5AYF
 
 | | Crystal structure of SET7/9 in complex with cyproheptadine | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(dibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-1-methyl-piperidine, Histone-lysine N-methyltransferase SETD7, ... | | 著者 | Niwa, H, Handa, N, Takemoto, Y, Ito, A, Tomabechi, Y, Umehara, T, Shirouzu, M, Yoshida, M, Yokoyama, S. | | 登録日 | 2015-08-20 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | | 主引用文献 | Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription
J.Med.Chem., 59, 2016
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1KXY
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1KXX
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6U2U
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5Y4H
 | | Human SIRT3 in complex with halistanol sulfate | | 分子名称: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial, THr-Arg-Ser-GLY-ALY-VAL-MET-ARG-ARG-LEU-ARG-ARG, ... | | 著者 | Kudo, N, Ito, A, Yoshida, M. | | 登録日 | 2017-08-03 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Halistanol sulfates I and J, new SIRT1-3 inhibitory steroid sulfates from a marine sponge of the genus Halichondria
J. Antibiot., 71, 2018
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2DYT
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7ZYU
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6LYC
 | | Crystal structure of the NOD SIRPa complex with D4-2 | | 分子名称: | ACETIC ACID, D4-2, SIRPa of the NOD mouse strain | | 著者 | Murata, Y, Matsuda, M, Nakagawa, A, Matozaki, T. | | 登録日 | 2020-02-14 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Macrocyclic Peptide-Mediated Blockade of the CD47-SIRP alpha Interaction as a Potential Cancer Immunotherapy.
Cell Chem Biol, 27, 2020
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2RSD
 | | Solution structure of the plant homeodomain (PHD) of the E3 SUMO ligase Siz1 from rice | | 分子名称: | E3 SUMO-protein ligase SIZ1, ZINC ION | | 著者 | Shindo, H, Tsuchiya, W, Suzuki, R, Yamazaki, T. | | 登録日 | 2012-01-12 | | 公開日 | 2012-08-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | PHD finger of the SUMO ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 2
Febs Lett., 586, 2012
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1KXW
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6QDR
 | | Crystal structure of 14-3-3sigma in complex with a PAK6 pT99 phosphopeptide | | 分子名称: | 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C. | | 登録日 | 2019-01-02 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.615 Å) | | 主引用文献 | Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.
Cell Chem Biol, 27, 2020
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2RJ2
 | | Crystal Structure of the Sugar Recognizing SCF Ubiquitin Ligase at 1.7 Resolution | | 分子名称: | CHLORIDE ION, F-box only protein 2, NICKEL (II) ION | | 著者 | Vaijayanthimala, S, Velmurugan, D, Mizushima, T, Yamane, T, Yoshida, Y, Tanaka, K. | | 登録日 | 2007-10-14 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of the Sugar Recognizing SCF Ubiquitin Ligase at 1.7 Resolution
To be Published
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6QHM
 | | 14-3-3 sigma with RelA/p65 binding site pS281 | | 分子名称: | 14-3-3 protein sigma, LEU-SEP-GLU | | 著者 | Wolter, M, Ottmann, C. | | 登録日 | 2019-01-16 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products.
J.Am.Chem.Soc., 142, 2020
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5TEF
 | | Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, GLYCEROL, Gem-associated protein 5, ... | | 著者 | Chao, X, Tempel, W, Bian, C, He, H, Cerovina, T, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2016-09-21 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Genes Dev., 30, 2016
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5TEE
 | | Crystal structure of Gemin5 WD40 repeats in apo form | | 分子名称: | GLYCEROL, Gem-associated protein 5, SODIUM ION, ... | | 著者 | Chao, X, Tempel, W, Bian, C, Cerovina, T, He, H, Walker, J.R, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2016-09-21 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Genes Dev., 30, 2016
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5Y0R
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7OBG
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7OBS
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5Y0N
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7OB8
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7OBD
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7OBT
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7OBK
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7OBH
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7OB5
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