Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4CKM
DownloadVisualize
BU of 4ckm by Molmil
Structure of the N-terminal domain of Leishmania SAS-6
分子名称: GLYCEROL, MAGNESIUM ION, SAS-6
著者van Breugel, M.
登録日2014-01-07
公開日2014-03-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of the SAS-6 cartwheel hub from Leishmania major.
Elife, 3, 2014
3SLA
DownloadVisualize
BU of 3sla by Molmil
X-ray structure of first four repeats of human beta-catenin
分子名称: Catenin beta-1, GLYCEROL, SODIUM ION
著者Gupta, D, Bienz, M.
登録日2011-06-24
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
3SL9
DownloadVisualize
BU of 3sl9 by Molmil
X-ray structure of Beta catenin in complex with Bcl9
分子名称: 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ...
著者Gupta, D, Bienz, M.
登録日2011-06-24
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
5A7B
DownloadVisualize
BU of 5a7b by Molmil
Structure of the p53 cancer Y220C bound to the stabilizing small molecule PhiKan5211
分子名称: 2-[[4-(diethylamino)piperidin-1-yl]methyl]-6-ethynyl-4-(3-phenoxyprop-1-ynyl)phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C.
登録日2015-07-03
公開日2015-09-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen Bioisostere.
Acs Chem.Biol., 10, 2015
5SUZ
DownloadVisualize
BU of 5suz by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: C-centered monoclinic crystal form crystallised from monomeric fraction
分子名称: Segment polarity protein dishevelled homolog DVL-2
著者Renko, M, Gammons, M.V, Bienz, M.
登録日2016-08-04
公開日2016-10-12
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
5SUY
DownloadVisualize
BU of 5suy by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from dimeric fraction
分子名称: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
著者Renko, M, Gammons, M.V, Bienz, M.
登録日2016-08-04
公開日2016-10-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
2VUK
DownloadVisualize
BU of 2vuk by Molmil
Structure of the p53 core domain mutant Y220C bound to the stabilizing small-molecule drug PhiKan083
分子名称: 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Boeckler, F.M, Fersht, A.R.
登録日2008-05-26
公開日2008-07-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Targeted Rescue of a Destabilized Mutant of P53 by an in Silico Screened Drug.
Proc.Natl.Acad.Sci.USA, 105, 2008
2X0W
DownloadVisualize
BU of 2x0w by Molmil
STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 5,6-dimethoxy- 2-methylbenzothiazole
分子名称: 5,6-DIMETHOXY-2-METHYL-1,3-BENZOTHIAZOLE, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Kaar, J.L, Basse, N, Joerger, A.C, Fersht, A.R.
登録日2009-12-17
公開日2010-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant.
Chem.Biol., 17, 2010
2X0U
DownloadVisualize
BU of 2x0u by Molmil
STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-amino substituted benzothiazole scaffold
分子名称: 6,7-DIHYDRO[1,4]DIOXINO[2,3-F][1,3]BENZOTHIAZOL-2-AMINE, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Kaar, J.L, Basse, N, Fersht, A.R.
登録日2009-12-17
公開日2010-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant.
Chem.Biol., 17, 2010
2X0V
DownloadVisualize
BU of 2x0v by Molmil
STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-(trifluoromethyl)benzene-1,2-diamine
分子名称: 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Basse, N, Kaar, J.L, Joerger, A.C, Fersht, A.R.
登録日2009-12-17
公開日2010-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant.
Chem.Biol., 17, 2010
2W0T
DownloadVisualize
BU of 2w0t by Molmil
Solution structure of the FCS zinc finger domain of human LMBL2
分子名称: LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE 2 PROTEIN, ZINC ION
著者Lechtenberg, B.C, Allen, M.D, Bycroft, M.
登録日2008-10-10
公開日2009-01-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the Fcs Zinc Finger Domain of the Human Polycomb Group Protein L(3)Mbt-Like 2.
Protein Sci., 18, 2009
<123

 

225946

件を2024-10-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon