1LYV
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![BU of 1lyv by Molmil](/molmil-images/mine/1lyv) | High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase C403A mutant in complex with phosphate. | 分子名称: | CHLORIDE ION, PHOSPHATE ION, PROTEIN-TYROSINE PHOSPHATASE YOPH | 著者 | Evdokimov, A.G, Waugh, D.S, Routzahn, K, Tropea, J, Cherry, S. | 登録日 | 2002-06-08 | 公開日 | 2002-07-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.363 Å) | 主引用文献 | High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase C403A mutant in complex with phosphate. To be Published
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5VFI
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![BU of 5vfi by Molmil](/molmil-images/mine/5vfi) | Bruton's tyrosine kinase (BTK) with GDC-0853 | 分子名称: | 1,2-ETHANEDIOL, 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, SULFATE ION, ... | 著者 | Steinbacher, S, Eigenbrot, C. | 登録日 | 2017-04-07 | 公開日 | 2018-02-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development. J. Med. Chem., 61, 2018
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3UN0
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![BU of 3un0 by Molmil](/molmil-images/mine/3un0) | Crystal Structure of MDC1 FHA Domain | 分子名称: | Mediator of DNA damage checkpoint protein 1, SULFATE ION | 著者 | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | 登録日 | 2011-11-15 | 公開日 | 2011-12-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
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3UOT
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![BU of 3uot by Molmil](/molmil-images/mine/3uot) | Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus | 分子名称: | Mediator of DNA damage checkpoint protein 1 | 著者 | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | 登録日 | 2011-11-17 | 公開日 | 2011-12-28 | 最終更新日 | 2012-07-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
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4UMN
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![BU of 4umn by Molmil](/molmil-images/mine/4umn) | Structure of a stapled peptide antagonist bound to Nutlin-resistant Mdm2. | 分子名称: | E3 ubiquitin-protein ligase Mdm2, M06 | 著者 | Chee, S, Wongsantichon, J, Quah, S, Robinson, R.C, Verma, C, Lane, D.P, Brown, C.J, Ghadessy, F.J. | 登録日 | 2014-05-20 | 公開日 | 2014-05-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2. PLoS ONE, 9, 2014
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7LFV
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![BU of 7lfv by Molmil](/molmil-images/mine/7lfv) | |
7LFU
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![BU of 7lfu by Molmil](/molmil-images/mine/7lfu) | |
4FR2
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![BU of 4fr2 by Molmil](/molmil-images/mine/4fr2) | Alcohol dehydrogenase from Oenococcus oeni | 分子名称: | 1,3-propanediol dehydrogenase, NICKEL (II) ION | 著者 | Fodor, K, Skander, E, Wilmanns, M. | 登録日 | 2012-06-26 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and biochemical characterisation of a NAD(+)-dependent alcohol dehydrogenase from Oenococcus oeni as a new model molecule for industrial biotechnology applications. Appl.Microbiol.Biotechnol., 97, 2013
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7MWI
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![BU of 7mwi by Molmil](/molmil-images/mine/7mwi) | Crystal structure of human BAZ2A | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2A, UNKNOWN ATOM OR ION | 著者 | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2021-05-17 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status. J.Biol.Chem., 297, 2021
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5CZJ
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8K8A
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![BU of 8k8a by Molmil](/molmil-images/mine/8k8a) | |
8K89
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![BU of 8k89 by Molmil](/molmil-images/mine/8k89) | Crystal structure of NFIL3 | 分子名称: | Nuclear factor interleukin-3-regulated protein | 著者 | Min, J.R, Chen, S.Z, Liu, K. | 登録日 | 2023-07-29 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for specific DNA sequence recognition by the transcription factor NFIL3. J.Biol.Chem., 300, 2024
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8K8D
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8K86
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![BU of 8k86 by Molmil](/molmil-images/mine/8k86) | Crystal structure of NFIL3 in complex with TTATGTAA DNA | 分子名称: | DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*TP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*AP*CP*AP*TP*AP*AP*TP*G)-3'), Nuclear factor interleukin-3-regulated protein | 著者 | Min, J.R, Chen, S.Z, Liu, K. | 登録日 | 2023-07-28 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Structural basis for specific DNA sequence recognition by the transcription factor NFIL3. J.Biol.Chem., 300, 2024
