6TH6
 
 | | Cryo-EM Structure of T. kodakarensis 70S ribosome | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Matzov, D, Sas-Chen, A, Thomas, J.M, Santangelo, T, Meier, J.L, Schwartz, S, Shalev-Benami, M. | | 登録日 | 2019-11-18 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | | 主引用文献 | Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Nature, 583, 2020
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4IFH
 | | Crystal structure of human insulin degrading enzyme (IDE) in complex with compound BDM44619 | | 分子名称: | Insulin-degrading enzyme, N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)-4-methylbenzamide, ZINC ION | | 著者 | Liang, W.G, Guo, Q, Deprez, R, Deprez, B, Tang, W. | | 登録日 | 2012-12-14 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.286 Å) | | 主引用文献 | Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.
Nat Commun, 6, 2015
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6GS8
 | | Crystal structure of SmbA in complex with c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Uncharacterized protein | | 著者 | Dubey, B.N, Schirmer, T. | | 登録日 | 2018-06-13 | | 公開日 | 2019-07-31 | | 最終更新日 | 2022-07-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Reciprocal growth control by competitive binding of nucleotide second messengers to a metabolic switch in Caulobacter crescentus
Nat Microbiol, 2021
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6GTM
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2IAT
 | | Crystal structure of squid ganglion DFPase W244L mutant | | 分子名称: | CALCIUM ION, Diisopropylfluorophosphatase | | 著者 | Scharff, E.I, Koepke, J, Fritzsch, G, Luecke, C, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris
Structure, 9, 2001
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2IAO
 | | Crystal structure of squid ganglion DFPase E37Q mutant | | 分子名称: | CALCIUM ION, DIISOPROPYLFLUOROPHOSPHATASE | | 著者 | Scharff, E.I, Koepke, J, Fritzsch, G, Luecke, C, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris
Structure, 9, 2001
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2IAV
 | | Crystal structure of squid ganglion DFPase H287A mutant | | 分子名称: | CALCIUM ION, Diisopropylfluorophosphatase | | 著者 | Katsemi, V, Luecke, C, Koepke, J, Loehr, F, Maurer, S, Fritzsch, G, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme
Biochemistry, 44, 2005
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2IAS
 | | Crystal structure of squid ganglion DFPase W244F mutant | | 分子名称: | CALCIUM ION, Diisopropylfluorophosphatase | | 著者 | Scharff, E.I, Koepke, J, Fritzsch, G, Luecke, C, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris
Structure, 9, 2001
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2IAX
 | | Crystal structure of squid ganglion DFPase D232S mutant | | 分子名称: | CALCIUM ION, Diisopropylfluorophosphatase | | 著者 | Katsemi, V, Luecke, C, Koepke, J, Loehr, F, Maurer, S, Fritzsch, G, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme
Biochemistry, 44, 2005
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2IAR
 | | Crystal structure of squid ganglion DFPase W244H mutant | | 分子名称: | CALCIUM ION, Diisopropylfluorophosphatase | | 著者 | Scharff, E.I, Koepke, J, Fritzsch, G, Luecke, C, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris
Structure, 9, 2001
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2IAQ
 | | Crystal structure of squid ganglion DFPase S271A mutant | | 分子名称: | CALCIUM ION, Diisopropylfluorophosphatase | | 著者 | Scharff, E.I, Koepke, J, Fritzsch, G, Luecke, C, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris
Structure, 9, 2001
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2IAW
 | | Crystal structure of squid ganglion DFPase N175D mutant | | 分子名称: | CALCIUM ION, Diisopropylfluorophosphatase | | 著者 | Katsemi, V, Luecke, C, Koepke, J, Loehr, F, Maurer, S, Fritzsch, G, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme
Biochemistry, 44, 2005
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2IAP
 | | Crystal structure of squid ganglion DFPase E21Q mutant | | 分子名称: | CALCIUM ION, Diisopropylfluorophosphatase | | 著者 | Scharff, E.I, Koepke, J, Fritzsch, G, Luecke, C, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris
Structure, 9, 2001
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2IAU
 | | Crystal structure of squid ganglion DFPase W244Y mutant | | 分子名称: | CALCIUM ION, Diisopropylfluorophosphatase | | 著者 | Scharff, E.I, Koepke, J, Fritzsch, G, Luecke, C, Rueterjans, H. | | 登録日 | 2006-09-08 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris
Structure, 9, 2001
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1PJX
 | | 0.85 ANGSTROM STRUCTURE OF SQUID GANGLION DFPASE | | 分子名称: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, ... | | 著者 | Koepke, J, Rueterjans, H, Luecke, C, Fritzsch, G. | | 登録日 | 2003-06-04 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Statistical analysis of crystallographic data obtained from squid ganglion DFPase at 0.85 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
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5M05
 | | Chicken smooth muscle myosin motor domain co-crystallized with the specific CK-571 inhibitor, MgADP form | | 分子名称: | 4-{[(2-chloro-3-fluorobenzyl)carbamoyl](methyl)amino}-3,4-dideoxy-5-O-(isoquinolin-3-ylcarbamoyl)-D-erythro-pentitol, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Sirigu, S, Hartman, J, Houdusse, A. | | 登録日 | 2016-10-03 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.675 Å) | | 主引用文献 | Highly selective inhibition of myosin motors provides the basis of potential therapeutic application.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5T45
 | | Chicken smooth muscle myosin motor domain co-crystallized with the specific CK-571 inhibitor, MgADP.BeFx form | | 分子名称: | 4-{[(2-chloro-3-fluorobenzyl)carbamoyl](methyl)amino}-3,4-dideoxy-5-O-(isoquinolin-3-ylcarbamoyl)-D-erythro-pentitol, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Sirigu, S, Planelles-Herrero, V.J, Hartman, J, Houdusse, A. | | 登録日 | 2016-08-29 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Highly selective inhibition of myosin motors provides the basis of potential therapeutic application.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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1E1A
 | | Crystal structure of DFPase from Loligo vulgaris | | 分子名称: | CALCIUM ION, DIISOPROPYLFLUOROPHOSPHATASE | | 著者 | Koepke, J, Scharff, E.I, Fritzsch, G, Luecke, C, Rueterjans, H. | | 登録日 | 2000-04-28 | | 公開日 | 2001-06-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of Diisopropylfluorophosphatase from Loligo Vulgaris
Structure, 9, 2001
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6I5A
 | | Tobacco Mosaic Virus | | 分子名称: | Capsid protein | | 著者 | Song, B, Flegler, V, Makbul, C, Rasmussen, T, Bottcher, B. | | 登録日 | 2018-11-13 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Capabilities of the Falcon III detector for single-particle structure determination.
Ultramicroscopy, 203, 2019
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5E4M
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5E4D
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5E46
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5E4B
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6ECK
 | | Pyruvate Kinase Isoform L-type with phosphorylated Ser113 (pS113) in complex with FBP | | 分子名称: | 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, CITRATE ANION, ... | | 著者 | Padyana, A, Tong, S. | | 登録日 | 2018-08-08 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production.
Cell Rep, 29, 2019
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6ECH
 | | Pyruvate Kinase Isoform L-type with phosphorylated Ser12 (pS12) in complex with FBP | | 分子名称: | 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Padyana, A, Tong, S. | | 登録日 | 2018-08-07 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production.
Cell Rep, 29, 2019
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