7MO0

Crystal Structure of Nucleoporin NUP50 Ran-Binding Domain in Complex with Ran-GPPNHP

Summary for 7MO0

Entry DOI	10.2210/pdb7mo0/pdb
Descriptor	GTP-binding nuclear protein Ran, Nuclear pore complex protein Nup50, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (6 entities in total)
Functional Keywords	nuclear pore complex component, nucleocytoplasmic transport, transport protein, complex (small gtpase-nuclear protein)
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	81092.75
Authors	Bley, C.J.,Nie, S.,Mobbs, G.W.,Petrovic, S.,Gres, A.T.,Liu, X.,Mukherjee, S.,Harvey, S.,Huber, F.M.,Lin, D.H.,Brown, B.,Tang, A.W.,Rundlet, E.J.,Correia, A.R.,Chen, S.,Regmi, S.G.,Stevens, T.A.,Jette, C.A.,Dasso, M.,Patke, A.,Palazzo, A.F.,Kossiakoff, A.A.,Hoelz, A. (deposition date: 2021-05-01, release date: 2022-06-15, Last modification date: 2022-06-22)
Primary citation	Bley, C.J.,Nie, S.,Mobbs, G.W.,Petrovic, S.,Gres, A.T.,Liu, X.,Mukherjee, S.,Harvey, S.,Huber, F.M.,Lin, D.H.,Brown, B.,Tang, A.W.,Rundlet, E.J.,Correia, A.R.,Chen, S.,Regmi, S.G.,Stevens, T.A.,Jette, C.A.,Dasso, M.,Patke, A.,Palazzo, A.F.,Kossiakoff, A.A.,Hoelz, A. Architecture of the cytoplasmic face of the nuclear pore. Science, 376:eabm9129-eabm9129, 2022 Cited by PubMed: 35679405 DOI: 10.1126/science.abm9129 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation