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5EII
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BU of 5eii by Molmil
Structural determination of an protein complex of a Fab with increased solubility
分子名称: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
著者Bailey, L.J, Kossiakoff, A.A, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)
登録日2015-10-29
公開日2016-11-09
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural determination of an protein complex of a Fab with increased solubility
To Be Published
1YIW
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BU of 1yiw by Molmil
X-ray Crystal Structure of a Chemically Synthesized Ubiquitin
分子名称: CADMIUM ION, CHLORIDE ION, Ubiquitin
著者Bang, D, Makhatadze, G.I, Tereshko, V, Kossiakoff, A.A, Kent, S.B.
登録日2005-01-13
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
Angew.Chem.Int.Ed.Engl., 44, 2005
1Y3T
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BU of 1y3t by Molmil
Crystal structure of YxaG, a dioxygenase from Bacillus subtilis
分子名称: FE (III) ION, Hypothetical protein yxaG
著者Gopal, B, Madan, L.L, Betz, S.F, Kossiakoff, A.A.
登録日2004-11-26
公開日2005-01-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of a Quercetin 2,3-Dioxygenase from Bacillus subtilis Suggests Modulation of Enzyme Activity by a Change in the Metal Ion at the Active Site(s)
Biochemistry, 44, 2005
6UKJ
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BU of 6ukj by Molmil
Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform
分子名称: CHOLESTEROL HEMISUCCINATE, Chloroquine resistance transporter, Fab Heavy Chain, ...
著者Kim, J, Tan, Y.Z, Wicht, K.J, Erramilli, S.K, Dhingra, S.K, Okombo, J, Vendome, J, Hagenah, L.M, Giacometti, S.I, Warren, A.L, Nosol, K, Roepe, P.D, Potter, C.S, Carragher, B, Kossiakoff, A.A, Quick, M, Fidock, D.A, Mancia, F.
登録日2019-10-05
公開日2019-12-04
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.
Nature, 576, 2019
6USF
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BU of 6usf by Molmil
CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor with varenicline in complex with anti-BRIL synthetic antibody BAK5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, ...
著者Alvarez, F.J.D, Mukherjee, S, Han, S, Ammirati, M, Kossiakoff, A.A.
登録日2019-10-26
公開日2020-04-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
6UR8
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BU of 6ur8 by Molmil
CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor in complex with varenicline
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chimera of soluble cytochrome b562 (BRIL) and neuronal acetylcholine receptor subunit alpha-4, Neuronal acetylcholine receptor subunit beta-2, ...
著者Alvarez, F.J.D, Mukherjee, S, Han, S, Ammirati, M, Kossiakoff, A.A.
登録日2019-10-22
公開日2020-04-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
4JQI
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BU of 4jqi by Molmil
Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide
分子名称: 1,2-ETHANEDIOL, Beta-arrestin-1, CHLORIDE ION, ...
著者Shukla, A.K, Manglik, A, Kruse, A.C, Xiao, K, Reis, R.I, Tseng, W.C, Staus, D.P, Hilger, D, Uysal, S, Huang, L.H, Paduch, M, Shukla, P.T, Koide, A, Koide, S, Weis, W.I, Kossiakoff, A.A, Kobilka, B.K, Lefkowitz, R.J.
登録日2013-03-20
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Nature, 497, 2013
3E7U
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BU of 3e7u by Molmil
X-ray Crystal Structure of L-Plectasin
分子名称: Plectasin
著者Mandal, K, Pentelute, B.L, Tereshko, V, Kossiakoff, A.A, Kent, S.B.H.
登録日2008-08-18
公開日2009-06-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods
Protein Sci., 18, 2009
3E8Y
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BU of 3e8y by Molmil
Xray structure of scorpion toxin BmBKTx1
分子名称: CHLORIDE ION, Potassium channel toxin alpha-KTx 19.1, SULFATE ION
著者Mandal, K, Pentelute, B.L, Tereshko, V, Kossiakoff, A.A, Kent, S.B.H.
登録日2008-08-20
公開日2009-02-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.
J.Am.Chem.Soc., 131, 2009
3E7R
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BU of 3e7r by Molmil
X-ray Crystal Structure of Racemic Plectasin
分子名称: Plectasin
著者Mandal, K, Pentelute, B.L, Tereshko, V, Kossiakoff, A.A, Kent, S.B.H.
登録日2008-08-18
公開日2009-06-09
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods
Protein Sci., 18, 2009
2FD7
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BU of 2fd7 by Molmil
X-ray Crystal Structure of Chemically Synthesized Crambin
分子名称: Crambin
著者Bang, D, Tereshko, V, Kossiakoff, A.A, Kent, S.B.
登録日2005-12-13
公開日2007-01-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Role of a salt bridge in the model protein crambin explored by chemical protein synthesis: X-ray structure of a unique protein analogue, [V15A]crambin-alpha-carboxamide.
Mol Biosyst, 5, 2009
2FCQ
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BU of 2fcq by Molmil
X-ray Crystal Structure of a Chemically Synthesized Ubiquitin with a Cubic Space Group
分子名称: CADMIUM ION, Ubiquitin
著者Bang, D, Gribenko, A.V, Tereshko, V, Kossiakoff, A.A, Kent, S.B, Makhatadze, G.I.
登録日2005-12-12
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis.
Nat.Chem.Biol., 2, 2006
2FD9
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BU of 2fd9 by Molmil
X-ray Crystal Structure of Chemically Synthesized Crambin-{alpha}carboxamide
分子名称: Crambin
著者Bang, D, Tereshko, V, Kossiakoff, A.A, Kent, S.B.
