7N3O
 
 | | Cryo-EM structure of the Cas12k-sgRNA complex | | 分子名称: | Cas12k, Single guide RNA | | 著者 | Chang, L, Li, Z, Xiao, R, Wang, S, Han, R. | | 登録日 | 2021-06-01 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis of target DNA recognition by CRISPR-Cas12k for RNA-guided DNA transposition.
Mol.Cell, 81, 2021
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7N3P
 | | Cryo-EM structure of the Cas12k-sgRNA-dsDNA complex | | 分子名称: | Cas12k, DNA (5'-D(*CP*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*AP*AP*CP*CP*GP*AP*GP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*CP*TP*CP*GP*GP*TP*T)-3'), ... | | 著者 | Chang, L, Li, Z, Xiao, R, Wang, S, Han, R. | | 登録日 | 2021-06-01 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Structural basis of target DNA recognition by CRISPR-Cas12k for RNA-guided DNA transposition.
Mol.Cell, 81, 2021
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8FCJ
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8FCX
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8FCU
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8FD3
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8FCV
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8FCW
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8FF5
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8FF4
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5VVF
 | | Crystal Structure of 354BG1 Fab | | 分子名称: | 1,2-ETHANEDIOL, 354BG1 Heavy Chain, 354BG1 Light Chain | | 著者 | Scharf, L, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2017-05-19 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.
Elife, 6, 2017
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7DK1
 | | Crystal structure of Zinc bound SARS-CoV-2 main protease | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3C-like proteinase, CHLORIDE ION, ... | | 著者 | Sonkar, K.S, Panchariya, L, Kuila, S, Khan, W.A, Arockiasamy, A. | | 登録日 | 2020-11-22 | | 公開日 | 2021-06-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | | 主引用文献 | Zinc 2+ ion inhibits SARS-CoV-2 main protease and viral replication in vitro.
Chem.Commun.(Camb.), 57, 2021
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6NMC
 | | CryoEM structure of the LbCas12a-crRNA-2xAcrVA1 complex | | 分子名称: | AcrVA1, Cpf1, MAGNESIUM ION, ... | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | | 主引用文献 | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
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5F7E
 | | Crystal structure of germ-line precursor of 3BNC60 Fab | | 分子名称: | Fab heavy chain, Fab light chain | | 著者 | Sievers, S.A, Scharf, L, Jiang, S, Bjorkman, P.J. | | 登録日 | 2015-12-08 | | 公開日 | 2016-04-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
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6FX0
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1H6P
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7JZZ
 | | Cryo-EM structure of CRISPR-Cas surveillance complex with AcrIF14 | | 分子名称: | AcrF14, CRISPR type I-F/YPEST-associated protein Csy3, CRISPR-associated protein Csy1, ... | | 著者 | Chang, L, Li, Z, Gabel, C. | | 登録日 | 2020-09-02 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for inhibition of the type I-F CRISPR-Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14.
Nucleic Acids Res., 49, 2021
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7JZX
 | | Cryo-EM structure of CRISPR-Cas surveillance complex with AcrIF7 | | 分子名称: | AcrF7, CRISPR type I-F/YPEST-associated protein Csy3, CRISPR-associated endonuclease Cas6/Csy4, ... | | 著者 | Chang, L, Li, Z, Gabel, C. | | 登録日 | 2020-09-02 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for inhibition of the type I-F CRISPR-Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14.
Nucleic Acids Res., 49, 2021
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7JZW
 | | Cryo-EM structure of CRISPR-Cas surveillance complex with AcrIF4 | | 分子名称: | CRISPR repeat sequence, CRISPR type I-F/YPEST-associated protein Csy1, CRISPR type I-F/YPEST-associated protein Csy2, ... | | 著者 | Chang, L, Li, Z, Gabel, C. | | 登録日 | 2020-09-02 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for inhibition of the type I-F CRISPR-Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14.
Nucleic Acids Res., 49, 2021
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4FQ1
 | | Crystal Structure of PGT121 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain | | 著者 | Scharf, L, Bjorkman, P.J. | | 登録日 | 2012-06-24 | | 公開日 | 2012-11-14 | | 最終更新日 | 2021-05-19 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FQ2
 | | Crystal Structure of 10-1074 Fab | | 分子名称: | 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ... | | 著者 | Scharf, L, Bjorkman, P.J. | | 登録日 | 2012-06-24 | | 公開日 | 2012-11-14 | | 最終更新日 | 2021-05-19 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FQC
 | | Crystal Structure of PGT121 Fab Bound to a complex-type sialylated N-glycan | | 分子名称: | Fab heavy chain, Fab light chain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Scharf, L, Bjorkman, P.J. | | 登録日 | 2012-06-25 | | 公開日 | 2012-11-14 | | 最終更新日 | 2021-05-19 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FQQ
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7L49
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7L48
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