4DHY
 
 | | Crystal structure of human glucokinase in complex with glucose and activator | | 分子名称: | Glucokinase, N,N-dimethyl-5-({2-methyl-6-[(5-methylpyrazin-2-yl)carbamoyl]-1-benzofuran-4-yl}oxy)pyrimidine-2-carboxamide, SODIUM ION, ... | | 著者 | Liu, S. | | 登録日 | 2012-01-30 | | 公開日 | 2012-02-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS.
J.Biol.Chem., 287, 2012
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6CPV
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5HI4
 | | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists | | 分子名称: | (9'S,17'R)-6'-chloro-N-methyl-9'-{[(1-methyl-1H-pyrazol-5-yl)carbonyl]amino}-10',19'-dioxo-2'-oxa-11',18'-diazaspiro[cyclopentane-1,21'-tetracyclo[20.2.2.2~12,15~.1~3,7~]nonacosane]-1'(24'),3'(29'),4',6',12',14',22',25',27'-nonaene-17'-carboxamide, CAT-2000 FAB heavy chain, CAT-2000 FAB light chain, ... | | 著者 | Liu, S. | | 登録日 | 2016-01-11 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists.
Sci Rep, 6, 2016
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3BLU
 | | crystal structure YopH complexed with inhibitor PVS | | 分子名称: | (ethenylsulfonyl)benzene, Tyrosine-protein phosphatase yopH | | 著者 | Liu, S, Zhang, Z.-Y. | | 登録日 | 2007-12-11 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases
J.Am.Chem.Soc., 130, 2008
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5HI5
 | | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists | | 分子名称: | (4S,20R)-7-chloro-N-methyl-4-{[(1-methyl-1H-pyrazol-5-yl)carbonyl]amino}-3,18-dioxo-2,19-diazatetracyclo[20.2.2.1~6,10~.1~11,15~]octacosa-1(24),6(28),7,9,11(27),12,14,22,25-nonaene-20-carboxamide, CAT-2000 FAB heavy chain, CAT-2000 light chain, ... | | 著者 | Liu, S. | | 登録日 | 2016-01-11 | | 公開日 | 2016-08-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists.
Sci Rep, 6, 2016
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1S2U
 | | Crystal structure of the D58A phosphoenolpyruvate mutase mutant protein | | 分子名称: | DI(HYDROXYETHYL)ETHER, Phosphoenolpyruvate phosphomutase | | 著者 | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | | 登録日 | 2004-01-11 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Conformational Flexibility of PEP Mutase
Biochemistry, 43, 2004
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5HI3
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1OQF
 | | Crystal structure of the 2-methylisocitrate lyase | | 分子名称: | 2-methylisocitrate lyase | | 著者 | Liu, S, Lu, Z, Dunaway-Mariano, D, Herzberg, O, Structure 2 Function Project (S2F) | | 登録日 | 2003-03-08 | | 公開日 | 2004-04-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Crystal structures of 2-methylisocitrate lyase in complex with product and with isocitrate inhibitor provide insight into lyase substrate specificity, catalysis and evolution.
Biochemistry, 44, 2005
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1S2W
 | | Crystal structure of phosphoenolpyruvate mutase in high ionic strength | | 分子名称: | Phosphoenolpyruvate phosphomutase, SULFATE ION | | 著者 | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | | 登録日 | 2004-01-11 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Conformational Flexibility of PEP Mutase
Biochemistry, 43, 2004
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1S2T
 | | Crystal Structure Of Apo Phosphoenolpyruvate Mutase | | 分子名称: | Phosphoenolpyruvate phosphomutase | | 著者 | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | | 登録日 | 2004-01-11 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Conformational Flexibility of PEP Mutase
Biochemistry, 43, 2004
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4LU9
 | | Crystal structure of E.coli SbcD at 2.5 angstrom resolution | | 分子名称: | Exonuclease subunit SbcD, GLYCEROL | | 著者 | Liu, S, Tian, L.F, Yan, X.X, Liang, D.C. | | 登録日 | 2013-07-25 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for DNA recognition and nuclease processing by the Mre11 homologue SbcD in double-strand breaks repair.