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8K8C
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![BU of 8k8c by Molmil](/molmil-images/mine/8k8c) | Crystal structure of C/EBPalpha BZIP domain bound to a high affinity DNA | 分子名称: | CCAAT/enhancer-binding protein alpha, DNA (5'-D(*CP*AP*TP*TP*AP*CP*GP*TP*AP*AP*TP*GP*A)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*CP*GP*TP*AP*AP*TP*GP*T)-3'), ... | 著者 | Min, J.R, Chen, S.Z, Liu, K. | 登録日 | 2023-07-29 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Structural basis for specific DNA sequence recognition by the transcription factor NFIL3. J.Biol.Chem., 300, 2024
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6XDF
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![BU of 6xdf by Molmil](/molmil-images/mine/6xdf) | Crystal structure of IRE1a in complex with G-4100 | 分子名称: | 4-amino-N-(6-chloro-2-fluoro-3-{[(pyrrolidin-1-yl)sulfonyl]amino}phenyl)quinazoline-8-carboxamide, SODIUM ION, Serine/threonine-protein kinase/endoribonuclease IRE1 | 著者 | Steinbacher, S, Wang, W. | 登録日 | 2020-06-10 | 公開日 | 2021-04-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1 alpha Inhibitory Activity. Acs Med.Chem.Lett., 11, 2020
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6BOZ
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![BU of 6boz by Molmil](/molmil-images/mine/6boz) | Structure of human SETD8 in complex with covalent inhibitor MS4138 | 分子名称: | 1,2-ETHANEDIOL, N-(3-{[7-(2-aminoethoxy)-6-methoxy-2-(pyrrolidin-1-yl)quinazolin-4-yl]amino}propyl)prop-2-enamide, N-lysine methyltransferase KMT5A | 著者 | Babault, N, Anqi, M, Jin, J. | 登録日 | 2017-11-21 | 公開日 | 2019-05-01 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The dynamic conformational landscape of the protein methyltransferase SETD8. Elife, 8, 2019
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1AO0
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6ZUE
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![BU of 6zue by Molmil](/molmil-images/mine/6zue) | |
6PI7
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5HZB
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![BU of 5hzb by Molmil](/molmil-images/mine/5hzb) | Crystal structure of GII.10 P domain in complex with 2-fucosyllactose (2'FL) | 分子名称: | 1,2-ETHANEDIOL, Capsid protein, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Hansman, G.S, Koromyslova, A.D, Singh, B.K.S. | 登録日 | 2016-02-02 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.553 Å) | 主引用文献 | Structural Basis for Norovirus Inhibition by Human Milk Oligosaccharides. J.Virol., 90, 2016
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5HZA
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![BU of 5hza by Molmil](/molmil-images/mine/5hza) | Crystal structure of GII.10 P domain in complex with 3-fucosyllactose (3 FL) | 分子名称: | 1,2-ETHANEDIOL, Capsid protein, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]beta-D-glucopyranose | 著者 | Hansman, G.S, Koromyslova, A.D, Singh, B.K. | 登録日 | 2016-02-02 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural Basis for Norovirus Inhibition by Human Milk Oligosaccharides. J.Virol., 90, 2016
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4REO
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![BU of 4reo by Molmil](/molmil-images/mine/4reo) | Mutant ribosomal protein l1 from thermus thermophilus with threonine 217 replaced by valine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 50S ribosomal protein L1, GLYCINE, ... | 著者 | Gabdulkhakov, A.G, Nevskaya, N.A, Tishchenko, S.V, Nikonov, S.V. | 登録日 | 2014-09-23 | 公開日 | 2015-03-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions. Acta Crystallogr.,Sect.D, 71, 2015
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4IS6
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![BU of 4is6 by Molmil](/molmil-images/mine/4is6) | Crystal structure of HLA-DR4 bound to GP100 peptide | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ... | 著者 | Li, Y. | 登録日 | 2013-01-16 | 公開日 | 2013-10-23 | 最終更新日 | 2013-11-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-Based Design of Altered MHC Class II-Restricted Peptide Ligands with Heterogeneous Immunogenicity. J.Immunol., 191, 2013
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4QGB
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![BU of 4qgb by Molmil](/molmil-images/mine/4qgb) | Crystal structure of mutant ribosomal protein G219V TthL1 | 分子名称: | 50S ribosomal protein L1, ACETATE ION, CHLORIDE ION | 著者 | Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V. | 登録日 | 2014-05-22 | 公開日 | 2015-02-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions. Acta Crystallogr.,Sect.D, 71, 2015
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