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2BE1
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BU of 2be1 by Molmil
Structure of the compact lumenal domain of yeast Ire1
分子名称: Serine/threonine-protein kinase/endoribonuclease IRE1, peptide
著者Credle, J.J, Finer-Moore, J.S, Papa, F.R, Stroud, R.M, Walter, P.
登録日2005-10-21
公開日2005-12-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.983 Å)
主引用文献Inaugural Article: On the mechanism of sensing unfolded protein in the endoplasmic reticulum
Proc.Natl.Acad.Sci.Usa, 102, 2005
1FFH
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BU of 1ffh by Molmil
N AND GTPASE DOMAINS OF THE SIGNAL SEQUENCE RECOGNITION PROTEIN FFH FROM THERMUS AQUATICUS
分子名称: FFH, MAGNESIUM ION
著者Freymann, D.M, Keenan, R.J, Stroud, R.M, Walter, P.
登録日1996-12-30
公開日1997-12-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the conserved GTPase domain of the signal recognition particle.
Nature, 385, 1997
1Z9O
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BU of 1z9o by Molmil
1.9 Angstrom Crystal Structure of the Rat VAP-A MSP Homology Domain in Complex with the Rat ORP1 FFAT Motif
分子名称: Oxysterol binding protein, Vesicle-associated membrane protein-associated protein A
著者Kaiser, S.E, Brickner, J.H, Reilein, A.R, Fenn, T.D, Walter, P, Brunger, A.T.
登録日2005-04-03
公開日2005-07-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of FFAT motif-mediated ER targeting
Structure, 13, 2005
1RJ9
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BU of 1rj9 by Molmil
Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Signal Recognition Protein, ...
著者Egea, P.F, Shan, S.O, Napetschnig, J, Savage, D.F, Walter, P, Stroud, R.M.
登録日2003-11-18
公開日2004-01-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Substrate twinning activates the signal recognition particle and its receptor
Nature, 427, 2004
1Z9L
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BU of 1z9l by Molmil
1.7 Angstrom Crystal Structure of the Rat VAP-A MSP Homology Domain
分子名称: Vesicle-associated membrane protein-associated protein A
著者Kaiser, S.E, Brickner, J.H, Reilein, A.R, Fenn, T.D, Walter, P, Brunger, A.T.
登録日2005-04-03
公開日2005-07-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of FFAT motif-mediated ER targeting
Structure, 13, 2005
6URC
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BU of 6urc by Molmil
Crystal structure of IRE1a in complex with compound 18
分子名称: 2-chloro-N-(6-methyl-5-{[3-(2-{[(3S)-piperidin-3-yl]amino}pyrimidin-4-yl)pyridin-2-yl]oxy}naphthalen-1-yl)benzene-1-sulfonamide, GLYCEROL, Serine/threonine-protein kinase/endoribonuclease IRE1
著者Wallweber, H.H, Wang, W.
登録日2019-10-23
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Disruption of IRE1 alpha through its kinase domain attenuates multiple myeloma.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3KL4
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BU of 3kl4 by Molmil
Recognition of a signal peptide by the signal recognition particle
分子名称: Signal peptide of yeast dipeptidyl aminopeptidase B, Signal recognition 54 kDa protein
著者Janda, C.Y, Nagai, K, Li, J, Oubridge, C.
登録日2009-11-06
公開日2010-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Recognition of a signal peptide by the signal recognition particle.
Nature, 465, 2010
2Q9C
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BU of 2q9c by Molmil
Structure of FTSY:GMPPNP with MGCL Complex
分子名称: Cell division protein ftsY, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SULFATE ION
著者Reyes, C.L, Stroud, R.M.
登録日2007-06-12
公開日2007-07-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates.
Plos One, 2, 2007
2Q9B
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BU of 2q9b by Molmil
Structure of FTSY:GMPPNP Complex
分子名称: 1,2-ETHANEDIOL, Cell division protein ftsY, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Reyes, C.L, Stroud, R.M.
登録日2007-06-12
公開日2007-07-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates.
Plos One, 2, 2007
2Q9A
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BU of 2q9a by Molmil
Structure of Apo FTSY
分子名称: 1,2-ETHANEDIOL, Cell division protein ftsY, SULFATE ION
著者Reyes, C.L, Stroud, R.M.
登録日2007-06-12
公開日2007-07-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates.
Plos One, 2, 2007
8TQO
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BU of 8tqo by Molmil
Eukaryotic translation initiation factor 2B tetramer
分子名称: Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit epsilon, ...
著者Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P.
登録日2023-08-08
公開日2023-12-06
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling.
Nat.Chem.Biol., 20, 2024
8TQZ
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BU of 8tqz by Molmil
Eukaryotic translation initiation factor 2B with a mutation (L516A) in the delta subunit
分子名称: Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ...
著者Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P.
登録日2023-08-08
公開日2023-12-06
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling.
