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3GNA
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BU of 3gna by Molmil
Crystal structure of the RAG1 nonamer-binding domain with DNA
分子名称: 5'-D(*AP*CP*TP*TP*AP*AP*CP*AP*AP*AP*AP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*TP*TP*TP*TP*GP*TP*TP*AP*AP*G)-3', V(D)J recombination-activating protein 1
著者Yin, F.F, Bailey, S, Innis, C.A, Steitz, T.A, Schatz, D.G.
登録日2009-03-16
公開日2009-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis.
Nat.Struct.Mol.Biol., 16, 2009
5H9F
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BU of 5h9f by Molmil
Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target at 2.45 angstrom resolution.
分子名称: CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
著者Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A.
登録日2015-12-28
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
Nature, 530, 2016
5H9E
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Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target (32-nt spacer) at 3.20 angstrom resolution.
分子名称: CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
著者Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A.
登録日2015-12-28
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
Nature, 530, 2016
1E1D
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BU of 1e1d by Molmil
Hybrid Cluster Protein from Desulfovibrio vulgaris
分子名称: HYDROXYLAMINE REDUCTASE, IRON/SULFUR CLUSTER, IRON/SULFUR/OXYGEN HYBRID CLUSTER
著者Arendsen, A.F, Cooper, S.J, Bailey, S, Garner, C.D, Hagen, W.R, Lindley, P.F.
登録日2000-05-02
公開日2000-06-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Hybrid-Cluster Protein (Hcp) from Desulfovibrio Vulgaris (Hildenborough) at 1.6 A Resolution.
Biochemistry, 39, 2000
1E2U
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BU of 1e2u by Molmil
Low Temperature Structure of Hybrid Cluster Protein from Desulfovibrio vulgaris to 1.6A
分子名称: HYDROXYLAMINE REDUCTASE, IRON/SULFUR CLUSTER, IRON/SULFUR/OXYGEN HYBRID CLUSTER
著者Cooper, S.J, Bailey, S, Hagen, W.R, Lindley, P.F.
登録日2000-05-26
公開日2000-12-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Hybrid-Cluster Protein (Hcp) from Desulfovibrio Vulgaris (Hildenborough) at 1.6 A Resolution.
Biochemistry, 39, 2000
1DMR
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BU of 1dmr by Molmil
OXIDIZED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DMSO REDUCTASE, MOLYBDENUM(VI) ION, ...
著者Mcalpine, A.S, Bailey, S.
登録日1997-04-22
公開日1998-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Molybdenum Active Centre of Dmso Reductase from Rhodobacter Capsulatus: Crystal Structure of the Oxidised Enzyme at 1.82-A Resolution and the Dithionite-Reduced Enzyme at 2.8-A Resolution
J.Biol.Inorg.Chem., 2, 1997
1E9V
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BU of 1e9v by Molmil
XENON BOUND IN HYDROPHOBIC CHANNEL OF HYBRID CLUSTER PROTEIN FROM DESULFOVIBRIO VULGARIS
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETIC ACID, ...
著者Cooper, S.J, Bailey, S, Rizkallah, P.J, Lindley, P.F.
登録日2000-10-27
公開日2001-10-25
最終更新日2020-12-23
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Ferricyanide Soaked Hybrid Cluster Protein at 1.2A and Xenon Mapping of the Hydrophobic Cavity at 1.8A
To be Published
1H76
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BU of 1h76 by Molmil
The crystal structure of diferric porcine serum transferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Hall, D.R, Hadden, J.M, Leonard, G.A, Bailey, S, Neu, M, Winn, M, Lindley, P.F.
登録日2001-07-03
公開日2002-01-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Crystal and Molecular Structures of Diferric Porcine and Rabbit Serum Transferrins at Resolutions of 2.15 And 2.60A, Respectively
Acta Crystallogr.,Sect.D, 58, 2002
1JNF
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BU of 1jnf by Molmil
Rabbit serum transferrin at 2.6 A resolution.
分子名称: CARBONATE ION, CHLORIDE ION, FE (III) ION, ...
著者Hall, D.R, Hadden, J.M, Leonard, G.A, Bailey, S, Neu, M, Winn, M, Lindley, P.F.
登録日2001-07-24
公開日2001-08-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The crystal and molecular structures of diferric porcine and rabbit serum transferrins at resolutions of 2.15 and 2.60 A, respectively.
Acta Crystallogr.,Sect.D, 58, 2002
3CB4
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BU of 3cb4 by Molmil
The Crystal Structure of LepA
分子名称: GTP-binding protein lepA
著者Evans, R.N, Blaha, G, Bailey, S, Steitz, T.A.
登録日2008-02-21
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structure of LepA, the ribosomal back translocase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3E0D
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BU of 3e0d by Molmil
Insights into the Replisome from the Crystral Structure of the Ternary Complex of the Eubacterial DNA Polymerase III alpha-subunit
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase III subunit alpha, ...
著者Wing, R.A, Bailey, S, Steitz, T.A.
登録日2008-07-31
公開日2008-09-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III alpha-Subunit.
J.Mol.Biol., 382, 2008
3E3J
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BU of 3e3j by Molmil
Crystal Structure of an Intermediate Complex of T7 RNAP and 8nt of RNA
分子名称: DNA (28-MER), DNA (5'-D(*DTP*DAP*DAP*DTP*DAP*DCP*DGP*DAP*DCP*DTP*DCP*DAP*DCP*DTP*DAP*DTP*DAP*DTP*DTP*DTP*DCP*DTP*DGP*DCP*DCP*DAP*DAP*DAP*DCP*DGP*DGP*DC)-3'), DNA-directed RNA polymerase, ...