登録日2005-12-13
公開日2007-01-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Role of a salt bridge in the model protein crambin explored by chemical protein synthesis: X-ray structure of a unique protein analogue, [V15A]crambin-alpha-carboxamide.
Mol Biosyst, 5, 2009
2FCM
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BU of 2fcm by Molmil
X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin with a Cubic Space Group
分子名称: ACETATE ION, CADMIUM ION, Ubiquitin
著者Bang, D, Gribenko, A.V, Tereshko, V, Kossiakoff, A.A, Kent, S.B, Makhatadze, G.I.
登録日2005-12-12
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis.
Nat.Chem.Biol., 2, 2006
2FCS
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BU of 2fcs by Molmil
X-ray Crystal Structure of a Chemically Synthesized [L-Gln35]Ubiquitin with a Cubic Space Group
分子名称: ACETATE ION, CADMIUM ION, SULFATE ION, ...
著者Bang, D, Gribenko, A.V, Tereshko, V, Kossiakoff, A.A, Kent, S.B, Makhatadze, G.I.
登録日2005-12-12
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis.
Nat.Chem.Biol., 2, 2006
2FCN
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BU of 2fcn by Molmil
X-ray Crystal Structure of a Chemically Synthesized [D-Val35]Ubiquitin with a Cubic Space Group
分子名称: ACETATE ION, CADMIUM ION, Ubiquitin
著者Bang, D, Gribenko, A.V, Tereshko, V, Kossiakoff, A.A, Kent, S.B, Makhatadze, G.I.
登録日2005-12-12
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis.
Nat.Chem.Biol., 2, 2006
3IVK
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BU of 3ivk by Molmil
Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment
分子名称: CADMIUM ION, CHLORIDE ION, Fab heavy chain, ...
著者Koldobskaya, Y, Duguid, E.M, Shechner, D.M, Koide, S, Kossiakoff, A.A, Bartel, D.P, Piccirilli, J.A.
登録日2009-09-01
公開日2010-03-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of the catalytic core of an RNA-polymerase ribozyme.
Science, 326, 2009
1TPK
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BU of 1tpk by Molmil
CRYSTAL STRUCTURE OF THE KRINGLE-2 DOMAIN OF TISSUE PLASMINOGEN ACTIVATOR AT 2.4-ANGSTROMS RESOLUTION
分子名称: CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR
著者De vos, A.M, Ultsch, M.H, Kelley, R.F, Padmanabhan, K, Tulinsky, A, Westbrook, M.L, Kossiakoff, A.A.
登録日1991-09-24
公開日1992-07-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution.
Biochemistry, 31, 1992
1CA0
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BU of 1ca0 by Molmil
BOVINE CHYMOTRYPSIN COMPLEXED TO APPI
分子名称: BOVINE CHYMOTRYPSIN, PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR
著者Scheidig, A.J, Kossiakoff, A.A.
登録日1997-01-23
公開日1997-07-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Protein Sci., 6, 1997
1CBW
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BU of 1cbw by Molmil
BOVINE CHYMOTRYPSIN COMPLEXED TO BPTI
分子名称: BOVINE CHYMOTRYPSIN, BPTI, SULFATE ION
著者Hynes, T.R, Scheidig, A.J, Kossiakoff, A.A.
登録日1996-12-22
公開日1997-07-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Protein Sci., 6, 1997
5UCB
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BU of 5ucb by Molmil
Structure of antigen-Fab complex with engineered switch residue region.
分子名称: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
著者Bailey, L.J, Kossiakoff, A.A, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)
登録日2016-12-22
公開日2017-12-27
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.521 Å)
主引用文献Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
1AAL
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BU of 1aal by Molmil
STRUCTURAL EFFECTS INDUCED BY MUTAGENESIS AFFECTED BY CRYSTAL PACKING FACTORS: THE STRUCTURE OF A 30-51 DISULFIDE MUTANT OF BASIC PANCREATIC TRYPSIN INHIBITOR
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION
著者Eigenbrot, C, Randal, M, Kossiakoff, A.A.
登録日1992-04-09
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural effects induced by mutagenesis affected by crystal packing factors: the structure of a 30-51 disulfide mutant of basic pancreatic trypsin inhibitor.
Proteins, 14, 1992
5W2B
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BU of 5w2b by Molmil
Crystal structure of C-terminal domain of Ebola (Reston) nucleoprotein in complex with Fab fragment
分子名称: Fab Heavy Chain, Fab Light Chain, Nucleoprotein
著者Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S.
登録日2017-06-06
公開日2018-06-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Acta Crystallogr D Struct Biol, 74, 2018
8T9Y
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BU of 8t9y by Molmil
Structure of VHH-Fab complex with engineered Elbow FNQIKG and Crystal Kappa regions
分子名称: DI(HYDROXYETHYL)ETHER, Fab heavy chain, Fab light chain, ...
著者Filippova, E.V, Thompson, I, Kossiakoff, A.A.
登録日2023-06-26
公開日2023-11-29
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T58
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BU of 8t58 by Molmil
Structure of VHH-Fab complex with engineered FNQIKG elbow region
分子名称: CHLORIDE ION, Fab heavy chain, Fab light chain, ...
著者Filippova, E.V, Kossiakoff, A.A.
登録日2023-06-12
公開日2023-11-29
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024

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