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9F44
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BU of 9f44 by Molmil
cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1
分子名称: INOSITOL HEXAKISPHOSPHATE, Lateral signaling target protein 2 homolog, Regulatory-associated protein of mTOR, ...
著者Craigie, L.M, Maier, T.
登録日2024-04-26
公開日2024-08-14
最終更新日2024-08-28
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Proc.Natl.Acad.Sci.USA, 121, 2024
9F45
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BU of 9f45 by Molmil
cryo-EM structure of human LST2 bound to human mTOR complex 1
分子名称: INOSITOL HEXAKISPHOSPHATE, Lateral signaling target protein 2 homolog, Regulatory-associated protein of mTOR, ...
著者Craigie, L.M, Maier, T.
登録日2024-04-26
公開日2024-08-14
最終更新日2024-08-28
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Proc.Natl.Acad.Sci.USA, 121, 2024
1OID
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BU of 1oid by Molmil
5'-Nucleotidase (E. coli) with an Engineered Disulfide Bridge (S228C, P513C)
分子名称: NICKEL (II) ION, PROTEIN USHA
著者Schultz-Heienbrok, R, Maier, T, Straeter, N.
登録日2003-06-13
公開日2004-06-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Trapping a 96 Degree Domain Rotation in Two Distinct Conformations by Engineered Disulfide Bridges
Protein Sci., 13, 2004
1OI8
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BU of 1oi8 by Molmil
5'-Nucleotidase (E. coli) with an Engineered Disulfide Bridge (P90C, L424C)
分子名称: CARBONATE ION, MANGANESE (II) ION, PROTEIN USHA, ...
著者Schultz-Heienbrok, R, Maier, T, Straeter, N.
登録日2003-06-10
公開日2004-06-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Trapping a 96 Degree Domain Rotation in Two Distinct Conformations by Engineered Disulfide Bridges
Protein Sci., 13, 2004
1OIE
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BU of 1oie by Molmil
5'-Nucleotidase (E. coli) with an Engineered Disulfide Bridge (S228C, P513C)
分子名称: NICKEL (II) ION, PROTEIN USHA
著者Schultz-Heienbrok, R, Maier, T, Straeter, N.
登録日2003-06-16
公開日2004-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Trapping a 96 Degree Domain Rotation in Two Distinct Conformations by Engineered Disulfide Bridges
Protein Sci., 13, 2004
2Z9A
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BU of 2z9a by Molmil
Crystal Structure of Human Saposin C Dimer in Open Conformation
分子名称: GLYCEROL, Proactivator polypeptide
著者Rossmann, M, Saenger, W, Maier, T.
登録日2007-09-18
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
5MXN
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BU of 5mxn by Molmil
Atomic model of the VipA/VipB/Hcp, the type six secretion system non-contractile sheath-tube of Vibrio cholerae from cryo-EM
分子名称: Haemolysin co-regulated protein, Type VI secretion protein
著者Wang, J, Brackmann, M, Castano-Diez, D, Kudryashev, M, Goldie, K, Maier, T, Stahlberg, H, Basler, M.
登録日2017-01-23
公開日2017-08-02
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Nat Microbiol, 2, 2017
5NH1
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BU of 5nh1 by Molmil
Structure of the C-terminal domain of human Gasdermin D
分子名称: Gasdermin-D
著者Anton, L, Sborgi, L, Hiller, S, Broz, P, Maier, T.
登録日2017-03-21
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Insights into Gasdermin D activation from the crystal structure of its C-terminal domain
Biorxiv, 2017
5OJQ
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BU of 5ojq by Molmil
The modeled structure of of wild type extended type VI secretion system sheath/tube complex in vibrio cholerae based on cryo-EM reconstruction of the non-contractile sheath/tube complex
分子名称: Haemolysin co-regulated protein, Type VI secretion protein, VipA
著者Wang, J, Brackmann, M, Castano-Diez, D, Kudryashev, M, Goldie, K, Maier, T, Stahlberg, H, Basler, M.
登録日2017-07-22
公開日2017-08-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Nat Microbiol, 2, 2017
1CE7
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BU of 1ce7 by Molmil
MISTLETOE LECTIN I FROM VISCUM ALBUM
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (RIBOSOME-INACTIVATING PROTEIN TYPE II)
著者Krauspenhaar, R, Eschenburg, S, Perbandt, M, Kornilov, V, Konareva, N, Mikailova, I, Stoeva, S, Wacker, R, Maier, T, Singh, T.P, Mikhailov, A, Voelter, W, Betzel, C.
