5WAM
 
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5WAQ
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7K3D
 | | The structure of NTMT1 in complex with compound DC1-13 | | 分子名称: | N-terminal Xaa-Pro-Lys N-methyltransferase 1, N~2~-{(2S)-1-[(naphthalen-1-yl)acetyl]-2,5-dihydro-1H-pyrrole-2-carbonyl}-L-lysyl-L-argininamide, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Chen, D, Huang, R, Noinaj, N. | | 登録日 | 2020-09-11 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Structure-based Discovery of Cell-Potent Peptidomimetic Inhibitors for Protein N-Terminal Methyltransferase 1.
Acs Med.Chem.Lett., 12, 2021
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7JRK
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7JRD
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5DYH
 | | Ti(IV) bound human serum transferrin | | 分子名称: | CARBONATE ION, CITRIC ACID, Serotransferrin, ... | | 著者 | Saxena, M, Sharma, S, Noinaj, N, Parks, T.B, Tinoco, A.D. | | 登録日 | 2015-09-24 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.682 Å) | | 主引用文献 | Unusual Synergism of Transferrin and Citrate in the Regulation of Ti(IV) Speciation, Transport, and Toxicity.
J.Am.Chem.Soc., 138, 2016
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6OV1
 | | Structure of Staphylococcus aureus RNase P protein mutant with defective mRNA degradation activity | | 分子名称: | Ribonuclease P protein component | | 著者 | Ha, L, Colquhoun, J, Noinaj, N, Das, C, Dunman, P, Flaherty, D.P. | | 登録日 | 2019-05-06 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Genetic and biochemical characterization of Staphylococcus aureus RnpA
To Be Published
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7SOK
 | | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor II329 | | 分子名称: | (2S)-2-amino-4-([3-(3-carbamoylphenyl)prop-2-yn-1-yl]{[(1R,2R,3S,4R)-4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl]methyl}amino)butanoic acid, DI(HYDROXYETHYL)ETHER, NNMT protein | | 著者 | Yadav, R, Iyamu, I.D, Huang, R, Noinaj, N. | | 登録日 | 2021-10-31 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor II329
To Be Published
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7SS1
 | | The structure of NTMT1 in complex with compound GD433 | | 分子名称: | (1R,3S,4R)-1-azabicyclo[2.2.2]octan-3-yl {2-[2-(4-fluoro-3-hydroxyphenyl)-1,3-thiazol-4-yl]propan-2-yl}carbamate, N-terminal Xaa-Pro-Lys N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Yadav, R, Guangping, D, Deng, Y, Huang, R, Noinaj, N. | | 登録日 | 2021-11-09 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Discovery of a first-in-class small molecule inhibitor for Protein N-terminal methyltransferases 1/2
To Be Published
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5SV0
 | | Structure of the ExbB/ExbD complex from E. coli at pH 7.0 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Biopolymer transport protein ExbB, CALCIUM ION | | 著者 | Celia, H, Botos, I, Lloubes, R, Buchanan, S.K, Noinaj, N. | | 登録日 | 2016-08-04 | | 公開日 | 2016-09-28 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insight into the role of the Ton complex in energy transduction.
Nature, 538, 2016
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5SV1
 | | Structure of the ExbB/ExbD complex from E. coli at pH 4.5 | | 分子名称: | Biopolymer transport protein ExbB, Biopolymer transport protein ExbD, MERCURY (II) ION | | 著者 | Celia, H, Botos, I, Lloubes, R, Buchanan, S.K, Noinaj, N. | | 登録日 | 2016-08-04 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural insight into the role of the Ton complex in energy transduction.
Nature, 538, 2016
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8DN7
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8DN6
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5EKQ
 | | The structure of the BamACDE subcomplex from E. coli | | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamC, Outer membrane protein assembly factor BamD, ... | | 著者 | Bakelar, J, Buchanan, S.K, Noinaj, N. | | 登録日 | 2015-11-04 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.392 Å) | | 主引用文献 | The structure of the beta-barrel assembly machinery complex.
