1OTT
 
 | | Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex | | 分子名称: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | | 著者 | Dutzler, R, Campbell, E.B, MacKinnon, R. | | 登録日 | 2003-03-23 | | 公開日 | 2003-04-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
|
|
1BFE
 | | THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 | | 分子名称: | PSD-95 | | 著者 | Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R. | | 登録日 | 1998-05-20 | | 公開日 | 1998-10-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
|
|
1LNQ
 | | CRYSTAL STRUCTURE OF MTHK AT 3.3 A | | 分子名称: | CALCIUM ION, POTASSIUM CHANNEL RELATED PROTEIN | | 著者 | Jiang, Y, Lee, A, Chen, J, Cadene, M, Chait, B.T, Mackinnon, R. | | 登録日 | 2002-05-03 | | 公開日 | 2002-06-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | CRYSTAL STRUCTURE AND MECHANISM OF A CALCIUM-GATED POTASSIUM CHANNEL
Nature, 417, 2002
|
|
3LNM
 | | F233W mutant of the Kv2.1 paddle-Kv1.2 chimera channel | | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, F233W mutant of the Kv2.1 paddle-Kv1.2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Tao, X, Lee, A, Limapichat, W, Dougherty, D.A, MacKinnon, R. | | 登録日 | 2010-02-02 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A gating charge transfer center in voltage sensors.
Science, 328, 2010
|
|
3MT5
 | |
3ORG
 | |
1R3J
 | | potassium channel KcsA-Fab complex in high concentration of Tl+ | | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | | 著者 | Zhou, Y, MacKinnon, R. | | 登録日 | 2003-10-02 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
|
|
1R3L
 | | potassium channel KcsA-Fab complex in Cs+ | | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, CESIUM ION, ... | | 著者 | Zhou, Y, MacKinnon, R. | | 登録日 | 2003-10-02 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
|
|
1R3I
 | | potassium channel KcsA-Fab complex in Rb+ | | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | | 著者 | Zhou, Y, MacKinnon, R. | | 登録日 | 2003-10-02 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
|
|
1R3K
 | | potassium channel KcsA-Fab complex in low concentration of Tl+ | | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | | 著者 | Zhou, Y, MacKinnon, R. | | 登録日 | 2003-10-02 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
|
|
4JTD
 | | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin | | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... | | 著者 | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | | 登録日 | 2013-03-23 | | 公開日 | 2013-06-12 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
|
|
4JTC
 | | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+ | | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | | 登録日 | 2013-03-23 | | 公開日 | 2013-06-12 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
|
|
6B3R
 | |
6PBY
 | |
6PBX
 | |
6C3P
 | | Cryo-EM structure of human KATP bound to ATP and ADP in propeller form | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | 著者 | Lee, K.P.K, Chen, J, MacKinnon, R. | | 登録日 | 2018-01-10 | | 公開日 | 2018-01-24 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | Molecular structure of human KATP in complex with ATP and ADP.
Elife, 6, 2017
|
|
6C3O
 | | Cryo-EM structure of human KATP bound to ATP and ADP in quatrefoil form | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | 著者 | Lee, K.P.K, Chen, J, MacKinnon, R. | | 登録日 | 2018-01-10 | | 公開日 | 2018-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular structure of human KATP in complex with ATP and ADP
Elife, 6, 2017
|
|
6CNN
 | |
6COY
 | |
6CNO
 | |
6CNM
 | | Cryo-EM structure of the human SK4/calmodulin channel complex | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calmodulin-1, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Lee, C.H, MacKinnon, R. | | 登録日 | 2018-03-08 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science, 360, 2018
|
|
6COZ
 | |
4KFM
 | |
7S5Y
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | 著者 | Zhao, C, MacKinnon, R. | | 登録日 | 2021-09-12 | | 公開日 | 2021-12-01 | | 最終更新日 | 2021-12-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
1KPK
 | | Crystal Structure of the ClC Chloride Channel from E. coli | | 分子名称: | putative channel transporter | | 著者 | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | | 登録日 | 2001-12-31 | | 公開日 | 2002-01-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity.
Nature, 415, 2002
|
|
