1NCR
 
 | | The structure of Rhinovirus 16 when complexed with pleconaril, an antiviral compound | | 分子名称: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, MYRISTIC ACID, ZINC ION, ... | | 著者 | Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. | | 登録日 | 2002-12-05 | | 公開日 | 2003-12-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
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1NJS
 | | human GAR Tfase in complex with hydrolyzed form of 10-trifluoroacetyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid | | 分子名称: | N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID, PHOSPHATE ION, Phosphoribosylglycinamide formyltransferase | | 著者 | Zhang, Y, Desharnais, J, Marsilje, T.H, Li, C, Hedrick, M.P, Gooljarsingh, L.T, Tavassoli, A, Benkovic, S.J, Olson, A.J, Boger, D.L, Wilson, I.A. | | 登録日 | 2003-01-02 | | 公開日 | 2003-06-10 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Rational Design, Synthesis, Evaluation, and Crystal Structure of a Potent Inhibitor of Human GAR Tfase: 10-(Trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic Acid
Biochemistry, 42, 2003
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1ND3
 | | The structure of HRV16, when complexed with pleconaril, an antiviral compound | | 分子名称: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, ZINC ION, coat protein VP1, ... | | 著者 | Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. | | 登録日 | 2002-12-06 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
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1ND2
 | | The structure of Rhinovirus 16 | | 分子名称: | MYRISTIC ACID, ZINC ION, coat protein VP1, ... | | 著者 | Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. | | 登録日 | 2002-12-06 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
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1NCQ
 | | The structure of HRV14 when complexed with pleconaril, an antiviral compound | | 分子名称: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, COAT PROTEIN VP1, COAT PROTEIN VP2, ... | | 著者 | Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. | | 登録日 | 2002-12-05 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
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1FKC
 | | HUMAN PRION PROTEIN (MUTANT E200K) FRAGMENT 90-231 | | 分子名称: | PRION PROTEIN | | 著者 | Zhang, Y, Swietnicki, W, Zagorski, M.G, Surewicz, W.K, Soennichsen, F.D. | | 登録日 | 2000-08-09 | | 公開日 | 2000-09-21 | | 最終更新日 | 2018-03-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases.
J.Biol.Chem., 275, 2000
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1FO7
 | | HUMAN PRION PROTEIN MUTANT E200K FRAGMENT 90-231 | | 分子名称: | PRION PROTEIN | | 著者 | Zhang, Y, Swietnicki, W, Zagorski, M.G, Surewicz, W.K, Soennichsen, F.D. | | 登録日 | 2000-08-25 | | 公開日 | 2000-09-21 | | 最終更新日 | 2018-03-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases.
J.Biol.Chem., 275, 2000
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1FNL
 | | CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF A HUMAN FCGRIII | | 分子名称: | LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR III-B, MERCURY (II) ION | | 著者 | Zhang, Y, Boesen, C.C, Radaev, S, Brooks, A.G, Fridman, W.H, Sautes-Fridman, C, Sun, P.D. | | 登録日 | 2000-08-22 | | 公開日 | 2000-11-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the extracellular domain of a human Fc gamma RIII.
Immunity, 13, 2000
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6L2G
 | | Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase | | 分子名称: | Acetyl-CoA-acetyltransferase, putative | | 著者 | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | | 登録日 | 2019-10-03 | | 公開日 | 2020-02-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target.
Appl.Environ.Microbiol., 86, 2020
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6L2C
 | | Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase in complex with CoA | | 分子名称: | Acetyl-CoA-acetyltransferase, putative, COENZYME A | | 著者 | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | | 登録日 | 2019-10-03 | | 公開日 | 2020-02-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target.
Appl.Environ.Microbiol., 86, 2020
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6LN5
 | | CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class1) | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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1VZT
 | | ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | | 著者 | Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, X, Acharya, K.R, Brew, K. | | 登録日 | 2004-05-26 | | 公開日 | 2005-05-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity.
Biochemistry, 42, 2003
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2GHQ
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2GHT
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3OGG
 | | Crystal structure of the receptor binding domain of botulinum neurotoxin D | | 分子名称: | Botulinum neurotoxin type D | | 著者 | Zhang, Y, Gao, X, Qin, L, Buchko, G.W, Robinson, H, Varnum, S.M. | | 登録日 | 2010-08-16 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D.
Biochem.Biophys.Res.Commun., 401, 2010
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4Z69
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1MEJ
 | | Human Glycinamide Ribonucleotide Transformylase domain at pH 8.5 | | 分子名称: | GLYCEROL, PHOSPHATE ION, Phosphoribosylglycinamide formyltransferase | | 著者 | Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A. | | 登録日 | 2002-08-08 | | 公開日 | 2002-12-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR
Biochemistry, 41, 2002
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1MEO
 | | human glycinamide ribonucleotide Transformylase at pH 4.2 | | 分子名称: | PHOSPHATE ION, Phosphoribosylglycinamide formyltransferase, SULFATE ION | | 著者 | Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A. | | 登録日 | 2002-08-08 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR
Biochemistry, 41, 2002
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1MEN
 | | complex structure of human GAR Tfase and substrate beta-GAR | | 分子名称: | GLYCINAMIDE RIBONUCLEOTIDE, Phosphoribosylglycinamide formyltransferase | | 著者 | Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A. | | 登録日 | 2002-08-08 | | 公開日 | 2002-12-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR
Biochemistry, 41, 2002
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3PDU
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3PEF
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7K65
 | | Hedgehog receptor Patched (PTCH1) in complex with conformation selective nanobody TI23 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Zhang, Y, Bulkley, D.P, Liang, J, Manglik, A, Cheng, Y, Beachy, P.A. | | 登録日 | 2020-09-18 | | 公開日 | 2021-03-17 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7D6E
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7D6D
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8YM1
 | | Structure of SADS-CoV Virus Nucleocapsid Protein | | 分子名称: | nucleocapsid phosphoprotein | | 著者 | Zhang, Y, Wu, F, Xu, W. | | 登録日 | 2024-03-08 | | 公開日 | 2024-07-24 | | 最終更新日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Unraveling the assembly mechanism of SADS-CoV virus nucleocapsid protein: insights from RNA binding, dimerization, and epitope diversity profiling.
J.Virol., 98, 2024
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