著者Durniak, K.J, Bailey, S, Steitz, T.A.
登録日2008-08-07
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (6.7 Å)
主引用文献The structure of a transcribing t7 RNA polymerase in transition from initiation to elongation
Science, 322, 2008
2FZZ
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BU of 2fzz by Molmil
Factor Xa in complex with the inhibitor 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(2'-(((3r)-3-hydroxy-1-pyrrolidinyl)methyl)-4-biphenylyl)-3-(trifluoromethyl)-1,4,5,6-tetrahydro-7h-pyrazolo[3,4-c]pyridin-7-one
分子名称: 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-6-(2'-{[(3R)-3-HYDROXYPYRROLIDIN-1-YL]METHYL}BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-1,4,5,6-TETRAHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE, Coagulation factor X
著者Alexander, R.S.
登録日2006-02-10
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.
Bioorg.Med.Chem.Lett., 16, 2006
8JSM
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BU of 8jsm by Molmil
The structure of EBOV L-VP35-RNA complex (conformation 1)
分子名称: Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome., ...
著者Qi, P, Yi, S.
登録日2023-06-20
公開日2023-09-27
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular mechanism of de novo replication by the Ebola virus polymerase.
Nature, 622, 2023
8JSL
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BU of 8jsl by Molmil
The structure of EBOV L-VP35-RNA complex
分子名称: Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV, ...
著者Qi, P, Yi, S.
登録日2023-06-20
公開日2023-09-27
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Molecular mechanism of de novo replication by the Ebola virus polymerase.
Nature, 622, 2023
8JSN
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BU of 8jsn by Molmil
The structure of EBOV L-VP35-RNA complex (conformation 2)
分子名称: Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome, ...
著者Qi, P, Yi, S.
登録日2023-06-20
公開日2023-09-27
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular mechanism of de novo replication by the Ebola virus polymerase.
Nature, 622, 2023
3M35
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Trypsin in complex with the inhibitor 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423)
分子名称: 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide, CALCIUM ION, Cationic trypsin
著者Alexander, R.S.
登録日2010-03-08
公開日2010-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N-[3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor
J.Med.Chem., 46, 2003
3M36
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Factor XA in complex with the inhibitor 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423)
分子名称: 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide, CALCIUM ION, Coagulation factor X
著者Alexander, R.S.
登録日2010-03-08
公開日2010-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N-[3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor
J.Med.Chem., 46, 2003
3M37
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Factor XA in complex with the inhibitor 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC602)
分子名称: 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide, CALCIUM ION, Coagulation factor X
著者Alexander, R.S.
登録日2010-03-08
公開日2010-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N-[3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor.
J.Med.Chem., 46, 2003
1Z6E
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Factor XA in complex with the inhibitor 1-(3'-amino-1,2-benzisoxazol-5'-yl)-n-(4-(2'-((dimethylamino)methyl)-1h-imidazol-1-yl)-2-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (razaxaban; DPC906; BMS-561389)
分子名称: 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-N-(4-{2-[(DIMETHYLAMINO)METHYL]-1H-IMIDAZOL-1-YL}-2-FLUOROPHENYL)-3-(TRIFLUOROMETHYL) -1H-PYRAZOLE-5-CARBOXAMIDE, Coagulation factor X
著者Alexander, R.S.
登録日2005-03-22
公開日2006-03-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4-[(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor.
J.Med.Chem., 48, 2005
7XPP
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BU of 7xpp by Molmil
Crystal Structure of UDP-Glc/GlcNAc 4-Epimerase with NAD
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase
著者Chen, Y.H, Wang, X.C, Zhang, C.R.
登録日2022-05-05
公開日2023-05-24
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis.
Nat Commun, 14, 2023
7XPO
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Crystal Structure of UDP-Glc/GlcNAc 4-Epimerase with NAD/UDP-Glc
分子名称: GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase, ...
著者Chen, Y.H, Wang, X.C, Zhang, C.R.
登録日2022-05-05
公開日2023-05-17
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis.
Nat Commun, 14, 2023
7XPQ
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Crystal Structure of UDP-Glc/GlcNAc 4-Epimerase with NAD/UDP-GlcNAc
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Chen, Y.H, Wang, X.C, Zhang, C.R.
登録日2022-05-05
公開日2023-05-17
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis.
Nat Commun, 14, 2023
7CLV
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Solution structure of mitochondrial Tim23 channel in complex with a signaling peptide
分子名称: COX4 isoform 1, TIM23 isoform 1
著者Zhou, S, Ruan, M.S, Li, Y.Y, Yang, J, Richter, C, Schwalbe, H, Shen, B, Wang, J.F.
登録日2020-07-22
公開日2020-12-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the voltage-gated Tim23 channel in complex with a mitochondrial presequence peptide.
Cell Res., 31, 2021
4RE2
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Different transition state conformations for the hydrolysis of beta-mannosides and beta-glucosides in the rice Os7BGlu26 family GH1 beta-mannosidase/beta-glucosidase
分子名称: (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Tankrathok, A, Iglesias-Fernandez, J, Williams, R.J, Hakki, Z, Robinson, R.C, Hrmova, M, Rovira, C, Williams, S.J, Ketudat Cairns, J.R.
登録日2014-09-21
公開日2015-09-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Single Glycosidase Harnesses Different Pyranoside Ring Transition State Conformations for Hydrolysis of Mannosides and Glucosides
ACS CATALYSIS, 5, 2015

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