Science, 351, 2016
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4EXM
 | | The crystal structure of an engineered phage lysin containing the binding domain of pesticin and the killing domain of T4-lysozyme | | 分子名称: | Pesticin, Lysozyme Chimera | | 著者 | Seddiki, N, Noinaj, N, Fairman, J.W, Lukacik, P, Barnard, T.J, Buchanan, S.K. | | 登録日 | 2012-04-30 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural engineering of a phage lysin that targets Gram-negative pathogens.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4E1S
 | | X-ray crystal structure of the transmembrane beta-domain from intimin from EHEC strain O157:H7 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, ... | | 著者 | Fairman, J.W, Dautin, N, Wojtowicz, D, Wei, L, Noinaj, N, Barnard, T.J, Udho, E, Finkelstein, A, Przytycka, T.M, Cherezov, V, Buchanan, S.K. | | 登録日 | 2012-03-07 | | 公開日 | 2012-06-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.855 Å) | | 主引用文献 | Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis.
Structure, 20, 2012
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4E1T
 | | X-ray crystal structure of the transmembrane beta-domain from invasin from Yersinia pseudotuberculosis | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Invasin | | 著者 | Fairman, J.W, Dautin, N, Wojtowicz, D, Wei, L, Noinaj, N, Barnard, T.J, Udho, E, Finkelstein, A, Przytycka, T.M, Cherezov, V, Buchanan, S.K. | | 登録日 | 2012-03-07 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.263 Å) | | 主引用文献 | Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis.
Structure, 20, 2012
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4EPI
 | | The crystal structure of pesticin-T4 lysozyme hybrid stabilized by engineered disulfide bonds | | 分子名称: | Pesticin, Lysozyme Chimera, SODIUM ION, ... | | 著者 | Seddiki, N, Fairman, J.W, Noinaj, N, Lukacik, P, Barnard, T, Buchanan, S.K. | | 登録日 | 2012-04-17 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structural engineering of a phage lysin that targets Gram-negative pathogens.
Proc.Natl.Acad.Sci.USA, 109, 2012
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7RKL
 | | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with II399 (P1 space group) | | 分子名称: | 3-[3-(acetyl{[(1R,2R,3S,4R)-4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl]methyl}amino)prop-1-yn-1-yl]benzamide, NNMT protein, SULFATE ION | | 著者 | Yadav, R, Noinaj, N, Iyamu, I.D, Huang, R. | | 登録日 | 2021-07-22 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Exploring Unconventional SAM Analogues To Build Cell-Potent Bisubstrate Inhibitors for Nicotinamide N-Methyltransferase.
Angew.Chem.Int.Ed.Engl., 61, 2022
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7RKK
 | | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with II399 (C2 space group) | | 分子名称: | 3-[3-(acetyl{[(1R,2R,3S,4R)-4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl]methyl}amino)prop-1-yn-1-yl]benzamide, NNMT protein | | 著者 | Yadav, R, Noinaj, N, Iyamu, I.D, Huang, R. | | 登録日 | 2021-07-22 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Exploring Unconventional SAM Analogues To Build Cell-Potent Bisubstrate Inhibitors for Nicotinamide N-Methyltransferase.
Angew.Chem.Int.Ed.Engl., 61, 2022
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3SLJ
 | | Pre-cleavage Structure of the Autotransporter EspP - N1023A mutant | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Serine protease espP | | 著者 | Barnard, T.B, Noinaj, N, Easley, N.C, Kuszak, A.J, Buchanan, S.K. | | 登録日 | 2011-06-24 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.481 Å) | | 主引用文献 | Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter.
J.Mol.Biol., 415, 2012
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8EPI
 | | Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands | | 分子名称: | DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*A)-3'), DNA (5'-D(P*TP*CP*CP*TP*A)-3') | | 著者 | Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C. | | 登録日 | 2022-10-05 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
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8EPE
 | | Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands | | 分子名称: | DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(P*CP*CP*CP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*G)-3') | | 著者 | Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C. | | 登録日 | 2022-10-05 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
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8EPB
 | | Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands | | 分子名称: | DNA (5'-D(*CP*GP*CP*TP*GP*GP*TP*GP*GP*TP*TP*CP*GP*A)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*GP*CP*CP*GP*AP*AP*CP*CP*T)-3') | | 著者 | Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C. | | 登録日 | 2022-10-05 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
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8EPD
 | | Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands | | 分子名称: | DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*GP*C)-3') | | 著者 | Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C. | | 登録日 | 2022-10-05 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
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