登録日1999-03-18
公開日2000-03-20
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of mistletoe lectin I from Viscum album.
Biochem.Biophys.Res.Commun., 257, 1999
4TM8
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BU of 4tm8 by Molmil
Crystal structure of 6-phosphogluconolactonase from Mycobacterium smegmatis N131D mutant
分子名称: 6-phosphogluconolactonase, SULFATE ION
著者Fujieda, N, Stuttfeld, E, Maier, T.
登録日2014-05-31
公開日2015-06-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Enzyme repurposing of a hydrolase as an emergent peroxidase upon metal binding.
Chem Sci, 6, 2015
4TM7
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BU of 4tm7 by Molmil
Crystal structure of 6-phosphogluconolactonase from Mycobacterium smegmatis N131D mutant soaked with CuSO4
分子名称: 1,2-ETHANEDIOL, 6-phosphogluconolactonase, CHLORIDE ION, ...
著者Fujieda, N, Stuttfeld, E, Maier, T.
登録日2014-05-31
公開日2015-06-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Enzyme repurposing of a hydrolase as an emergent peroxidase upon metal binding.
Chem Sci, 6, 2015
5MYU
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BU of 5myu by Molmil
VipA-N2/VipB contracted sheath of type VI secretion system
分子名称: Type VI secretion system protein ImpC, Uncharacterized protein
著者Wang, J, Brackmann, B, Castano-Diez, D, Kudryashev, M, Goldie, D, Maier, T, Stahlberg, H, Basler, M.
登録日2017-01-27
公開日2017-08-02
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Nat Microbiol, 2, 2017
5OOW
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BU of 5oow by Molmil
Crystal structure of lobe II from the nucleotide binding domain of DnaK in complex with AMPPCP
分子名称: Chaperone protein DnaK, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Jakob, R.P, Bauer, D, Meinhold, S, Stigler, J, Merkel, U, Maier, T, Rief, M, Zoldak, G.
登録日2017-08-09
公開日2018-04-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A folding nucleus and minimal ATP binding domain of Hsp70 identified by single-molecule force spectroscopy.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4CSS
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BU of 4css by Molmil
Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside
分子名称: 4'-(alpha-D-Mannopyranosyloxy)-biphenyl-4-methyl sulfonamide, GLYCEROL, PROTEIN FIMH
著者Kleeb, S, Pang, L, Mayer, K, Sigl, A, Eris, D, Preston, R.C, Zihlmann, P, Abgottspon, D, Hutter, A, Scharenberg, M, Jian, X, Navarra, G, Rabbani, S, Smiesko, M, Luedin, N, Jakob, R.P, Schwardt, O, Maier, T, Sharpe, T, Ernst, B.
登録日2014-03-10
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.069 Å)
主引用文献Fimh Antagonists: Bioisosteres to Improve the in Vitro and in Vivo Pk/Pd Profile.
J.Med.Chem., 58, 2015
4CST
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BU of 4cst by Molmil
Crystal structure of FimH in complex with 3'-Chloro-4'-(alpha-D-mannopyranosyloxy)-biphenyl-4-carbonitrile
分子名称: 3'-chloro-4'-(alpha-D-mannopyranosyloxy)biphenyl-4-carbonitrile, PROTEIN FIMH
著者Kleeb, S, Pang, L, Mayer, K, Sigl, A, Eris, D, Preston, R.C, Zihlmann, P, Abgottspon, D, Hutter, A, Scharenberg, M, Jian, X, Navarra, G, Rabbani, S, Smiesko, M, Luedin, N, Jakob, R.P, Schwardt, O, Maier, T, Sharpe, T, Ernst, B.
登録日2014-03-10
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Fimh Antagonists: Bioisosteres to Improve the in Vitro and in Vivo Pk/Pd Profile.
J.Med.Chem., 58, 2015
4WO7
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BU of 4wo7 by Molmil
Crystal Structure of PrsA from Bacillus subtilis
分子名称: Foldase protein PrsA
著者Jakob, R.P, Maier, T.
登録日2014-10-15
公開日2014-12-24
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Dimeric Structure of the Bacterial Extracellular Foldase PrsA.