Nat.Chem.Biol., 20, 2024
1LS1
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BU of 1ls1 by Molmil
T. aquaticus Ffh NG Domain at 1.1A Resolution
分子名称: MAGNESIUM ION, OXYGEN MOLECULE, SIGNAL RECOGNITION PARTICLE PROTEIN
著者Ramirez, U.D, Minasov, G, Freymann, D.M.
登録日2002-05-16
公開日2002-11-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structural Basis for Mobility in the 1.1 A Crystal Structure of the NG Domain of Thermus aquaticus Ffh
J.Mol.Biol., 320, 2002
6O85
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BU of 6o85 by Molmil
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens
分子名称: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ...
著者Nguyen, H.C, Kenner, L.R, Frost, A.S.
登録日2019-03-08
公開日2019-05-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
6O81
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BU of 6o81 by Molmil
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to translation initiation factor 2 from Homo sapiens
分子名称: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ...
著者Nguyen, H, Kenner, L, Frost, A.
登録日2019-03-08
公開日2019-05-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
6O9Z
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BU of 6o9z by Molmil
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens
分子名称: Eukaryotic translation initiation factor 2 subunit 1, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ...
著者Nguyen, H.C, Kenner, L.R, Frost, A.S.
登録日2019-03-15
公開日2019-05-15
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
3FAR
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BU of 3far by Molmil
Cation-dependent self-cleavage activity in the duplex form of the subtype-B HIV-1 RNA Dimerization Initiation Site
分子名称: COBALT (II) ION, POTASSIUM ION, RNA (5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*AP*GP*CP*GP*CP*GP*CP*AP*CP*GP*GP*CP*AP*AP*G)-3')
著者Ennifar, E, Dumas, P.
登録日2008-11-18
公開日2009-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cation-dependent self-cleavage activity in the duplex form of the subtype-B HIV-1 RNA Dimerization Initiation Site
To be Published
2FCZ
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BU of 2fcz by Molmil
HIV-1 DIS kissing-loop in complex with ribostamycin
分子名称: HIV-1 DIS RNA, POTASSIUM ION, RIBOSTAMYCIN
著者Ennifar, E, Paillart, J.C, Marquet, R, Dumas, P.
登録日2005-12-13
公開日2006-05-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell.
Nucleic Acids Res., 34, 2006
2FCY
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BU of 2fcy by Molmil
HIV-1 DIS kissing-loop in complex with Neomycin
分子名称: CHLORIDE ION, HIV-1 DIS RNA, NEOMYCIN, ...
著者Ennifar, E, Paillart, J.C, Marquet, R, Dumas, P.
登録日2005-12-13
公開日2006-05-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell.
Nucleic Acids Res., 34, 2006
1CQL
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BU of 1cql by Molmil
NMR STRUCTURE OF SRP RNA DOMAIN IV
分子名称: SRP DOMAIN IV RNA
著者Schmitz, U, James, T.L.
登録日1999-08-06
公開日2000-01-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the phylogenetically most conserved domain of SRP RNA.
RNA, 5, 1999
2FD0
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BU of 2fd0 by Molmil
HIV-1 DIS kissing-loop in complex with lividomycin
分子名称: (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R ,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMET HYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL, CHLORIDE ION, HIV-1 DIS RNA, ...
著者Ennifar, E, Paillart, J.C, Marquet, R, Dumas, P.
登録日2005-12-13
公開日2006-05-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell.
Nucleic Acids Res., 34, 2006
2FCX
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BU of 2fcx by Molmil
HIV-1 DIS kissing-loop in complex with neamine
分子名称: (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, CHLORIDE ION, HIV-1 DIS RNA, ...
著者Ennifar, E, Paillart, J.C, Marquet, R, Dumas, P.
登録日2005-12-13
公開日2006-05-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell.
Nucleic Acids Res., 34, 2006
2BR2
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BU of 2br2 by Molmil
RNase PH core of the archaeal exosome
分子名称: CHLORIDE ION, EXOSOME COMPLEX EXONUCLEASE 1, EXOSOME COMPLEX EXONUCLEASE 2
著者lorentzen, E, Fribourg, S, Conti, E.
登録日2005-04-30
公開日2005-06-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Archaeal Exosome Core is a Hexameric Ring Structure with Three Catalytic Subunits.
Nat.Struct.Mol.Biol., 12, 2005
5W0T
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BU of 5w0t by Molmil
Crystal structure of monomeric Msp1 from S. cerevisiae
分子名称: 1,2-ETHANEDIOL, Protein MSP1
著者Keenan, R.J, Wohlever, M.L, Mateja, A.M.
登録日2017-05-31
公開日2017-08-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Msp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins.
Mol. Cell, 67, 2017
2J45
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BU of 2j45 by Molmil
Water structure of T. Aquaticus Ffh NG Domain At 1.1A Resolution
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Freymann, D.M, Ramirez, U.D.
登録日2006-08-24
公開日2006-11-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Analysis of Protein Hydration in Ultra-High Resolution Structures of the Srp Gtpase Ffh
Acta Crystallogr.,Sect.D, 62, 2006

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