3MIY
 
 | | X-ray crystal structure of ITK complexed with sunitinib | | 分子名称: | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, Tyrosine-protein kinase ITK/TSK | | 著者 | Kuglstatter, A, Villasenor, A.G. | | 登録日 | 2010-04-12 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulation.
Chem.Biol.Drug Des., 76, 2010
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2JR7
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2W4D
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7V61
 | | ACE2 -Targeting Monoclonal Antibody as Potent and Broad-Spectrum Coronavirus Blocker | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3E8, ... | | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | | 登録日 | 2021-08-18 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker.
Signal Transduct Target Ther, 6, 2021
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6XSZ
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6XT1
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6XSX
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5WQ6
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5WC8
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5WC6
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7A4P
 | | Structure of small high-light grown Chlorella ohadii photosystem I | | 分子名称: | (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, (3R)-beta,beta-caroten-3-ol, ... | | 著者 | Caspy, I, Nelson, N, Nechushtai, R, Shkolnisky, Y, Neumann, E. | | 登録日 | 2020-08-20 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM photosystem I structure reveals adaptation mechanisms to extreme high light in Chlorella ohadii.
Nat.Plants, 7, 2021
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6ZZY
 | | Structure of high-light grown Chlorella ohadii photosystem I | | 分子名称: | (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ... | | 著者 | Caspy, I, Nelson, N, Nechushtai, R, Shkolnisky, Y, Neumann, E. | | 登録日 | 2020-08-05 | | 公開日 | 2021-07-28 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Cryo-EM photosystem I structure reveals adaptation mechanisms to extreme high light in Chlorella ohadii.
Nat.Plants, 7, 2021
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6ZZX
 | | Structure of low-light grown Chlorella ohadii Photosystem I | | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, (3R)-beta,beta-caroten-3-ol, ... | | 著者 | Caspy, I, Nelson, N, Nechushtai, R, Neumann, E, Shkolnisky, Y. | | 登録日 | 2020-08-05 | | 公開日 | 2021-07-28 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Cryo-EM photosystem I structure reveals adaptation mechanisms to extreme high light in Chlorella ohadii.
Nat.Plants, 7, 2021
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4W7P
 | | Crystal Structure of ROCK 1 bound to YB-15-QD37 | | 分子名称: | N~1~-[2-(1H-indazol-5-yl)pyrido[3,4-d]pyrimidin-4-yl]-2-methylpropane-1,2-diamine, Rho-associated protein kinase 1 | | 著者 | Sprague, E.R. | | 登録日 | 2014-08-22 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension.
Bioorg.Med.Chem.Lett., 24, 2014
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7UW9
 | | Citrus V-ATPase State 1, H in contact with subunit a | | 分子名称: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit AP1 fragment, V-type proton ATPase subunit AP2 fragment, ... | | 著者 | Keon, K.A, Abdelaziz, R.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | | 登録日 | 2022-05-03 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of V-ATPase from citrus fruit.
Structure, 30, 2022
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7UWB
 | | Citrus V-ATPase State 2, Highest-Resolution Class | | 分子名称: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit AP1 fragment, V-type proton ATPase subunit AP2 fragment, ... | | 著者 | Keon, K.A, Abdelaziz, R.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | | 登録日 | 2022-05-03 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of V-ATPase from citrus fruit.
Structure, 30, 2022
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7UWA
 | | Citrus V-ATPase State 1, H in contact with subunits AB | | 分子名称: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit AP1 fragment, V-type proton ATPase subunit AP2 fragment, ... | | 著者 | Abdelaziz, R.A, Keon, K.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | | 登録日 | 2022-05-03 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure of V-ATPase from citrus fruit.
Structure, 30, 2022
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7UWD
 | | Citrus V-ATPase State 2, H in contact with subunits AB | | 分子名称: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit, V-type proton ATPase subunit AP1 fragment, ... | | 著者 | Keon, K.A, Abdelaziz, R.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | | 登録日 | 2022-05-03 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of V-ATPase from citrus fruit.
Structure, 30, 2022
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7UWC
 | | Citrus V-ATPase State 2, H in contact with subunit a | | 分子名称: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit AP1 fragment, V-type proton ATPase subunit AP2 fragment, ... | | 著者 | Keon, K.A, Abdelaziz, R.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | | 登録日 | 2022-05-03 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure of V-ATPase from citrus fruit.
Structure, 30, 2022
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5KD2
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5KDJ
 | | ZmpB metallopeptidase from Clostridium perfringens | | 分子名称: | F5/8 type C domain protein, GLYCEROL, SODIUM ION, ... | | 著者 | Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B. | | 登録日 | 2016-06-08 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Recognition of protein-linked glycans as a determinant of peptidase activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5KDU
 | | ZmpB metallopeptidase in complex with a2,6-Sialyl T-antigen | | 分子名称: | 1,2-ETHANEDIOL, F5/8 type C domain protein, SERINE, ... | | 著者 | Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B. | | 登録日 | 2016-06-08 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Recognition of protein-linked glycans as a determinant of peptidase activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5KDN
 | | ZmpB metallopeptidase from Clostridium perfringens | | 分子名称: | 1,2-ETHANEDIOL, F5/8 type C domain protein, ZINC ION | | 著者 | Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B. | | 登録日 | 2016-06-08 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Recognition of protein-linked glycans as a determinant of peptidase activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5KDX
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5KD8
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