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1L7M
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HIGH RESOLUTION LIGANDED STRUCTURE OF PHOSPHOSERINE PHOSPHATASE (PI COMPLEX)
分子名称: MAGNESIUM ION, PHOSPHATE ION, Phosphoserine Phosphatase
著者Wang, W, Cho, H.S, Kim, R, Jancarik, J, Yokota, H, Nguyen, H.H, Grigoriev, I.V, Wemmer, D.E, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
登録日2002-03-15
公開日2002-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
J.Mol.Biol., 319, 2002
1L7P
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SUBSTRATE BOUND PHOSPHOSERINE PHOSPHATASE COMPLEX STRUCTURE
分子名称: PHOSPHATE ION, PHOSPHOSERINE, PHOSPHOSERINE PHOSPHATASE
著者Wang, W, Cho, H.S, Kim, R, Jancarik, J, Yokota, H, Nguyen, H.H, Grigoriev, I.V, Wemmer, D.E, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
登録日2002-03-16
公開日2002-06-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
J.Mol.Biol., 319, 2002
1L7O
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CRYSTAL STRUCTURE OF PHOSPHOSERINE PHOSPHATASE IN APO FORM
分子名称: ACETIC ACID, PHOSPHOSERINE PHOSPHATASE, ZINC ION
著者Wang, W, Cho, H.S, Kim, R, Jancarik, J, Yokota, H, Nguyen, H.H, Grigoriev, I.V, Wemmer, D.E, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
登録日2002-03-16
公開日2002-06-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
J.Mol.Biol., 319, 2002
4D3C
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Crystal structure of the NK1 domain of HGF in complex with anti-HGF monoclonal antibody SFN68.
分子名称: HEPATOCYTE GROWTH FACTOR, SFN68 FAB
著者Kang, Y.J, Kim, K.L, Cho, H.S, Chung, J.H.
登録日2014-10-21
公開日2016-01-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist.
to be published
5A2P
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THE COMPLEX STRUCTURE OF PDZ DOMAINS IN SYNTENIN-1 WITH 4L PEPTIDE
分子名称: SYNDECAN-4, SYNTENIN-1
著者Yoo, J.H, Yun, J.H, Cho, H.S, Lee, W.
登録日2015-05-21
公開日2016-06-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.496 Å)
主引用文献Titl the Complex Structure of Pdz Domains in Syntenin-1 with 4L Peptide
To be Published
2JGU
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BU of 2jgu by Molmil
crystal structure of DNA-directed DNA polymerase
分子名称: DNA POLYMERASE, MANGANESE (II) ION
著者Kim, D.U, Cho, H.S.
登録日2007-02-15
公開日2008-04-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Pfu, the High Fidelity DNA Polymerase from Pyrococcus Furiosus.
Int.J.Biol.Macromol., 42, 2008
2IY8
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Crystal structure of the sialyltransferase PM0188 with CMP-3FNeuAc and lactose
分子名称: CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID, PROTEIN PM0188, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Kim, D.U, Cho, H.S.
登録日2006-07-13
公開日2007-09-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of sialyltransferase PM0188 from Pasteurella multocida complexed with donor analogue and acceptor sugar.
Bmb Rep, 41, 2008
2IY7
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crystal structure of the sialyltransferase PM0188 with CMP-3FNeuAc
分子名称: CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID, LPHA-2,3/2,6-SIALYLTRANSFERASE/SIALIDASE
著者Kim, D.U, Cho, H.S.
登録日2006-07-13
公開日2007-08-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural analysis of sialyltransferase PM0188 from Pasteurella multocida complexed with donor analogue and acceptor sugar.
Bmb Rep, 41, 2008
1PUX
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NMR Solution Structure of BeF3-Activated Spo0F, 20 conformers
分子名称: Sporulation initiation phosphotransferase F
著者Gardino, A.K, Volkman, B.F, Cho, H.S, Lee, S.Y, Wemmer, D.E, Kern, D.
登録日2003-06-25
公開日2003-08-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system.
J.Mol.Biol., 331, 2003
2XHS
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Crystal structure of the ligand binding domain of Fushi tarazu factor 1 of Drosophila melanogaster.
分子名称: NUCLEAR HORMONE RECEPTOR FTZ-F1, SEGMENTATION PROTEIN FUSHI TARAZU
著者Yoo, J.H, Cho, H.S.
登録日2010-06-21
公開日2011-07-20
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Fushi Tarazu Factor 1 Ligand Binding Domain/Fushi Tarazu Peptide Complex Identifies New Class of Nuclear Receptors.
J.Biol.Chem., 286, 2011
2X29
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Crystal structure of human4-1BB ligand ectodomain
分子名称: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9
著者Won, E.Y, Cho, H.S.
登録日2010-01-12
公開日2010-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Structure of the Trimer of Human 4-1Bb Ligand is Unique Among Members of the Tumor Necrosis Factor Superfamily.
J.Biol.Chem., 285, 2010
8CHO
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CRYSTAL STRUCTURE OF DELTA5-3-KETOSTEROID ISOMERASE FROM PSEUDOMONAS TESTOSTERONI
分子名称: O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, STEROID DELTA-ISOMERASE
著者Cho, H.-S, Oh, B.-H.
登録日1998-01-06
公開日1999-02-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and enzyme mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni.
