2BE1

Structure of the compact lumenal domain of yeast Ire1

Summary for 2BE1

Entry DOI	10.2210/pdb2be1/pdb
Descriptor	Serine/threonine-protein kinase/endoribonuclease IRE1, peptide (3 entities in total)
Functional Keywords	peptide-binding groove peptide-mediated oligomerization beta-propeller, transcription
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Cellular location	Endoplasmic reticulum membrane; Single-pass type I membrane protein: P32361
Total number of polymer chains	3
Total formula weight	77068.70
Authors	Credle, J.J.,Finer-Moore, J.S.,Papa, F.R.,Stroud, R.M.,Walter, P. (deposition date: 2005-10-21, release date: 2005-12-13, Last modification date: 2024-04-03)
Primary citation	Credle, J.J.,Finer-Moore, J.S.,Papa, F.R.,Stroud, R.M.,Walter, P. Inaugural Article: On the mechanism of sensing unfolded protein in the endoplasmic reticulum Proc.Natl.Acad.Sci.Usa, 102:18773-18784, 2005 Cited by PubMed: 16365312 DOI: 10.1073/pnas.0509487102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.983 Å)

Structure validation