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8GRE
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BU of 8gre by Molmil
F-box protein in complex with skp1(FL) and substrate
分子名称: Citrate synthase, E3 ubiquitin ligase complex SCF subunit, F-box protein UCC1, ...
著者Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T.
登録日2022-09-01
公開日2023-04-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
8GQZ
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BU of 8gqz by Molmil
Crystal structure of mitochondrial citrate synthase (Cit1) from Saccharomyces cerevisiae
分子名称: ACETATE ION, CHLORIDE ION, Citrate synthase, ...
著者Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T.
登録日2022-08-31
公開日2023-04-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
8GRF
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BU of 8grf by Molmil
Crystal structure of F-box protein in the ternary complex with adaptor protein Skp1(DL) and its substrate
分子名称: 1,2-ETHANEDIOL, Citrate synthase, E3 ubiquitin ligase complex SCF subunit, ...
著者Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T.
登録日2022-09-01
公開日2023-04-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
8H7X
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BU of 8h7x by Molmil
Crystal structure of EGFR T790M/C797S mutant in complex with brigatinib
分子名称: 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine, Epidermal growth factor receptor
著者Kukimoto-Niino, M, Shirouzu, M.
登録日2022-10-21
公開日2023-10-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.404 Å)
主引用文献A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer.
NPJ Precis Oncol, 8, 2024
5B24
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BU of 5b24 by Molmil
The crystal structure of the nucleosome containing cyclobutane pyrimidine dimer
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Horikoshi, N, Tachiwana, H, Kagawa, W, Osakabe, A, Kurumizaka, H.
登録日2015-12-31
公開日2016-03-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Crystal structure of the nucleosome containing ultraviolet light-induced cyclobutane pyrimidine dimer
Biochem.Biophys.Res.Commun., 471, 2016
2ZDT
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BU of 2zdt by Molmil
Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor
分子名称: 4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2(1H)-yl)methyl]benzoic acid, GLYCEROL, Mitogen-activated protein kinase 10
著者Sogabe, S, Asano, Y, Fukumoto, S, Habuka, N, Fujishima, A.
登録日2007-11-27
公開日2008-09-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2)
Bioorg.Med.Chem., 16, 2008
2ZDU
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BU of 2zdu by Molmil
Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor
分子名称: 4-[(4-{[6-bromo-3-(methoxycarbonyl)-1-oxo-4-phenylisoquinolin-2(1H)-yl]methyl}phenyl)amino]-4-oxobutanoic acid, Mitogen-activated protein kinase 10
著者Sogabe, S, Ohra, T, Itoh, F, Habuka, N, Fujishima, A.
登録日2007-11-27
公開日2008-09-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1)
Bioorg.Med.Chem., 16, 2008
7E0G
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BU of 7e0g by Molmil
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418, FAD-adduct
分子名称: GLYCEROL, IMIDAZOLE, Lysine-specific histone demethylase 1A, ...
著者Oki, H.
登録日2021-01-28
公開日2021-03-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models.
Sci Adv, 7, 2021
4FXC
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BU of 4fxc by Molmil
TERTIARY STRUCTURE OF [2FE-2S] FERREDOXIN FROM SPIRULINA PLATENSIS REFINED AT 2.5 ANGSTROMS RESOLUTION: STRUCTURAL COMPARISONS OF PLANT-TYPE FERREDOXINS AND AN ELECTROSTATIC POTENTIAL ANALYSIS
分子名称: FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN
著者Fukuyama, K, Tsukihara, T.
登録日1995-04-25
公開日1995-12-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tertiary structure of [2Fe-2S] ferredoxin from Spirulina platensis refined at 2.5 A resolution: structural comparisons of plant-type ferredoxins and an electrostatic potential analysis.
J.Biochem.(Tokyo), 117, 1995
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件を2024-07-31に公開中

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