Biochemistry, 37, 1998
1M6B
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Structure of the HER3 (ERBB3) Extracellular Domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor protein-tyrosine kinase erbB-3, ...
著者Leahy, D.J, Cho, H.-S.
登録日2002-07-15
公開日2002-08-02
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the extracellular region of HER3 reveals an interdomain tether.
Science, 297, 2002
4YNE
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(R)-2-Phenylpyrrolidine Substitute Imidazopyridazines: a New Class of Potent and Selective Pan-TRK Inhibitors
分子名称: 6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]-3-(pyridin-2-yl)imidazo[1,2-b]pyridazine, GLYCEROL, High affinity nerve growth factor receptor, ...
著者Kreusch, A, Rucker, P, Molteni, V, Loren, J.
登録日2015-03-09
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.0229 Å)
主引用文献(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Acs Med.Chem.Lett., 6, 2015
4YMJ
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(R)-2-Phenylpyrrolidine Substitute Imidazopyridazines: a New Class of Potent and Selective Pan-TRK Inhibitors
分子名称: 4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrile, CHLORIDE ION, GLYCEROL, ...
著者Kreusch, A, Rucker, P, Molteni, V, Loren, J.
登録日2015-03-06
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Acs Med.Chem.Lett., 6, 2015
4YPS
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(R)-2-Phenylpyrrolidine Substitute Imidazopyridazines: a New Class of Potent and Selective Pan-TRK Inhibitors
分子名称: 4-{6-[(3R)-3-(3-fluorophenyl)morpholin-4-yl]imidazo[1,2-b]pyridazin-3-yl}benzonitrile, High affinity nerve growth factor receptor, SULFATE ION
著者Kreusch, A, Rucker, P, Molteni, V, Loren, J.
登録日2015-03-13
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1012 Å)
主引用文献(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Acs Med.Chem.Lett., 6, 2015
8UK7
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Periplasmic domain of Escherichia coli CpxA
分子名称: Sensor histidine kinase CpxA
著者Glover, M.J.N, Murray, C.R.A, Edwards, R.A, Thede, G.L.
登録日2023-10-12
公開日2023-10-25
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim domains.
J.Biol.Chem., 300, 2024
4UIP
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BU of 4uip by Molmil
The complex structure of extracellular domain of EGFR with Repebody (rAC1).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIDERMAL GROWTH FACTOR RECEPTOR, ...
著者Kang, Y.J, Cha, Y.J, Cho, H.S, Lee, J.J, Kim, H.S.
登録日2015-03-31
公開日2015-11-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein-Drug Conjugates for Targeted Therapy.
Angew.Chem.Int.Ed.Engl., 54, 2015
4TSV
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BU of 4tsv by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
分子名称: TUMOR NECROSIS FACTOR-ALPHA
著者Cha, S.-S, Kim, J.-S, Cho, H.-S, Oh, B.-H.
登録日1997-10-29
公開日1998-12-30
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity.
J.Biol.Chem., 273, 1998
1W01
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Crystal structure of mutant enzyme Y57F/D103L of ketosteroid isomerase from Pseudomonas putida biotype B
分子名称: STEROID DELTA-ISOMERASE
著者Jang, D.S, Choi, K.Y.
登録日2004-05-30
公開日2004-07-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Double-Mutant Cycle Analysis of a Hydrogen Bond Network in Ketosteroid Isomerase from Pseudomonas Putida Biotype B.
Biochem.J., 382, 2004
1W02
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Crystal structure of mutant enzyme Y16F/D103L of ketosteroid isomerase from Pseudomonas putida biotype B
分子名称: STEROID DELTA-ISOMERASE
著者Jang, D.S, Choi, K.Y.
登録日2004-05-30
公開日2004-07-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Double-Mutant Cycle Analysis of a Hydrogen Bond Network in Ketosteroid Isomerase from Pseudomonas Putida Biotype B.
Biochem.J., 382, 2004
1W00
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Crystal structure of mutant enzyme D103L of Ketosteroid Isomerase from Pseudomonas putida biotype B
分子名称: STEROID DELTA-ISOMERASE
著者Kim, D.H, Jang, D.S, Nam, G.H, Oh, B.H, Choi, K.Y.
登録日2004-05-30
公開日2005-05-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Double-Mutant Cycle Analysis of a Hydrogen Bond Network in Ketosteroid Isomerase from Pseudomonas Putida Biotype B
Biochem.J., 382, 2004
5YSO
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Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domain with DN200434
分子名称: 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma
著者Cho, S.J, Chin, J.W, Yoon, H.S, Jeon, Y.H, Bae, J.H, Song, J.Y.
登録日2017-11-14
公開日2018-12-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERR gamma ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
Clin.Cancer Res., 25, 2019
5G1D
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The complex structure of syntenin-1 PDZ domain with c-terminal extension
分子名称: SYNDECAN-4, SYNTENIN-1
著者Lee, I, Kim, H, Yun, J.H, Lee, W.
登録日2016-03-25
公開日2016-11-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling.
Sci.Rep., 6, 2016
5G1E
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The complex structure of syntenin-1 PDZ domain with c-terminal extension
分子名称: SYNTENIN-1
著者Lee, I, Kim, H, Yun, J.H, Lee, W.
登録日2016-03-25
公開日2016-11-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling.
Sci.Rep., 6, 2016

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