Acta Crystallogr.,Sect.D, 70, 2014
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1S2V
 | | Crystal structure of phosphoenolpyruvate mutase complexed with Mg(II) | | 分子名称: | MAGNESIUM ION, Phosphoenolpyruvate phosphomutase | | 著者 | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | | 登録日 | 2004-01-11 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformational Flexibility of PEP Mutase
Biochemistry, 43, 2004
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4M0V
 | | Crystal structure of E.coli SbcD with Mn2+ | | 分子名称: | Exonuclease subunit SbcD, GLYCEROL, MANGANESE (II) ION | | 著者 | Liu, S, Tian, L.F, Yan, X.X, Liang, D.C. | | 登録日 | 2013-08-02 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structural basis for DNA recognition and nuclease processing by the Mre11 homologue SbcD in double-strand breaks repair.
Acta Crystallogr.,Sect.D, 70, 2014
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3BLT
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4ZXA
 | | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Cd2+ and 4-hydroxybenzonitrile | | 分子名称: | 4-hydroxybenzonitrile, CADMIUM ION, Hydroquinone dioxygenase large subunit, ... | | 著者 | Liu, S, Su, T, Zhang, C, Gu, L. | | 登録日 | 2015-05-20 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.488 Å) | | 主引用文献 | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases.
J.Biol.Chem., 290, 2015
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4ZXD
 | | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD | | 分子名称: | Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit | | 著者 | Liu, S, Su, T, Zhang, C, Gu, L. | | 登録日 | 2015-05-20 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.052 Å) | | 主引用文献 | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases.
J.Biol.Chem., 290, 2015
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4ZXC
 | | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Fe3+ | | 分子名称: | FE (III) ION, Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit | | 著者 | Liu, S, Su, T, Zhang, C, Gu, L. | | 登録日 | 2015-05-20 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases.
J.Biol.Chem., 290, 2015
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5HHX
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6A96
 | | Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-5,Gamma-aminobutyric acid receptor subunit alpha-5, ... | | 著者 | Liu, S, Xu, L, Guan, F, Liu, Y.T, Cui, Y, Zhang, Q, Bi, G.Q, Zhou, Z.H, Zhang, X, Ye, S. | | 登録日 | 2018-07-11 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | | 主引用文献 | Cryo-EM structure of the human alpha 5 beta 3 GABAAreceptor.
Cell Res., 28, 2018
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8EQB
 | | FAM46C/BCCIPalpha/Nanobody complex | | 分子名称: | Isoform 2 of BRCA2 and CDKN1A-interacting protein, Synthetic nanobody 1, Terminal nucleotidyltransferase 5C | | 著者 | Liu, S, Chen, H, Yin, Y, Bai, X, Zhang, X. | | 登録日 | 2022-10-07 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-04-26 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | Inhibition of FAM46/TENT5 activity by BCCIP alpha adopting a unique fold.
Sci Adv, 9, 2023
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8EXE
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8EXF
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8FJP
 | | Cryo-EM structure of native mosquito salivary gland surface protein 1 (SGS1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, salivary gland surface protein 1 | | 著者 | Liu, S, Xia, X, Calvo, E, Zhou, Z.H. | | 登録日 | 2022-12-20 | | 公開日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Native structure of mosquito salivary protein uncovers domains relevant to pathogen transmission.
Nat Commun, 14, 2023
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5HHV
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3DYL
 | | human phosphdiesterase 9 substrate complex (ES complex) | | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, CYCLIC GUANOSINE MONOPHOSPHATE, FORMIC ACID, ... | | 著者 | Liu, S, Mansour, M.N, Dillman, K, Perez, J, Danley, D, Menniti, F. | | 登録日 | 2008-07-28 | | 公開日 | 2008-09-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for the catalytic mechanism of human phosphodiesterase 9.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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