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4RSS
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Crystal structure of tyrosine-protein kinase SYK with an inhibitor
分子名称: 1-[(3-methyl-1-{2-[(1,2,3-trimethyl-1H-indol-5-yl)amino]pyrimidin-4-yl}-1H-pyrazol-4-yl)methyl]azetidin-3-ol, Tyrosine-protein kinase SYK
著者Lee, B.I, Lee, S.J, Choi, J.-S.
登録日2014-11-11
公開日2015-10-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
7C90
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Crystal structure of Cytochrome CL from the marine methylotrophic bacterium Methylophaga aminisulfidivorans MPT (Ma-CytcL)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, Cytochrome c, ...
著者Ghosh, S, Dhanasingh, I, Lee, S.H.
登録日2020-06-04
公開日2020-07-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal Structure of CytochromecLfrom the Aquatic Methylotrophic BacteriumMethylophaga aminisulfidivoransMPT.
J Microbiol Biotechnol., 30, 2020
4HAC
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Crystal Structure of the Mevalonate Kinase from an Archaeon Methanosarcina mazei
分子名称: MAGNESIUM ION, Mevalonate kinase
著者Zhuang, N, Lee, K.H.
登録日2012-09-26
公開日2012-12-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystallization and preliminary X-ray diffraction analysis of mevalonate kinase from Methanosarcina mazei.
Acta Crystallogr.,Sect.F, 68, 2012
5YCN
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Human PPARgamma ligand binding domain complexed with Lobeglitazone
分子名称: (5S)-5-[[4-[2-[[6-(4-methoxyphenoxy)pyrimidin-4-yl]-methyl-amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
著者Jang, J.Y, Han, B.W.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Basis for the Enhanced Anti-Diabetic Efficacy of Lobeglitazone on PPAR gamma.
Sci Rep, 8, 2018
5YCP
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Human PPARgamma ligand binding domain complexed with Rosiglitazone
分子名称: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Nuclear receptor coactivator 1, ...
著者Jang, J.Y, Han, B.W.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Enhanced Anti-Diabetic Efficacy of Lobeglitazone on PPAR gamma.
Sci Rep, 8, 2018
3RUJ
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Crystal Structure of N-terminal region of yeast Atg7
分子名称: Ubiquitin-like modifier-activating enzyme ATG7
著者Hong, S.B, Kim, B.W, Song, H.K.
登録日2011-05-05
公開日2011-11-23
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8.
Nat.Struct.Mol.Biol., 18, 2011
3RUI
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Crystal structure of Atg7C-Atg8 complex
分子名称: Autophagy-related protein 8, Ubiquitin-like modifier-activating enzyme ATG7, ZINC ION
著者Hong, S.B, Kim, B.W, Song, H.K.
登録日2011-05-05
公開日2011-11-23
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.906 Å)
主引用文献Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8.
Nat.Struct.Mol.Biol., 18, 2011
1CZV
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V: DIMERIC CRYSTAL FORM
分子名称: PROTEIN (COAGULATION FACTOR V)
著者Macedo-Ribeiro, S, Bode, W, Huber, R, Kane, W.H, Fuentes-Prior, P.
登録日1999-09-07
公開日1999-11-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of the membrane-binding C2 domain of human coagulation factor V.
Nature, 402, 1999
1CZT
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V
分子名称: PROTEIN (COAGULATION FACTOR V)
著者Macedo-Ribeiro, S, Bode, W, Huber, R, Kane, W.H, Fuentes-Prior, P.
登録日1999-09-07
公開日1999-11-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structures of the membrane-binding C2 domain of human coagulation factor V.
Nature, 402, 1999
1CZS
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V: COMPLEX WITH PHENYLMERCURY
分子名称: PHENYLMERCURY, PROTEIN (COAGULATION FACTOR V)
著者Macedo-Ribeiro, S, Bode, W, Huber, R, Kane, W.H, Fuentes-Prior, P.
登録日1999-09-07
公開日1999-11-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of the membrane-binding C2 domain of human coagulation factor V.
Nature, 402, 1999
2AEB
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Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in immune response.
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase 1, MANGANESE (II) ION
著者Di Costanzo, L, Sabio, G, Mora, A, Rodriguez, P.C, Ochoa, A.C, Centeno, F, Christianson, D.W.
登録日2005-07-21
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1WVA
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Crystal structure of human arginase I from twinned crystal
分子名称: Arginase 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE
著者Di Costanzo, L, Sabio, G, Mora, A, Rodriguez, P.C, Ochoa, A.C, Centeno, F, Christianson, D.W.
登録日2004-12-14
公開日2005-09-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response
Proc.Natl.Acad.Sci.Usa, 102, 2005
5XM3
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Crystal Structure of Methanol dehydrogenase from Methylophaga aminisulfidivorans
分子名称: Glucose dehydrogenase, MAGNESIUM ION, Methanol dehydrogenase [cytochrome c] subunit 2, ...
著者Cao, T.P, Choi, J.M, Lee, S.H.
登録日2017-05-12
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献The crystal structure of methanol dehydrogenase, a quinoprotein from the marine methylotrophic bacterium Methylophaga aminisulfidivorans MPT
J. Microbiol., 56, 2018
7UFV
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Crystal structure of the WDR domain of human DCAF1 in complex with OICR-6766
分子名称: (3P)-N-[(1S)-3-amino-1-(3-chlorophenyl)-3-oxopropyl]-3-(2-fluorophenyl)-1H-pyrazole-4-carboxamide, DDB1- and CUL4-associated factor 1, UNKNOWN ATOM OR ION
著者Kimani, S, Li, A, Li, Y, Dong, A, Hutchinson, A, Seitova, A, Wilson, B, Al-Awar, R, Vedadi, M, Brown, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
登録日2022-03-23
公開日2022-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of Nanomolar DCAF1 Small Molecule Ligands.
J.Med.Chem., 66, 2023
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