP_endonuc_2 domain-containing protein, DgpB, MANGANESE (II) ION
著者Ma, M, He, P.
登録日2022-05-10
公開日2023-02-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.137 Å)
主引用文献Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C -glycoside cleaving enzyme and an O - to C -glycoside isomerase.
Acta Pharm Sin B, 13, 2023
7XRE
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BU of 7xre by Molmil
Crystal structure of DgpA
分子名称: DgpA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Ma, W, He, P.
登録日2022-05-10
公開日2023-02-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C -glycoside cleaving enzyme and an O - to C -glycoside isomerase.
Acta Pharm Sin B, 13, 2023
7XR9
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BU of 7xr9 by Molmil
Crystal structure of DgpA with glucose
分子名称: DgpA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, beta-D-glucopyranose
著者Ma, W, He, P.
登録日2022-05-09
公開日2023-04-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C -glycoside cleaving enzyme and an O - to C -glycoside isomerase.
Acta Pharm Sin B, 13, 2023

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