J.Biol.Chem., 290, 2015
4X5R
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BU of 4x5r by Molmil
Crystal structure of FimH in complex with a squaryl-phenyl alpha-D-mannopyranoside derivative
分子名称: 2-chloro-4-{[2-(4-methylpiperazin-1-yl)-3,4-dioxocyclobut-1-en-1-yl]amino}phenyl alpha-D-mannopyranoside, Protein FimH, SULFATE ION
著者Preston, R.C, Jakob, R.P, Fiege, B, Zihlmann, P, Rabbani, S, Schwardt, O, Jiang, X, Ernst, B, Maier, T.
登録日2014-12-05
公開日2015-05-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X-ray Crystallography.
Chembiochem, 16, 2015
4X5P
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BU of 4x5p by Molmil
Crystal structure of FimH in complex with a benzoyl-amidophenyl alpha-D-mannopyranoside
分子名称: 4-{[3-chloro-4-(alpha-D-mannopyranosyloxy)phenyl]carbamoyl}benzoic acid, Protein FimH
著者Preston, R.C, Jakob, R.P, Fiege, B, Zihlmann, P, Rabbani, S, Schwardt, O, Jiang, X, Ernst, B, Maier, T.
登録日2014-12-05
公開日2015-05-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (0.997 Å)
主引用文献The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X-ray Crystallography.
Chembiochem, 16, 2015
4X5Q
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BU of 4x5q by Molmil
Crystal structure of FimH in complex with 5-nitro-indolinylphenyl alpha-D-mannopyranoside
分子名称: 4-(5-nitro-1H-indol-1-yl)phenyl alpha-D-mannopyranoside, Protein FimH
著者Preston, R.C, Jakob, R.P, Fiege, B, Zihlmann, P, Rabbani, S, Schwardt, O, Jiang, X, Ernst, B, Maier, T.
登録日2014-12-05
公開日2015-05-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X-ray Crystallography.
Chembiochem, 16, 2015
4X50
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BU of 4x50 by Molmil
Crystal structure of FimH in complex with biphenyl alpha-D-mannopyranoside
分子名称: Protein FimH, biphenyl-4-yl alpha-D-mannopyranoside
著者Preston, R.C, Jakob, R.P, Fiege, B, Zihlmann, P, Rabbani, S, Schwardt, O, Jiang, X, Ernst, B, Maier, T.
登録日2014-12-04
公開日2015-05-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X-ray Crystallography.
Chembiochem, 16, 2015
4V5B
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BU of 4v5b by Molmil
Structure of PDF binding helix in complex with the ribosome.
分子名称: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Bingel-Erlenmeyer, R, Kohler, R, Kramer, G, Sandikci, A, Antolic, S, Maier, T, Schaffitzel, C, Wiedmann, B, Bukau, B, Ban, N.
登録日2007-11-22
公開日2014-07-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.74 Å)
主引用文献A Peptide Deformylase-Ribosome Complex Reveals Mechanism of Nascent Chain Processing.
Nature, 452, 2008
4XO9
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BU of 4xo9 by Molmil
Crystal structure of a FimH*DsG complex from E.coli K12 in space group C2
分子名称: Minor component of type 1 fimbriae, Protein FimH
著者Jakob, R.P, Eras, J, Glockshuber, R, Maier, T.
登録日2015-01-16
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Catch-bond mechanism of the bacterial adhesin FimH.
Nat Commun, 7, 2016
4XO8
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Crystal structure of the FimH lectin domain from E.coli K12 in complex with heptyl alpha-D-mannopyrannoside
分子名称: Protein FimH, heptyl alpha-D-mannopyranoside
著者Jakob, R.P, Eras, J, Navarra, G, Ernst, B, Glockshuber, R, Maier, T.
登録日2015-01-16
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Catch-bond mechanism of the bacterial adhesin FimH.
Nat Commun, 7, 2016
4CW5
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BU of 4cw5 by Molmil
Crystal structure of the enoyl reductase domain of DfnA from Bacillus amyloliquefaciens
分子名称: DFNA, FLAVIN MONONUCLEOTIDE
著者Jakob, R.P, Buhkari, H.S.T, Maier, T.
登録日2014-04-01
公開日2014-12-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Evolutionary Origins of the Multienzyme Architecture of Giant Fungal Fatty Acid Synthase.
Structure, 22, 2014

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