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9CYS
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BU of 9cys by Molmil
Toxin/immunity complex for a T6SS lipase effector from E. cloacae
分子名称: Ankyrin repeat domain-containing protein, CITRIC ACID, GLYCEROL, ...
著者Cuthbert, B.J, Jensen, S.J, Goulding, C.W, Hayes, C.S.
登録日2024-08-02
公開日2024-08-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Advanced glycation end-product (AGE) crosslinking activates a type 6 secretion system phospholipase effector protein
Nature Communications, 2024
6JPE
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BU of 6jpe by Molmil
Crystal structure of FGFR4 kinase domain with irreversible inhibitor 1
分子名称: Fibroblast growth factor receptor 4, N-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamide, SULFATE ION
著者Chen, X, Dai, S, Zhou, Z, Chen, Y.
登録日2019-03-26
公開日2020-05-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma.
J.Med.Chem., 63, 2020
8EM5
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BU of 8em5 by Molmil
Mycobacterium thermoresistible MmpS5
分子名称: DODECAETHYLENE GLYCOL, GLYCEROL, IODIDE ION, ...
著者Cuthbert, B.J, Goulding, C.W.
登録日2022-09-26
公開日2023-09-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The structure of Mycobacterium thermoresistibile MmpS5 reveals a conserved disulfide bond across mycobacteria.
Metallomics, 16, 2024
7UQ0
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BU of 7uq0 by Molmil
Putative periplasmic iron siderophore binding protein FecB (Rv3044) from Mycobacterium tuberculosis
分子名称: CITRIC ACID, GLYCEROL, PENTAETHYLENE GLYCOL, ...
著者Chao, A, Cuthbert, B.J, Goulding, C.W.
登録日2022-04-18
公開日2022-10-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake.
Plos Pathog., 19, 2023
6PLE
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BU of 6ple by Molmil
Crystal structure of MhuD R26S mutant in complex with biliverdin
分子名称: BILIVERDINE IX ALPHA, Heme oxygenase (mycobilin-producing)
著者Chao, A, Goulding, C.W.
登録日2019-06-30
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of aMycobacterium tuberculosisHeme-Degrading Protein, MhuD, Variant in Complex with Its Product.
Biochemistry, 58, 2019
6Q7M
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BU of 6q7m by Molmil
Spiral structure of E. coli RavA in the RavA-LdcI cage-like complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase RavA, Inducible lysine decarboxylase, ...
著者Arragain, B, Felix, J, Malet, H, Gutsche, I, Jessop, M.
登録日2018-12-13
公開日2020-02-12
最終更新日2020-02-19
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
6Q7L
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BU of 6q7l by Molmil
Spiral structure of E. coli RavA in the RavA-LdcI cage-like complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase RavA, Inducible lysine decarboxylase, ...
著者Arragain, B, Felix, J, Malet, H, Gutsche, I, Jessop, M.
登録日2018-12-13
公開日2020-02-12
最終更新日2020-02-19
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
6SZB
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BU of 6szb by Molmil
MoxR AAA-ATPase RavA, spiral open ring conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, RavA + Mg-ADP
著者Jessop, M, Felix, J, Gutsche, I.
登録日2019-10-02
公開日2020-02-19
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
6SZA
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BU of 6sza by Molmil
MoxR AAA-ATPase RavA, C2-symmetric closed ring conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, RavA
著者Jessop, M, Felix, J, Gutsche, I.
登録日2019-10-02
公開日2020-02-19
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
3B5B
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BU of 3b5b by Molmil
Crystal structure of the thymidylate synthase k48q
分子名称: 2'-DEOXY-5-NITROURIDINE 5'-(DIHYDROGEN PHOSPHATE), 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, FORMIC ACID, ...
著者Sotelo-Mundo, R.R, Arreola, R, Maley, F, Montfort, W.R.
登録日2007-10-25
公開日2007-12-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Role of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: Calorimetric and crystallographic analysis of the K48Q mutant.
Int.J.Biochem.Cell Biol., 40, 2008
2VF0
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BU of 2vf0 by Molmil
CRYSTAL STRUCTURE OF THE THYMIDYLATE SYNTHASE K48Q COMPLEXED WITH 5NO2DUMP AND BW1843U89
分子名称: 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID, SULFATE ION, ...
著者Sotelo-Mundo, R.R, Arreola, R, Maley, F, Montfort, W.R.
登録日2007-10-27
公開日2007-12-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Role of an Invariant Lysine Residue in Folate Binding on Escherichia Coli Thymidylate Synthase: Calorimetric and Crystallographic Analysis of the K48Q Mutant.
Int.J.Biochem.Cell Biol., 40, 2008
2VET
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BU of 2vet by Molmil
CRYSTAL STRUCTURE OF THE THYMIDYLATE SYNTHASE K48Q COMPLEXED WITH DUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Sotelo-Mundo, R.R, Arreola, R, Maley, F, Montfort, W.R.
登録日2007-10-26
公開日2007-12-04
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Role of an Invariant Lysine Residue in Folate Binding on Escherichia Coli Thymidylate Synthase: Calorimetric and Crystallographic Analysis of the K48Q Mutant.
Int.J.Biochem.Cell Biol., 40, 2008
1JIC
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BU of 1jic by Molmil
SOLUTION NMR STRUCTURE OF RECOMBINANT SSO7D WITH RNASE ACTIVITY, MINIMIZED AVERAGE STRUCTURE
分子名称: SSO7D
著者Consonni, R, Santomo, L, Zetta, L.
登録日1998-07-20
公開日1998-10-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A single-point mutation in the extreme heat- and pressure-resistant sso7d protein from sulfolobus solfataricus leads to a major rearrangement of the hydrophobic core.
Biochemistry, 38, 1999
3FLO
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BU of 3flo by Molmil
Crystal structure of the carboxyl-terminal domain of yeast DNA polymerase alpha in complex with its B subunit
分子名称: DNA polymerase alpha catalytic subunit A, DNA polymerase alpha subunit B, SULFATE ION, ...
著者Klinge, S.N, Pellegrini, L.
登録日2008-12-19
公開日2009-06-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases
Embo J., 28, 2009
1PD5
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BU of 1pd5 by Molmil
Crystal structure of E.coli chloramphenicol acetyltransferase type I at 2.5 Angstrom resolution
分子名称: Chloramphenicol acetyltransferase
著者Roidis, A, Kokkinidis, M.
登録日2003-05-19
公開日2004-06-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of E.coli chloramphenicol acetyltransferase type I at 2.5 Angstrom resolution
To be Published
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