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1OQF

Crystal structure of the 2-methylisocitrate lyase

Summary for 1OQF
Entry DOI10.2210/pdb1oqf/pdb
Descriptor2-methylisocitrate lyase (2 entities in total)
Functional Keywordsstructural genomics, alpha-beta barrel, swapped helix across a dimer, structure 2 function project, s2f, lyase
Biological sourceEscherichia coli
Total number of polymer chains2
Total formula weight64076.84
Authors
Liu, S.,Lu, Z.,Dunaway-Mariano, D.,Herzberg, O.,Structure 2 Function Project (S2F) (deposition date: 2003-03-08, release date: 2004-04-27, Last modification date: 2024-02-14)
Primary citationLiu, S.,Lu, Z.,Han, Y.,Melamud, E.,Dunaway-Mariano, D.,Herzberg, O.
Crystal structures of 2-methylisocitrate lyase in complex with product and with isocitrate inhibitor provide insight into lyase substrate specificity, catalysis and evolution.
Biochemistry, 44:2949-2962, 2005
Cited by
PubMed: 15723538
DOI: 10.1021/bi0479712
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.93 Å)
Structure validation

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