7MO0
Crystal Structure of Nucleoporin NUP50 Ran-Binding Domain in Complex with Ran-GPPNHP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | GTP-binding nuclear protein Ran | polymer | 217 | 24730.8 | 2 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (Human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
| 2 | B, D (B, D) | Nuclear pore complex protein Nup50 | polymer | 134 | 15221.1 | 2 | UniProt (Q9UKX7) Pfam (PF00638) | Homo sapiens (Human) | 50 kDa nucleoporin,Nuclear pore-associated protein 60 kDa-like,Nucleoporin Nup50 |
| 3 | E, G (A, C) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) | |||
| 4 | F, H (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I (D) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 216 (UniProt: P62826)
B, D: 337 - 468 (UniProt: Q9UKX7)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 335 | - | expression tag |
| Ser 336 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 79903.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1189.1 | |
| All* | Total formula weight | 81092.7 |
