8WI0
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![BU of 8wi0 by Molmil](/molmil-images/mine/8wi0) | wt-hMRP5 inward-open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI5
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![BU of 8wi5 by Molmil](/molmil-images/mine/8wi5) | M5PI-bound hMRP5 | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI4
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![BU of 8wi4 by Molmil](/molmil-images/mine/8wi4) | m6-hMRP5 inward open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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7QJU
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![BU of 7qju by Molmil](/molmil-images/mine/7qju) | EED in complex with PRC2 allosteric inhibitor compound 7 | 分子名称: | CHLORIDE ION, Histone-lysine N-methyltransferase EZH2, N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-[4-[(dimethylamino)methyl]phenyl]-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H, Scheufler, C. | 登録日 | 2021-12-17 | 公開日 | 2022-04-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. J.Med.Chem., 65, 2022
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7QJG
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![BU of 7qjg by Molmil](/molmil-images/mine/7qjg) | EED in complex with PRC2 allosteric inhibitor compound 6 | 分子名称: | CHLORIDE ION, Histone-lysine N-methyltransferase EZH2, N-(2,3-dihydro-1-benzofuran-7-ylmethyl)-8-[4-[(dimethylamino)methyl]phenyl]-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H, Scheufler, C. | 登録日 | 2021-12-16 | 公開日 | 2022-04-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. J.Med.Chem., 65, 2022
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7QK4
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![BU of 7qk4 by Molmil](/molmil-images/mine/7qk4) | EED in complex with PRC2 allosteric inhibitor compound 22 (MAK683) | 分子名称: | CHLORIDE ION, Histone-lysine N-methyltransferase EZH2, N-[(5-fluoranyl-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H, Scheufler, C. | 登録日 | 2021-12-17 | 公開日 | 2022-04-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | 主引用文献 | Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. J.Med.Chem., 65, 2022
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7OQ6
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![BU of 7oq6 by Molmil](/molmil-images/mine/7oq6) | Crystal structure of cytochrome P450 Sas16 from Streptomyces asterosporus | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION | 著者 | Zhang, L, Zhang, S, Bechthold, A, Einsle, O. | 登録日 | 2021-06-02 | 公開日 | 2022-06-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate. Acta Pharm Sin B, 13, 2023
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8U8M
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![BU of 8u8m by Molmil](/molmil-images/mine/8u8m) | X-ray crystal structure of TEBP-1 MCD2 homodimer | 分子名称: | COBALT (II) ION, Double-strand telomeric DNA-binding proteins 1 | 著者 | Nandakumar, J, Padmanaban, S. | 登録日 | 2023-09-18 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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8U8L
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![BU of 8u8l by Molmil](/molmil-images/mine/8u8l) | X-ray crystal structure of TEBP-2 MCD3 with ds DNA | 分子名称: | CESIUM ION, DNA (5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*CP*A)-3'), ... | 著者 | Nandakumar, J, Padmanaban, S. | 登録日 | 2023-09-18 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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7DPF
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7DQ7
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![BU of 7dq7 by Molmil](/molmil-images/mine/7dq7) | Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 5F5 | 分子名称: | 5F5 VH, 5F5 VL, Capsid protein VP4, ... | 著者 | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | 登録日 | 2020-12-22 | 公開日 | 2021-05-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DQ4
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![BU of 7dq4 by Molmil](/molmil-images/mine/7dq4) | Cryo-EM structure of CAR triggered Coxsackievirus B1 A-particle | 分子名称: | VP2, VP3, Virion protein 1 | 著者 | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | 登録日 | 2020-12-22 | 公開日 | 2021-05-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DPG
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![BU of 7dpg by Molmil](/molmil-images/mine/7dpg) | Cryo-EM structure of Coxsackievirus B1 empty particle | 分子名称: | VP2, VP3, Virion protein 1 | 著者 | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q, Xia, N. | 登録日 | 2020-12-18 | 公開日 | 2021-05-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DPZ
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![BU of 7dpz by Molmil](/molmil-images/mine/7dpz) | Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR | 分子名称: | Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ... | 著者 | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | 登録日 | 2020-12-22 | 公開日 | 2021-05-05 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DQ1
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![BU of 7dq1 by Molmil](/molmil-images/mine/7dq1) | Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR at physiological temperature | 分子名称: | Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ... | 著者 | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | 登録日 | 2020-12-22 | 公開日 | 2021-05-05 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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8C3Y
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7DL9
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![BU of 7dl9 by Molmil](/molmil-images/mine/7dl9) | |
7DLA
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8C44
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![BU of 8c44 by Molmil](/molmil-images/mine/8c44) | HB3VAR03 apo headstructure (PfEMP1 A) complexed with EPCR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, PHOSPHATIDYLETHANOLAMINE, ... | 著者 | Raghavan, S.S.R, Lavstsen, T, Wang, K.T. | 登録日 | 2022-12-31 | 公開日 | 2023-08-16 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1. Structure, 31, 2023
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6LCY
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![BU of 6lcy by Molmil](/molmil-images/mine/6lcy) | Crystal structure of Synaptotagmin-7 C2B in complex with IP6 | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-7 | 著者 | Zhang, Y, Zhang, X, Rao, F, Wang, C. | 登録日 | 2019-11-20 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | 5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis. Nat Metab, 3, 2021
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7YMD
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![BU of 7ymd by Molmil](/molmil-images/mine/7ymd) | Cryo-EM structure of Nse1/3/4 | 分子名称: | Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, Non-structural maintenance of chromosomes element 1 | 著者 | Qian, L, Jun, Z, Zhenguo, C, Wang, L. | 登録日 | 2022-07-28 | 公開日 | 2024-01-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4.176 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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6FWB
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![BU of 6fwb by Molmil](/molmil-images/mine/6fwb) | Crystal structure of Mat2A at 1.79 Angstron resolution | 分子名称: | GLYCEROL, S-adenosylmethionine synthase isoform type-2, SODIUM ION, ... | 著者 | Zhou, A, Wei, Z, Bai, J, Wang, H. | 登録日 | 2018-03-06 | 公開日 | 2019-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes. Ebiomedicine, 39, 2019
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6LHO
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![BU of 6lho by Molmil](/molmil-images/mine/6lho) | The cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab 18A7 | 分子名称: | VP1 protein, VP2 protein, VP3 protein | 著者 | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | 登録日 | 2019-12-09 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe, 27, 2020
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8VK2
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![BU of 8vk2 by Molmil](/molmil-images/mine/8vk2) | X-ray crystal structure of human IgE 4C8 Fab | 分子名称: | IgE 4C8 heavy chain, IgE 4C8 light chain | 著者 | Khatri, K, Ball, A, Smith, S.A, Champan, M.D, Pomes, A, Chruszcz, M. | 登録日 | 2024-01-08 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.508 Å) | 主引用文献 | Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2. J.Allergy Clin.Immunol., 2024
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6L31
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![BU of 6l31 by Molmil](/molmil-images/mine/6l31) | L1 protein of human papillomavirus 6 | 分子名称: | Major capsid protein L1 | 著者 | Li, S.W, Liu, X.L, Gu, Y. | 登録日 | 2019-10-07 | 公開日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection. Emerg Microbes Infect, 8, 2019
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